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纤维细胞

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The unscheduled DNA synthesis of cells was assessed using autoradiography.

用4-NQO处理后,这3种细胞的UDS均呈明显的剂量依赖关系,但气管和鼻咽上皮细胞UDS平均分别是纤维母细胞的3.0和2.4倍。

During fibrosis the hepatic stellate cell undergoes a complex actiation process characterized by increased proliferation and extracellular matrix deposition.

在纤维化过程中,肝星状细胞经历了一个复杂的过程,以细胞增殖和细胞外基质沉积增加为特征。

Methods: The telomerase activity in breast cancer cells and MRC-5 cell line were detected semi-quantitively by TRAP-ELISA assay. Virus proliferation as- say and cell viability assay were used to evaluate the proliferation and cytolysis selectivity of CNHK300, and the results were compared with those of wtAd5. The breast cancer cells were treated with CNHK300 combining paclitaxel to evaluate the killing effect of the combined regimen.

用TRAP-ELISA方法检测乳腺癌细胞株(MDA-MB-453、SK-BR-3)和正常成纤维细胞株MRC-5的端粒酶活性;进行病毒增殖实验和细胞生长抑制实验,并与野生型腺病毒wtAd5进行对比,验证CNHK300选择性复制和选择性杀伤能力;用细胞生长抑制实验进一步考察CNHK300与化疗药物紫杉醇联合应用对乳腺癌细胞的杀伤作用;用Western blot检测腺病毒E1A在细胞中的表达。

In normal group and sham lesion group, BDA positive neurons were distributed symmetrically in the pyramid cells of sensorimotor cortex, and BDA positive fibers of pyramid cells passed through the cerebral cortex, internal capsule, cerebral peduncle of midbrain, basilar portion of pons to the pyramid of medulla oblongata. At the lower part of the medulla oblongata, most of the BDA positive fibers passed through the pyramidal decussation to the contralateral side, continously descended at the ventral part of posterior funiculus just dorsal to the posterior gray commissure and ended at sacral spinal segments.

正常组和假损伤组大鼠BDA示踪显示BDA标记阳性细胞定位于双侧感觉运动皮层的锥体细胞,锥体细胞发出的BDA阳性纤维束对称分布于双侧皮层、内囊、大脑脚、脑桥基底部、延髓锥体中的皮质脊髓束内,继而经锥体交叉到脊髓后索,在双侧后索最深层、灰质后连合背侧下行至脊髓骶段。

Corn's mature thrum wall is only left over 1 epidermal cell, the endothecium, the intermediate deck and the fabric carpet veneer cell disintegrates, its epidermal cell possible fibrosis.

玉米的成熟花药壁只剩下1层表皮细胞,药室内壁、中层和绒毡层细胞均解体,其表皮细胞可能纤维化。

Evodiamine ; mouse fibrosarcoma L1929; cell apoptosis ; cell cycle

吴茱萸碱;小鼠纤维肉瘤 L929细胞;细胞凋亡;细胞周期

Under transmission electron microscope, cellular swelling in brain tissue, nuclear membrane of neuron has incisures, some chromatic agglutination, group A mainly appears endoplasmic reticulum distention and glial cell endocytosis, while group B mainly appears histolysis; cardiac fibrous structure is chaotic, Z line concentrates, mitochondria swelling, nucleus deform; the ecphyma of podocyte becomes thinner and longer like villus, some mix together, plasma membrane infolding of renal cells decreases, mitochondria malformation, cells in lumens.

透射电镜观察显示,试验组动物脑组织细胞肿胀,神经元核膜出现切迹,部分染色质凝集,A组动物出现内质网扩张及胶质细胞吞噬现象,B组动物以组织溶解为主;心肌纤维结构紊乱,Z线聚集,收缩带形成,线粒体肿胀,核变形;肾小球足突细长,绒毛化,并可见足突融合,肾小管上皮细胞质膜内褶减少,线粒体畸形,管腔可见脱落细胞,上述改变均以B组为著。

In general, asbestos fibres are thought to act through direct physical interactions with the cells of the mesothelium in conjunction with indirect effects following interaction with inflammatory cells such as macrophages.

一般来说,石棉纤维被认为是通过直接的行为相互作用物理与细胞的皮与间接影响下面的互动与炎性细胞如巨噬细胞。

Thimerosal Induces DNA Breaks, Caspase-3 Activation, Membrane Damage, a n d Cell Death in Cultured Human Neurons a n d Fibroblasts

硫柳汞诱发DNA突变,激活Caspase-3,膜损伤,细胞死亡,在人类神经和纤维原细胞培养中的细胞死亡

Varying degrees of thickening in gallbladder wall and straw-colored or brown-yellow plaque or node in cross-section can be seen, some with pedicle swelling like polypus, normal structure of gallbladder wall is found to have bean damadged microscopically, replaced by characteristic yellow granulomatous structure, consisting of plenty of foamy cells, acute and chronic inflammatory cells, fibroblasts, foreign-body giant cells and Touton cells.

大体观察胆囊壁不同程度增厚,切面常见淡黄色大小不等的结节或斑块,有的有蒂呈息肉样隆起。镜下见胆囊壁的正常结构受到破坏,代之以特征性黄色肉芽肿性结构,由大量泡沫样细胞、急慢性炎细胞、纤维母细胞、异物巨细胞及Touton细胞等组成。

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