纤维细胞的

At 8 weeks postoperatively, the grafts were mostly substituted by new cells, and the artificial ligament was completely parceled by the synovial membrane, but there were still some gaps; The combined tendon exhibited no loose or disfiguration, the infiltrative inflammatory cells disappeared. The cells in grafts were close to normal cells in anterior cruciate ligament, but fibrocytes arranged in disorder and fibers showed a verticality.

移植后第8周，移植物大部分组织被新长入的细胞替代，人工韧带被滑膜完全包裹，浸润的炎症细胞基本消失，部分接触面已融合，但部分面仍有间隙；联合肌腱无变形和松弛，移植物内细胞形态，数量接近正常前交叉韧带，但纤维细胞排列杂乱，纤维有了一定的纵向性。

HPMCs from effluent derived of patients undergoing CAPD had markedly varied morphologic features, ranging from a cobblestone-like appearance similar to that of mesothelium derived from omentum to fibroblast-like cells or mixed cell populations.

2相差倒置显微镜观察新开管的患者腹透流出液培养的HPMCs形态上一小部分呈圆形，椭圆形的上皮样细胞，融合后呈铺路石状，与大网膜培养的腹膜间皮细胞相似；而大部分为上皮样细胞和梭形的纤维样细胞的混合存在；腹透一年以上的患者腹透流出液培养的HPMCs多为梭形的纤维样细胞。

By the cooperation of 8-MOP/UVA, the photoaging-characteristic biological markers of the dermic fibroblasts in vivo and in intro were changed as follows:① with a permanent switch of mitotic to stably postmitotic phentypes, fibroblasts displayed growth suppression and morphological changes of cell senescence;② increasing expression of SA-β-galactosidase;③ increasing expression of p16 protein;④ continuous up-regulation of mRNA of MMP-1 and MMP-3, while the protein of TIMP-1 was only slightly induced;⑤ high levels of the 4977bp deleted mtDNA accumulated in dermis and cultured fibroblasts, and large accumulation of a A→C base transversion of 414 position of 〓 of human mtDNA control region for replication of cultured fibroblasts also.

2.8-MOP/UVA作用下，体内外真皮成纤维细胞生物学特性出现具有光老化特征性的改变：①细胞由具有分裂活性的分裂表型转化为不具有分裂能力的分裂后表型，形态学出现细胞衰老的相应改变；②SA-β-Gal表达增加；③p16蛋白表达增加；④MMP-1、MMP-3 mRNA持续表达而TIMP蛋白表达仅被轻微诱导；⑤mtDNA 4977bp缺失大量累积，培养成纤维细胞mtDNA复制控制区〓片段414碱基迅速出现大量A→C的点突变。

What was observed under a light microscope included: tumor cells were mulberry and micropapillary shaped or were of glandule tubular arrangement; there was obvious interspace between cancer nest and neighboring areas; micropapillary was empty of fiber blood vessel axes, with micropapillae floating freely in spongy spaces and separated by fibrous septa.

光镜下特征性表现为肿瘤细胞呈桑椹状、微乳头状或小腺管样排列，癌巢与周围间质形成明显的空隙，微乳头缺乏纤维血管轴心，每个微乳头细胞团和周边的纤维组织均存在无细胞的间隙样结构；瘤细胞CerbB-2、CgA和EMA。

4The Masson trichrome stain can be used for an important method for the observation of the fibrostic cells, The changes of the mast cell could be considered as an assist marker for the observation of the liver fibrogenesis.In addition the concentration of the hepatic hydroxyproline could be used for diagnosis of the hepatic fibrosis. clinical and experimental study.

Masson三色染色可以作为肝纤维化肝硬化组织细胞观察的一种重要方法：肝纤维化过程中，肥大细胞数量的动态变化，可以作为观察肝纤维化变化的一项辅助指标；肝脏羟脯氨酸的浓度变化可以作为肝纤维化的辅助诊断及应用于相关实验的研究。

On the termination date, the cultured explants were all examined by Western blot, HE and transmission electron microscope. Our results showed that after 12-days in culture, the cultivation treated with AS-ODN reduced the synthesis of AMBN and had a deformed dental cusp with thinner enamel matrix. Ultrastructure analyses showed that there was hardly any cisternae of the rough endoplasmic reticulum in the ameloblasts at the tip of the cusp of AS-ODN treatedexplants. However, on average the enamel matrix was thinner compared with that in the control group. Furthermore, the collagen fibers in extracellular matrix were found disorganized. These findings seemed to provide a direct experimental evidence that tended to indicate that the arrested AMBN translation in cultured tooth germs might result in the delay of the tooth development.

