纤维细胞的

The collagen is main component in dermis, it is about 70% net weight of dermis .

成人皮肤中的胶原纤维主要是Ⅰ型和Ⅲ型胶原蛋白组成，这些均由成纤维细胞分泌。

Aggressive fibromatosis is a disease of benign ,clone hyperplasia of fibrocyte.β-catenin,which starts downstream gene transcription,was found concentrated in cell nuclei in sporadic patients.

侵袭性纤维瘤病是一种良性克隆性纤维细胞增生疾病，在散发病人的组织病理切片中发现β-catenin向细胞核内浓聚，即向核内转移启动下游基因转录。

STAT1 may be important in the process of CTGF-induced proliferation and differentiation of hHSFB.

STAT1可能在CTGF促进人增生性瘢痕成纤维细胞增殖和分化过程中可能发挥着重要作用，以上研究结果为抑制瘢痕纤维化及挛缩提供了新的研究方向。

Cell lines was established in vitro cell culture system. Only one of it grows well during gene targeting operation. The sex of these cell lines was identified by Sry-PCR.Using lipotransfection method to transfer pZJ into pig fetal fibroblast cell. After 7 days G418 selection, 30 neo-positive cell clones were obtained, among them, 12 of which is non-green ones.

用Sry-PCR法和染色体核型分析法鉴定细胞系的性别，采用优化的脂质体转染法将pZJ转染猪胎儿成纤维细胞，经7天G418(600μg／ml)药物筛选，共获得30个neo阳性细胞克隆，其中12个为非绿色细胞克隆，仅有7个可以扩大培养。

AIM: To study the expression of MMP2 and MMP9 in fibroblasts of rat silicotic fibrosis model and its significance.

目的：探讨肺间质成纤维细胞MMP2和MMP9在SiO2致肺纤维化中的表达及意义。

JC| o tl9^4M AIM: To study the expression of MMP2 and MMP9 in fibroblasts of rat silicotic fibrosis model and its significance.

O8R-gr1STXj，Z 目的：探讨肺间质成纤维细胞MMP2和MMP9在SiO2致肺纤维化中的表达及意义。

The injured gill cells had a different ultrastructure, with endoplasmic reticulum dilated and vesiculated, mitochondrial cristaes partially disintegrated, gill fibre cuticles denatured and dropped. The ultrastructural damages to hepatopancreatic cells were characterized by the decrease of microvilli, swelling and breaking up of mitochondria, expansion of endoplasmic reticulum, disruption and vacuolization of nucleus, tumefaction of nuclear membrane and increase of lipid droplets. As for the toxicological changes of myocardial cells, the mitochondria were swelling, having a lot of vacuolus and disintegrating, while the myofibrils were irregular with endoplasmic reticulum dissolved.

鳃细胞的损害表现为鳃丝水肿，细胞器溶解，角质层变薄，线粒体、内质网的肿胀、解体；肝胰脏细胞的主要损害特征为肝管微绒毛减少，线粒体水肿解体，内质网扩张，细胞核空泡化，核膜水肿和脂肪滴增加；心脏细胞的毒理变化为线粒体内嵴肿胀、瓦解，肌原纤维不规则，内质网溶解。

In a word, mad1 gene or mad1 combining with c-myc gene could inhibit TCCB cell proliferation but not normal fibrocytes in vitro and in vivo, which targeted hTERT, suppressed its transcription and expression, and down-regulated the expression of cyclin D1 and TGF-β1, to further block the cell cycle, change cell morphology and suppress proliferation.

综上所述，mad1基因或mad1联合c-myc基因能在体内外抑制TCCB细胞的增殖，但对正常成纤维细胞无明显影响，二者以hTERT为作用靶点，抑制其转录和表达，并下调cyclin D1和TGF-β1的表达，进而阻止细胞周期、改变细胞形态和抑制癌细胞的增殖。

Mouse fetal tissues could be cut into uniform small pieces by scissors cutting and needle grinding, which grew well in tissue culture and great amounts of cells grew from the attached small tissue clump to form primary mouse embryonic fibroblasts monolayer.

将这些组织块培养48h，大量的梭形细胞从贴壁小组织块的边缘游离出的，细胞密度大，细胞生长旺盛，很快形成原代小鼠胎儿成纤维细胞单层。

In the present study, CHL cells were cultured routinely in MEM medium for 3 days. Then the cells were treated with sham exposure , 0.4mT 50 Hz sinusoidal MF , 0.4mT noise MF and the combined noise and 50Hz MF for 3 min and 15min, respectively. After exposure, the cells were lysed, and the proteins were extracted.

实验中，将中国仓鼠肺成纤维细胞分别经0.4mT工频磁场、等强度的噪声磁场、工频磁场与噪声磁场的复合磁场辐照及假辐照处理3min和15min后，裂解细胞，提取细胞蛋白质，以Western印迹技术，测定并比较细胞内SAPK磷酸化的变化。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。