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In the pathological proceeding of pulmonary fibrosis, myofibroblast plays an important role, such as: the abnormal extracellular matrix deposition causing by the remarkable capability of collagen synthesis, derogation of the lung compliance owning to the contractibility of myofibroblast,secreting many cytokines,which contribute to the damage of the alveolar epithelial cells.

肌成纤维细胞在PF的病理进程中扮演着重要的角色,其胶原合成能力强可造成细胞外基质的异常沉积、具收缩性使肺顺应性下降、分泌多种炎性介质加重肺泡上皮损伤。

BACKGROUND: Muscle-derived stem cells have some problems in purification, amplification and directional differentiation during in vitro culture. Basic fibroblast growth factor as a membrane of bioactive factor has been paid great attention, due to its biological activity.

背景:肌源性干细胞在体外培养过程中存在纯化、扩增、定向分化等难题,碱性成纤维细胞生长因子作为生物活性因子的一员,因其生物活性的多效性而备受关注。

OBJECTIVE: To explore effects of basic fibroblast growth factor on in vitro proliferation of rat muscle-derived stem cells.

目的:探讨碱性成纤维细胞生长因子对大鼠肌源性干细胞体外增殖的影响。

Lesion was made by current of 1mA, 210s in the dorsal funiculus at the 10th thoracic vertebral level. Behavioral and histological evaluation, HRP and fast blue retrograde labelling method were employed. The eletrolytic current caused bilateral corticospinal tract injury and incomplete paraplegia in hind limbs, and led to a substantial atrophy of corticospinal motoneurons , serving as a reproducible and practical model for research on SCI.

在大鼠T10胸椎节段脊髓后索插入损毁电极,通电1mA,210s,应用行为学评分、脊髓局部组织学检查、HRP和荧光逆行示踪方法发现,电解损伤造成了双侧皮质脊髓束纤维受损,大鼠双侧后肢肌力下降、肌张力升高、运动功能下降,同时大脑运动皮层处皮质脊髓束胞体发生明显逆行性萎缩,可作为一个稳定、可靠的SCI模型。

Results: All rats in experiment group devloped CAG at the end of 12 weeks with the following Pathological changes of CAG such as thin mucosa layer, thick muscle layer, decreased glandes, soakaging inflammation cells in microscope and with the time prolonging, the atrophy of gastric mucosa became more serious; In normal control group and normal feeding group, the IL-6 and IL-8 content in blood serum are the same at every time point; In experiment group, IL-6 became increased from 4wk and kept high level from 4wk to l2wk and had significant difference compared with normal controls.

结果:灌胃至12wk时出现胃粘膜层变薄,固有层腺体减少,固有层纤维结缔组织增生,粘膜肌层明显增生,慢性炎细胞浸润等萎缩性胃炎表现,随著热盐水灌胃时间的延长,32wk胃粘膜萎缩程度明显加重;正常对照组和正常餵养组大鼠各时间点血清IL-6,IL-8含量基本相同。

What the microscope thinning out the skin tumour malignantly sees has it's characteristic is that the identical tumour of outward appearance forms festival in single's tumour tubercles or naked eyes having the obvious various block of wood Same organization is constitutive.

单个纤维性胸膜间皮瘤。从脏层胸膜生长,平板或肉茎状,肿瘤引起临床症状是由于它们扩大发展,挤压胸内结构使其移位,如能早期诊断,可作手术治疗。②广泛扩散的间皮瘤。此类型侵犯肺叶,浸润膈肌、肋间肌,可通过纵隔胸膜而累及心包和大血管。

Methods Nine patients suffered from upper plexus thoracic outlet syndrome was operated in this way: after local block, an incision 1.5 cm in length was made at the lateral neck, the tendon-like origin fiber of anterior and middle scalene muscles was cut partially under the endoscope.

为9例上干型胸廓出口综合征患者局麻下通过颈外侧区作长1.5cm切口,在内窥镜辅助下切断部分前、中斜角肌的腱性起始纤维。

"Mud pack therapy, alone or in combination with other modalities of balneotherapy, has been reported in randomized, double-blinded, controlled studies to improve symptoms of rheumatoid arthritis, psoriatic arthritis, fibromyalgia, and osteoarthritis," write Daniel Flusser and colleagues from Ben Gurion University of the Negev in Beer-Sheva, Israel.

