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MAIN OUTCOME MEASURE: The changes of the morphologic hippocampal pyramidal cell and GFAP expression of astrocyte.

主要观察指标:观察海马锥体细胞形态学变化及星形胶质细胞胶质纤维酸性蛋白表达的变化。

The series of changes in quantiative and spatial distribution of the three cytoskeleton elements throughout the maturation course of FVA cells was coincided with the process of nucleus eccentricity in position and denucleation, and all of the changes began at the early stage of erythroblast.

一。采用细胞免疫荧光组化方法系统地观察了微丝、微管和中间纤维骨架成分在红系细胞终末分化各阶段的动态变化。

In the first week of renal obstruction, the immunohistochemical labeling of tubular VEGF was intensified, accompanied by deformation and dilation of adjacent Flk-1-positive PTC lumina, mild renal tubular cell apoptosis and minimal tubulointerstitial fibrosis.

结果: 1。肾脏梗阻第一周,肾小管上皮细胞胞浆里的VEGF染色在局部有增强,Flk-1阳性PTC数量变化不显著,肾小管上皮细胞凋亡和肾间质纤维化很少见。

It is, therefore, proposed that EMT may occur in CsA-induced fibrosis in gingiva.

因此,上皮细胞-间叶细胞转变被推断可能有发生在藉由环孢灵刺激而产生的牙龈纤维化中。

It is a new discovery to prove the expression of hepatocyte elastase mRNA from morphology. It can be infered that it is related to metabolism of hepatic ground substance. It may be of value to study the development and degradation of hepatic fiber.

从形态学证实肝脏细胞有弹力蛋白酶mRNA的表达,丝氨酸弹力蛋白酶有可能参与肝纤维化细胞外基质代谢

Objective To study the role of mast cells and mast cell protease 1(RMCP 1)in the myocardial fibrosis after myocardial infarction in rats.

目的观察肥大细胞及大鼠肥大细胞蛋白酶1(RMCP1)在大鼠心肌梗死后心肌纤维化中的作用。

Results Fibronectin existed in dental pulp and predentin, and also in space between the wall of dentinal tubule and process of odontoblast in mature dentin. They were mostly distributed in odontoblast layer and round blood vessels and nerves.

结果 纤维粘连蛋白免疫反应普遍存在于牙髓、前期牙本质和成熟牙本质的牙本质小管与成牙本质细胞突起,以成牙本质细胞层,牙髓血管与神经周围最为丰富。

Most of these non-lipogenic elements appear like fibrosarcoma or MFH, and often display features of high grade sarcoma. Sometimes, the sarcomatous elements are that of a low grade fibrosarcoma (consisting exclusively of spindled cells).

大部分非脂肪肉瘤成分镜下很像纤维肉瘤或恶性纤维组织细胞瘤,并且通常显示的是高级别肉瘤的特征。

DATA SYNTHESIS: Sixteen experiments discussed the relationship between the fetus and scarless healing on terms of growth environment, inflammation reaction to trauma and regulation of fibroblast in organism, extracellular matrix and nany cellular factors.

资料综合:16个实验从胎儿的生长环境、对创伤的炎症反应、肌体内纤维母细胞及细胞外基质、以及众多细胞因子的调节等等方面寻找其与无瘢痕愈合的关系。

Methods The changes of contents of AGEs in plasma and the abdominal aorta and changes of VSMC of the abdominal aorta were investigated with methods of fluorospectrophotometry, immunohistochemistry, computer image analysis and transmission electron microscopy on streptozotocin-induced diabetic rats. Results From the fourth week, in diabetic rats, the contents of AGEs in plasma and the abdominal aorta increased, the relative area of α-SM-actin in the abdominal aorta decreased, the density of nucleus of VSMC increased, and mitochondria and rough endoplasmic reticules in VSMC increased.

后者在早期主要是血管平滑肌细胞(vascular smooth muscle cell, VSMC)和胶原纤维增多,弹性纤维减少,动脉增厚等,引起动脉的顺应性降低,舒张功能减弱[1~3];晚期主要表现为动脉粥样硬化和动脉硬化,其中以VSMC的增生和迁移较为突出,其表型也由收缩型转化为合成型[4,5]。

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