经用Western蛋白印迹检测表明，所设计的反义核酸对AMBN InRNA具有良好的封闭效果并成功阻断了牙胚对AMBN的表达；在缺乏AMBN情况下，与对照组相比，实验组牙胚在体外可以继续生长发育至钟状晚期，出现成釉细胞和成牙本质细胞的分化，成釉细胞可以分化成为分泌期型成釉细胞，胞浆中缺少合成蛋白质所必需的粗面内质网和高尔基氏体，缺乏溶酶体，表明对蛋白合成和脚的能力降低；实验组牙胚有牙尖形成和基质分泌，但牙尖形态异常，基质形成减少，牙尖周围基质最厚处为O.6卜m，明显薄于对照组的5.spin，基质中胶原纤维粗细不等，排列稀疏， 3 第四军医大学硕士学位论文未见钙化现象，充分证明了AMBN在牙胚发育中参与釉质基质形成和矿化过程，影响胶原纤维和牙本质基质的合成，促进成釉细胞对蛋白质的合成和釉质基质蛋白降解。

Methods: Fibroblast cell were treated with -300,-500 and -1 000V PTFE electrets for 24, 48 and 72 h, respectively, and the influence of negative electrets on cell apoptosis was studied by means of flow cytometry and transmission electron microscope.

选用-300、-500和-1 000 V PTFE驻极体作用于成纤维细胞24、48和72 h，利用流式细胞仪和透射电子显微镜研究负极性驻极体对成纤维细胞凋亡的影响。

Bone marrow derived fibrocytes migrate to the asthmatic airway from blood circulation acts as a progenitor cell of fibroblast and myofibrolast.

近来研究也发现，骨髓生成的纤维球扮演了纤维母细胞或肌纤维母细胞的前驱细胞角色，在特定细胞激素的引导下，由血流循环中移行至发炎的气道。

The positive expression rates of Tissue Inhibitors of Metalloproteinase-2 protein in the cases of involuting groups were significantly higher than those in proliferating group and vascular malformation groups and normal skin group (P.05). Its difference was significant. Conclusions: Matrix MetallProtinase-2 and Tissue Inhibitors of Metalloproteinase-2 may play an important role in the pathogenesis of hemangiomas through angiogenesis. They may have no effect on vascular malformation and normal skin

血管瘤退化期，TIMP-2表达明显升高，说明 TIMP-2与血管瘤纤维化、消退有关，其机制可能是一方面通过抑制MMP-2介导的基底膜降解而在内皮细胞迁移、聚集中起作用，另一方面直接抑制内皮细胞的增殖及迁移，使内皮细胞高频率调亡，细胞外基质增多，组织出现纤维化，最终导致血管瘤的退化。2、血管畸形和正常皮肤小血管中MMP-2和TIMP-2不表达或表达较弱，说明血管畸形和正常皮肤小血管中并不存在异常的血管生成，据此可以对血管性疾病进行分型、分期，并指导临床治疗。

Following successful modeling, rats of bFGF group were intratracheally injected with 400 U bFGF and rats of VEGF group with 2 μg VEGF, once a week for three times. MSCs group was injected 1 mL suspension of 4×109/L MSCs into tail vein. MSCs+VEGF group was injected MSCs into tail vein and intratracheally injected VEGF (2 ug, three times) at the same time. Model control and normal control groups were intratracheally injected with equal volume of sodium chloride.

成功造模后，碱性成纤维细胞生长因子组气管内注入400 U碱性成纤维细胞生长因子，血管内皮生长因子组气管内注入2 μg血管内皮生长因子，1次/周，共3次；单纯细胞移植组于尾静脉注入4×109 L-1骨髓间充质干细胞悬液1 mL；血管内皮生长因子+细胞移植组气管内注入血管内皮生长因子的同时，尾静脉注入骨髓间充质干细胞；模型对照组、正常对照组给予相同体积的生理盐水。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。