纤维软骨

OBJECTIVE: To construct discitis animal model by destroying the fibrous ring and the cartilage lamina through the surgery, in addition, to explore the changes of autoimmune reaction.

目的：通过手术破坏纤维环和软骨终板建立椎间盘炎的动物模型，探讨自免疫状态表达变化过程。

①Discitis animal model can be established by using the anterior external surgery to destroy the fibrous ring and the cartilage lamina.

①运用前外侧入路手术破坏纤维环及软骨终板可以建立椎间盘炎动物模型。

METHODS: Thirty rabbits were randomly selected after anesthetized, L3-4, L4-5, L5-6 intervertebral discs were exposed, discitis models were created by destroying the fibrous ring and the cartilage lamina with self-made transfixion pin.

随机取30只兔麻醉后，暴露L3~4，L4~5，L5~6椎间盘，以自制鹅头穿刺针刺入椎间盘，破坏纤维环和软骨终板建立兔腰椎间盘炎模型。

The pulmonary hamartoma is seen microscopically to be composed mostly of benign cartilage on the right that is jumbled with a fibrovascular stroma and scattered bronchial glands on the left.

图示的是显微镜下肺错构瘤的形态学变化，在图右侧可见大部分良性软骨组织，左侧可见纤维血管基质和支气管腺体混杂在一起。

Results: The degenerative changes were demonstrated in the knee joints injected with papain and L-cysteine, such as the lower activity scope of knee joint, thinner and worse articular cartilage, fissuration, fibrous degeneration, fibrillation and destroyed cartilage matrix.

结果：实验侧关节注射木瓜蛋白酶后，活动范围明显低于对照侧，关节软骨变薄且有裂隙形成、纤维变性、基质分解破坏等退行性改变，并随观察时间的延长而进一步发展。

Results:MRI showed degeneration of meniscus in 16 joints,tearing in 7,changing of articular cartilage in 3,relaxing and thinning of lig.cruciatum anterius in 2 and lig.cruciatum posterius in 3,hydrarthrus in 6,changing synovial bursa and fibrous capsule each in 1.All these changes can not be seen in X-ray films.

结果：MRI显示半月板变性16个，撕裂7个；3个有关节软骨病变；前交叉韧带松弛变细2个，后交叉韧带病变3个；关节腔积液6个；滑囊、纤维囊病变各1个，而X线平片均无上述表现。

Methods All of rats were randomly divided into seven groups and were intratracheally infused with bleomycin to build the model.

大鼠麻醉后，经气管软骨环间隙向心端穿刺，气管内注入博莱霉素A5(5 mg/kg)建立大鼠肺纤维化模型，假手术组大鼠在同样麻醉条件下气管内注入等量生理盐水。

PPO gene was not detected in the multiple myelome、 malignant fibrous histiocytoma 、malignant lymphoma、malignant neurosarcoma、solitary plasmacytoma of bone、primitive neuroectodermal tumors、lipoma、 osteosarcoma and sarcoenchondroma.

PPO基因在多发性骨髓瘤、恶性纤维组织细胞瘤、恶性淋巴瘤、恶性神经肉瘤、孤立性浆细胞肉瘤、原始神经外胚瘤、脂肪瘤、骨及软骨肉瘤等肿瘤中没有表达。在骨巨细胞瘤中有微弱表达。

The stem cells may be induced to express at least one characteristic of human intervertebral disc cells, such as fibroblast cells, chondrocyte cells, or notochordal cells, by exposing them to agents and/or environments calculated to induce the desired differentiation.

可通过干细胞暴露于诱导所需分化的试剂和/或环境来诱导它们表达至少一种人椎间盘细胞，如成纤维细胞、软骨细胞或背索细胞的特征。

Methods: Immunohistochemical study of CD133 expression: 55 cases osteosarcoma conventional paraffin-embedded tissues specimens come from Pathology Department Qilu Hospital Shandong University, including 4 cases parosteal osteosarcoma, 13 cases fibroblast-type osteosarcoma , 12 cases chondroblastic osteosarcoma and 26 cases Osteoblastoma osteosarcoma.

免疫组化研究CD133的表达：取自本院病理科的骨肉瘤常规石蜡包埋组织蜡块标本55例，其中骨旁骨肉瘤4例，纤维母细胞型骨肉瘤13例，软骨母细胞型骨肉瘤12例，骨母细胞型骨肉瘤26例，切成3μm的组织切片备用。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失