纤维细胞

To solve the problem and improve the safety of gene therapy, we used microencapsule, a insulation tool of cell transplantation immunity, to encapsule human fibroblastlike bone marrow stroma cells transfected by part of CEA gene and produced microencapsulated CEA transgeneic cell vaccines; we also studied the expression of vaccine in mouse body as well as its immunologic characteristics.

为解决上述问题、提高基因治疗的安全性，本研究采用细胞移植免疫用隔离工具-微胶囊包裹转染部分CEA基因的人成纤维样骨髓基质细胞HFCL，制备出CEA微囊化转基因细胞疫苗，并进行了疫苗在小鼠体内的表达及其免疫学性质的研究，探讨该疫苗应用于CEA阳性肿瘤治疗的可能性，并为进一步的临床应用研究奠定了基础。

BACKGROUND: One of the key neuropathological changes in Alzheimer disease is that neurofibrils over phosphorylated cytoskeletal protein composed of entwist together, and the phosphorylation of τ protein can be catalyzed by cyclin dependent kinase 5 (CDK5),however whether the phosphorylation of neurofilaments can be catalyzed by CDK5, as well as its role in the pathogenesis of Alzheimer diseases is less acknowledged.

背景：阿尔茨海默病的主要神经病理学特征之一是由过度磷酸化的细胞骨架蛋白如(o，神经细丝组成的神经原纤维缠结，细胞周期蛋白依赖性蛋白激酶5可催化蛋白的磷酸化，但神经细丝是否可被细胞周期蛋白依赖性蛋白激酶5磷酸化及其在阿尔茨海默病发病中的作用却知之甚少。

MATERIALS: Six adult New Zealand clean rabbits of either gender were included in the present study.METHODS: Tendon sheath fibroblasts, epitenon tenocytes, and endotenon tenocytes were isolated from rabbit flexor tendon and cultured.

目的：探讨兔屈趾肌腱腱鞘、腱外膜和腱内膜细胞增殖、胶原产生和乳酸对细胞的增殖、胶原产生和对转化生长因子β1，基础纤维母细胞生长因子，白细胞介素8分泌的影响。

The nuclei were oval, round without alypia, and rate of mitotic activity was evident1 Psudopapillary structure with a fibrovascular core was remarkable Hemorrhage, foam cells and cholesterol crystals were often found.

肿瘤细胞围绕纤维血管覆层排列形成假乳头突起，常见肿瘤细胞的退变、出血、泡沫细胞和胆固醇裂隙。1例见肝脏内肿瘤组织转移。

Results Among the three groups,the children's rib cartilage had the most blood vessels,the most chondrocytes,well-distributed stain of matrixes,and the type Ⅱ collagen was expressed actively and highest in photedensity.The rib cartilage of teenager group had less blood vessels,unhomogeny distributed stain of matrixes,the enlarged and separated cartilage lacunas.The rib cartilage in adult group showed the least blood vessels,the least chondrocytes.the hyalinization of perichondium,the most deposition of calcium salt,and the type II collagen was expressed at the lowest level in photodensity.

结果 儿童组肋软骨膜血管最丰富，软骨基质染色均匀，软骨细胞数目最多，Ⅱ型胶原蛋白表达最活跃，平均积分光密度值最高；青少年组软骨膜内血管减少，软骨基质染色出现明显的不均质状，软骨陷窝体积变大，并呈分隔状，陷窝内软骨细胞数目减少，II型胶原蛋白表达较儿童组减弱；成人组软骨膜血管、细胞成分明显减少，软骨膜内的纤维成分明显玻璃样变，钙盐沉积较青少年组时明显增多，Ⅱ型胶原蛋白表达较青少年组减弱。

We describe a case of NLPHL showing a variant histologic pattern characterized by small and large clusters of lymphocyte predominance cells within nodules defined by follicular dendritic cell meshworks, associated with numerous neutrophils and areas of internodular fibrosis. Focally, the neoplastic cells had lacunar cell-like cytologic features.

在此，我们描述一例组织形态特殊的NLPHL，其形态学表现为以淋巴细胞为主的细胞排列成大小不等的结节，结节均由滤泡树突状细胞网网罗，结节内见中性粒细胞浸润，部分结节间见纤维化，局灶瘤细胞呈陷窝样。

The ligamentous scaffold material were made from the PVA fibers by braiding technique. The mechanical properties of the scaffold materials were measured using the electronic materials testing machine. Human ACL cells were isolated and cultured by tissue explant and collagenase digestion methods, the morphous characteristics of cells and the secretion of collagen protein were measured. In order to observe the biocompatibility between the material and cells, ACL cells were in vitro expanded and seeded on the scaffold materials.

方法］用聚乙烯醇纺丝纤维编织构建韧带支架材料，在电子拉力机上测试该支架材料的力学性质；用组织块和胶原酶消化培养法在体外分离培养人前交叉韧带细胞并对细胞的生长形态和分泌胶原蛋白的特征进行检测，细胞经体外扩增后种植于编织构建的聚乙烯醇韧带支架材料上观察。

The patho-factor of pulmonary fibrosis is very complex. With the development of cytobiology and molecular biology there are much proof shows PF is a disease induced by multiple factor, multiple organ and multiple cell; and happens between cells and mesenchyma in multiple path.

肺纤维化(pulmonary fibrosis，PF)形成的病理因素十分复杂，近几年细胞生物学和分子生物学的发展为PF的形成机制提供了大量依据，证明PF是一个多因素、多器官、多细胞、多种因子之间以及细胞与间质成分之间形成的一个多层次，多步骤，多通路的疾病。

Cytology revealed 3-dimensional groups of ductal cells in a background of myoepithelial cells and stromal cells, consistent with a fibroadenoma.

对该肿块进行细针抽吸活检，细胞学显示以肌上皮细胞和基质细胞为背景的三维导管细胞结构，与纤维腺瘤结构一致。

To address this question in an unbiased and genome-wide manner, we developed a new method, methylation-specific digital karyotyping, and applied it to epithelial and myoepithelial cells, stromal fibroblasts from normal breast tissue, and in situ and invasive breast carcinomas.

为了能无偏向地并在基因组范围解答这个问题，我们开发了一种新的方法——甲基化特异性数字染色体组型，并将这一方法应用于上皮细胞和肌肉上皮细胞、正常乳腺组织来源的基质成纤维原细胞、原位及侵入性乳腺癌细胞。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。