以色列Beer-Sheva的Negev大学的Dr。 Daniel Flusser及其同事提道:以前有随机双盲对照试验报告,泥浆敷布治疗法,不论是单独使用还是与其他形式的浴疗法联合使用,都可以改善风湿性关节炎、牛皮癣的关节炎、纤维性肌痛症以及骨关节炎的症状。

While symptoms may seem to improve almost immediately after surgery, it takes approximately 6-12 months before new vessels develop sufficiently. Diseases associated with moyamoya include sickle cell anemia, atherosclerosis, prior radiation therapy to the skull base in children, and less commonly neurofibromatosis, tuberous sclerosis, meningitis, retinitis pigmentosa, fibromuscular dysplasia, Down's syndrome and Fanconi's anemia.

手术之后几乎立即可以看到症状的好转,新的血供充分发展起来大概要花6-12月时间。moyamoya相关的疾病包括镰状细胞性贫血、动脉粥样硬化、颅底部放疗,不太常见的有神经纤维瘤病,结节性硬化、脑膜炎、色素性视网膜炎、纤维性肌发育不良、Down氏综合症和Fanconi's 贫血症

Detail Contents: Genetic disorders -- Immune deficiencies -- Breast cancer -- Colon cancer -- Melanoma -- Cystic fibrosis -- Hemophilia -- Liver disease -- Cardiovascular disease -- Muscular dystrophy -- Alzheimer's disease -- Parkinson's disease -- Huntington's disease -- Viruses: the cornerstone of gene therapy -- Viruses are living crystals -- Viral genomes may be RNA or DNA -- Viruses evolved from plasmids -- Viruses know how to infect cells -- The virus as a gene vehicle -- Viruses used in gene therapy -- Ashi DeSilva: a promising start -- Clinical trials defined -- Cells of the immune system -- Adenosine deaminase -- Preliminary research -- Clinical procedure for ADA gene therapy -- The DeSilva clinical trial -- Jesse Gelsinger: down to earth -- Ornithine transcarbamylase -- Preliminary research -- Clinical procedure for OTC gene therapy -- The Gelsinger clinical trial -- The investigation -- Concluding remarks -- Future prospects -- Safer vehicles -- Reducing immune rejection of the vector -- Improved risk assessment -- Redesigning human anatomy and physiology -- Ethics of gene therapy -- The Belmont report -- Clinical trials -- Physiological enhancement -- Cosmetic applications -- Legal issues -- Regulatory agencies -- The Gelsinger legal trial -- International regulation -- Resource center -- Eucaryote cell primer -- Recombinant DNA primer -- The human genome project -- X-linked severe combined immunodeficiency (SCID-X1)-- Alzheimer's disease -- Huntington's disease.

细节内容︰遗传疾病-免疫的缺乏-乳腺癌-结肠癌-黑瘤-囊性纤维变性-血友症-肝疾病-心血管疾病-肌营养不良-早老性痴呆病-帕金森疾病-亨廷顿疾病-病毒︰基础的基因治疗-病毒在活著水晶--病毒的基因可能是RNA或者DNA --病毒从plasmids被逐步形成--病毒知道怎样感染细胞--作为一辆基因车辆的病毒--基因治疗使用的病毒-Ashi DeSilva︰有希望开始-临床试验确定--细胞的这免疫系统-Adenosine deaminase-初步研究-临床程式给埃达基因治疗--这DeSilva临床试验-婕西Gelsinger︰到地球-Ornithine transcarbamylase-初步研究-临床程式给OTC基因治疗-- Gelsinger临床试验-调查-达成评论-前景-更安全的车辆--矢量的降低免疫的拒绝-改进风险估计-重新设计人解剖学和生理学--伦理学的基因治疗-那些贝拉蒙特报告-临床试验-生理提升-美容应用-法律问题-协调机构-- Gelsinger 合法审讯-国际管理-资源中心人物-Eucaryote信元第一-Recombinant DNA 入门--人类基因工程-- X 连结的严重的结合的免疫缺陷(SCID-X1)-早老性痴呆病--亨廷顿的疾病。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

The shamrock is the symbol of Ireland and of St.

三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。