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纤维肉瘤

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The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma; therefore, a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy.

对於病理医师和临床医师来说,区分出这个纤维神经瘤的变异型非常重要,因为异生细胞纤维神经瘤在组识学上和细胞学上都非常类似肉瘤,因此正确的诊断出这个纤维神经瘤的变异型是必要的,因为临床上对於良性和恶性肿瘤的治疗和肿瘤行为表现是不同的。

The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma therefore , a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy .

对於病理医师和临床医师来说,区分出这个纤维神经瘤的变异型非常重要,因为异生细胞纤维神经瘤在组织学上和细胞学上都非常类似肉瘤,因此正确的诊断出这个纤维神经瘤的变异型是必要的,因为临床上对於良性和恶性肿瘤的治疗和肿瘤行为表现是不同的。

Methods Twenty - four patients with CP 11 cases were treated by local excision of breast CP,10 cases were treated by mastectomy,3 cases by mastecxomy and axiUary node dissection,and 5 cases of 24 cases underwent local excision(2-3 times) for tumor recurrence post operation,who were diagnosed as adenofibroma or massive adenofibroma of the breast.

方法对24例乳腺叶状囊肉瘤患者采用局部切除11例,单侧乳房切除术10例,乳房切除并腋窝淋巴结清除3例,其中5例(20%)曾诊断为乳腺腺纤维瘤或巨纤维瘤因术后肿瘤复发而经历2~3次局部切除术。

A total of 150 mesenchymal neoplasms of the GI tract, abdominal cavity, and retroperitoneum were retrieved from consult and surgical pathology archives, including 54 GISTs (8 KIT-negative; 13 desmin-positive), 17 GI leiomyosarcomas, 11 GI mural leiomyomas, 13 leiomyomas of the muscularis mucosae, 12 gastric schwannomas, 15 inflammatory myofibroblastic tumors, 9 cases of mesenteric desmoid fibromatosis, 10 dedifferentiated liposarcomas, and 9 malignant peripheral nerve sheath tumors.

我们从会诊病例及活检病例中找出150例间叶性肿瘤(来自胃肠道、腹腔和后腹膜),其中包括54例GISTs(8例KIT阴性、13例desmin阳性)、17例GI道平滑肌肉瘤、11例GI道肌壁间平滑肌瘤、13例GI道粘膜肌层平滑肌瘤、12例胃的神经鞘瘤、15例炎性肌纤维母细胞瘤、9例肠系膜韧带样纤维瘤、10例去分化型脂肪肉瘤和9例恶性外周神经鞘膜瘤。

Results All the 7 cases were female, 2 cases were solitary fibrous tumor, 2 cases were myofibroblastoma, 1 case was inflammatory myofibroblastic tumour, 1 case was fibromatosis, and 1 case was low grade myofibroblastic sarcoma.

结果 7例患者均为女性,2例为孤立性纤维性肿瘤;2例为肌纤维母细胞瘤;1例为纤维瘤病;1例为炎性肌纤维母细胞瘤;1例为低度恶性肌纤维母细胞肉瘤。

First described in 1955, nodular fasciitis, or pseudo sarcomatous fibromatosis, is a benign, self-limiting reactie process composed of proliferating fibroblasts in a myxoid stroma.

序论结节性筋膜炎,或称假肉瘤样纤维瘤病于1955年首次提出,是良性的自限性反应性病变,其粘液间质由增生的成纤维细胞组成。

RESULTS: In 1365 patient undergoing resection of primary RPS, the most prevalent histologies were liposarcoma (50%), leiomyosarcoma (26%), and malignant fibrous histiocytoma (11%).

结果:1365例接受过首次RPS切除术的患者中,最常见的组织学分型为脂肪肉瘤(50%),平滑肌肉瘤(26%),恶性纤维组织细胞瘤(11%)。

The postoperative pathology confirmed that cortical carcinoma was found in 5 cases and pheochromocytoma in 20 cases, malignant pheochromocytoma in 4 cases, malignant fibrous histiocytoma in 1 case, neurocytoma in 1 case, myelolipoma in 1 case, dysembryoma in 1 case, dysembryo-sarcoma in 1 case, well-differentiated liposarcoma in 1 case respectively.

术后病理提示皮质癌5例;嗜铬细胞瘤20例;恶性pheo 4例;恶性纤维组织细胞瘤1例;节神经细胞瘤1例;髓样脂肪瘤1例;畸胎瘤1例;畸胎肉瘤1例;高分化脂肪肉瘤1例。

When Fas and c-myc protein were coexpressed in cytoplasm, a strong positive sign appeared in highly differentiated osteosarcoma, fibrous dysplasia of bone and osteoplast of bone callus, a weak sign was found in low-differentiated tumour cells and fibroblasts.

Fas和c-myc蛋白胞浆内阳性,在骨肉瘤的高分化细胞(骨母细胞型和软骨细胞型瘤细胞)和骨化性纤维瘤、骨纤维结构不良、骨痂组织中骨母细胞呈强表达;而在低分化瘤细胞和纤维母细胞则呈弱表达。

FDCS is a rare malignant tumor and differential diagnosis includes Langerhans cell sarcoma,interdigitating dentric cell sarcoma, malignant fibrous histocytoma, melanoma, metastatic spindle cell carcinoma and others.

正确诊断需要病理组织形态、电镜及免疫组织化学相结合,并应与朗格汉斯细胞肉瘤、指突状树突状细胞肉瘤、恶性纤维组织细胞瘤、黑色素瘤、梭形细胞癌等相鉴别。

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