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纤维细胞

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The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma; therefore, a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy.

对於病理医师和临床医师来说,区分出这个纤维神经瘤的变异型非常重要,因为异生细胞纤维神经瘤在组识学上和细胞学上都非常类似肉瘤,因此正确的诊断出这个纤维神经瘤的变异型是必要的,因为临床上对於良性和恶性肿瘤的治疗和肿瘤行为表现是不同的。

The recognition of this entity is of great importance to both pathologists and clinicians because atypical cellular neurofibroma is clever at masquerading both histologically and cytologically as a sarcoma therefore , a precise diagnosis of this variant is essential because of the differences in treatment and clinical behavior between benignancy and malignancy .

对於病理医师和临床医师来说,区分出这个纤维神经瘤的变异型非常重要,因为异生细胞纤维神经瘤在组织学上和细胞学上都非常类似肉瘤,因此正确的诊断出这个纤维神经瘤的变异型是必要的,因为临床上对於良性和恶性肿瘤的治疗和肿瘤行为表现是不同的。

Resulte: In 12 infective lesions, including purulent infection (4 cases) and tuberculosis (8 cases), the correct dignosis was made in 4cases by CR and in 11 cases by CT. In 16 soft tissue tumors, including lipoma (7 cases), fibrosarcoma (4 cases), hemangioma (1 case), neurofibroma (1 case), malignant fibrous histocytoma (1case), aggressive fibromatosis (1 case) and liposarcoma (1 case), the correct diagnosis was made in 3cases by CR and in 14 cases by CT. In 11 bone lesions, including fibrous dysplasia (7 cases), chondroma (2 cases), myeloma and cosinophilic granuloma (1 case), the correct diagnosis was made in 8cases by CR and in 10 cases by CT.

结果:感染组12例中(包括化脓性感染4例,胸壁结核8例),CR准确诊断4例,CT诊断11例;软组织肿瘤组16例中(包括脂肪瘤7例,纤维肉瘤4例,血管瘤、神经纤维瘤、恶性纤维组织细胞瘤、侵袭性纤维瘤病和脂肪肉瘤各l例),CR准确诊断3例,CT诊断14例;骨肿瘤和肿瘤样病变组11例中(包括骨纤维异常增殖症7例,软骨瘤2例,多发性骨髓瘤和骨嗜酸性肉芽肿各1例),CR准确诊断8例,CT诊断10例。

Anatomy Any threadlike fiber or filament, such as a myofibril or neurofibril, that is a constituent of a cell or larger structure.

原纤维:任何如肌原纤维或神经纤维等的线状纤维或丝,是细胞或大一些的结构的组成部分

MATERIALS AND METHODS: Arg to Ser mutation was introduced into the 249 position of the p53 gene by knock-in method. These ES cells with this mutation were selected according to the homologues-recombination with PCR and Southern blot. The positive ES cells without a selection marker were injected into blastocysts recovered from Hprt(superscript -/-) mice, which were derived from Hprt-deficient ES cells. The injected blastocysts then were implanted into pseudopregnant females.

材料与方法:利用基因打靶技术在小鼠胚胎干细胞p53基因249编码子中引入点突变,使编码子249由精氨酸变成丝氨酸,然后将含突变的ES细胞显微注射到Hprt小鼠囊胚中,将注射过的囊胚植入假孕的雌性小鼠子宫,到第14d取小鼠胚胎纤维母细胞,用含HAT的培养液筛选出从ES细胞分化而成的鼠EF细胞,经测序证实细胞含有由249Arg到Ser的突变。

In electricity plus thermal group, the pathologic alterations were slighter than model group; there was little crack on the surface of cartilage, with intact collagen fiber structure and less pyknotic chondrocytes. Although some chondrocytes shrank, there were intact cell organs in many chondrocytes even chondrocyte cluster in some regions.

疏密波+热软膜组在病理程度上的改变明显轻于模型对照组,软骨表面裂纹少,胶原纤维结构基本完整,固缩的软骨细胞少,虽可见部分退变的软骨细胞,但部分软骨细胞具有较多的细胞器,某些区域形成软骨细胞簇。

Results: The positive results of in-situ hybridization showed that the lung tissues of all cases expressed SARS-CoV RNA, and positive signals displayed in cytoplasms (purple-blue, NBP-BCIP.

原位杂交和免疫组化结果显示:支气管上皮细胞、Ⅱ型肺泡上皮细胞、血管内皮细胞、巨噬细胞、纤维母细胞及T淋巴细胞在所有SARS病例中都受到了病毒感染。

ISH-IHC double staining showed that positive signals of both ISH purple-blue NBT-BCIP and IHC (red-brown,AEC expressed in the cytoplasms.

原位杂交和免疫组化结果显示:支气管上皮细胞、Ⅱ型肺泡上皮细胞、血管内皮细胞、巨噬细胞、纤维母细胞及T淋巴细胞在所有SARS病例中都受到了病毒感染。

There were many acidophil corpuscles in hepatic sinus.

Subacute severe hepatitis 1 肝细胞水肿,肝细胞亚大块坏死,纤维组织紊乱,肝窦内见许多嗜酸性小体,肝细胞及毛细胆管淤胆明显,肝细胞部分脂肪变性,汇管区充血,有炎症细胞浸润

There were many acidophil corpuscles in hepatic sinus.

Subacute severe hepatitis 1 肝细胞水肿,肝细胞亚大块坏死,纤维组织紊乱,肝窦内见许多嗜酸性小体,肝细胞及毛细胆管淤胆明显,肝细胞部分脂肪变性,汇管区充血,有炎症颈椎病细胞浸润

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