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Abstract] objective to study the pathological features and histopathological type and differential diagnosis of hepatic focal nodular hyperplasia.methods the clinicopathological characteristics of 40 cases of fnh were studied.all were evaluted by use of paraffin embedded sections and he staining before light microcope observation.results there were 28 females and 12 males fnh patients whose age were from 16 to 62 years(median 41.3),all alpha-fetoprotein was negative and had no hepatitis history.25 cases were classic type showed characteristic central stellate fibrotic scar,composed of fibrous connestive tissue and tortuous blood vessels.8 cases were telangiectic type,the left were mixed type and adenomatoid type.conclusion fnh is a reactive proliferation of hepatic cells to local blood vessel anomalies,it is not realy a tumor.its differential diagnosis includes hepatic adenomatous hyperplasia nodule,hepatic anaplasia nodular hyperplasia,fibrolamellar hepatocellular carcinoma and hepatocellular adenoma.

目的 探讨肝局灶性结节性增生的病理形态特点、组织分型及鉴别诊断。方法分析40例肝局灶性结节性增生的临床资料,并采用石蜡包埋he染色光镜下观察其组织学特点。结果 40例肝局灶性结节性增生患者中,女28例,男12例,年龄18~62岁,平均年龄41.3岁,所有病例术前均无肝炎病史,甲胎蛋白阴性,组织学上25例为经典型,有特征性的中央纤维瘢痕,由纤维结缔组织及扭曲血管组成。8例为毛细血管扩张型,其余为混合型及腺瘤样增生型。结论肝结节性增生是一种肝细胞对局部血管的异常反应性增生,并非真性肿瘤,主要与肝腺瘤样增生性结节、肝间变性结节状增生、肝纤维板层癌及肝细胞腺瘤鉴别。

It is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan , and elastin fibers.

它是专门组成所谓的软骨细胞以及产生大量细胞外的基质所组成的胶原纤维,含有丰富的蛋白多醣物质,以及弹性纤维。

They can increase the body's microcirculating blood, activate the histiocyte, effectively regulate the nervous system, unclog the meridian, enable the body to produce heating effects and improve sleeping quality; Moreover, the negative ion density of the bamboo fiber is up to 6000 per cubic centimeter, equal to the negative ion density content of the suburban fields, making people feel refreshing and comfortable.

竹纤维含有多种人体必需的氨基酸,-皮肤具有独特的保健功能;竹纤维素-竹密、果胶具有滋润皮肤和抗疲劳的-功效;竹纤维不带自由电荷,抗静电-止瘙痒;竹纤维制品质地柔软,亲和-肤,能改善人体的微循环血流,激活-组织细胞,有效调节神经系统,疏通-络,使人体产生温热效应,改善睡眠-量,此外,竹纤维中负离子浓度高达- 6000个/立方厘米,相当于郊外田野的负-离子浓度含量,使人倍感清新舒适,-以说是"家中相伴,在绿色竹林中徜-每一天"。

Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.

结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩,管壁增厚呈空虚网状,生精细胞层次减少,间质细胞增生,但仍见有精子生成;高剂量组可见到精子呈异型性改变,细胞核浓缩深染,且随着摄入时间延长改变愈趋明显;F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩,间质增生明显,20个月时肾小球萎缩纤维化;F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生,淋巴母细胞增生活跃,20个月时脾小体减少,生发中心稀疏;F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润,晚期骨髓有核细胞减少,脂肪细胞增加。

In treatment group, there was no progressive necrosis in stasis zone, and at 24 h post injury, capillary dilation, cell edema and inflammatory infiltration were lessened significantly. In control group, 2 wounds had progressive necrosis (accounted for 10% of the total). Cell edema, inflammatory infiltration and capillary thrombosis were serious, Until 72 hr post injury, cell edema did not subside and necrosis of the dermis worsened. 2. Pathological assessment of the stasis zone tissue: As compared with that in control group, in treatment group the dermis structure in stasis zone was intact and the collagenous fiber bundle was normal.

结果:①创面细胞形态学改变:伤后8h毛细血管扩张、细胞水肿,炎性浸润最明显;治疗组中央淤滞区无进行性坏死,伤后24h后毛细血管扩张、细胞水肿、炎性浸润减轻;对照组2个创面呈进行性坏死(占10%),中央淤滞区细胞水肿、炎性浸润明显,毛细血管血栓形成,伤后72h水肿仍明显,真皮坏死加重;②淤滞区组织病理学评分:治疗组与对照组相比,治疗侧淤滞区的表皮结构相对完整、胶原纤维束相对正常,粒细胞浸润小于5个/400倍视野。

ERK positive cell mainly distributed at nucleus of solitary tract, ambigous nucleus, and positive fibers and cells mainly distributed at medullary visceral zone, nucleus of solitary tract and ambigus nucleus. These positive cells formed an isolated zone from nucleus of solitary tract via medullary visceral zone to SP5, which could be seen using immunohistochemical stain. Positive cells and fibers also distributed at the projection from pneumogastric nerve to the stem.

免疫组织学染色可见,阳性细胞主要分布于延髓内脏带的孤束核和疑核、阳性纤维伴随阳性细胞分布于延髓内脏带的孤束核区和疑核、呈沿孤束核经延髓内脏带至三叉神经脊束核的弧行带;在迷走神经向脑干投射部位也可见阳性胞体和纤维的分布。

Most endothelial cells fell off, elastic fibre autolyze; the number of SMC decreased, some SMC nucleus contracted completely or depressed, typical apoptosis body were seen in later stage, muscle silk autolyzed and disappeared mostly; in outer layer saw much collagenic fiber, arranged unorderly; inflammation cells were seen in the aneurysm wall(hypertrophy cell et al.).

多数瘤壁的内皮细胞溶解脱落,不连续,弹力纤维自溶;动脉瘤血管壁均可见SMC明显减少,较多SMC染色质边聚、固缩,部分SMC核全部固缩或出现不规则凹陷,SMC核胞浆或胞核部分出现脱落或裂解成碎片,晚期可见典型的凋亡小体出现,肌丝大都自溶消失:外膜可见大量的胶原纤维,排列较紊乱;瘤壁还可见炎性细胞浸润。

Objective To investigate the characteristics of bone benign fibrous histocytoma, nonossifying fibroma and metaphyseal fibrous defect.

目的 探讨骨良性纤维组织细胞瘤、非骨化性纤维瘤及干骺端纤维性缺损的特殊表现。

Results Myoid/myofibroblastic differentiation occurred most commonly in fibrosarcomatous DFSP. It was recognized histologically as peripherally distributed or randomly scattered small eosinophilic nodules or short bundles, which were composed of bland spindle cells, closely resembling smooth muscle cells or myofibroblasts.

结果 肌样/肌纤维母细胞性分化多出现在纤维肉瘤型DFSP中,表现为肿瘤周边部或肿瘤内散在性分布的深嗜伊红色小结节或短条束,由梭形细胞组成,细胞多无异型性,核分裂象也罕见,形态上似平滑肌细胞或肌纤维母细胞。

Results Histologically, the tumor was composed of mildly cellular benign-appearing spindle-shaped cells and bands of hyalinized collagen in varying proportions from area to area, and a typical patternless archite...

结果镜下见肿瘤组织由不同比例的纤维母细胞和胶原构成,纤维母细胞分化良好,形态多样,散乱穿梭于胶原蛋白束之间或环绕在玻璃样变的血管周围,伴有局灶性致密区域;胶原成分发生玻璃样变,局部呈轮辐状或瘢痕状排列。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。