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纤维细胞

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Cells in EGL are generated after birth. In contrast Purkinje neurons are born before birth, which receive main innervations of climbing fibers from the inferior olivary nucleus and parallel fibers from the internal granule cells.

与浦肯野氏神经元在出生前产生这一点不同的是,EGL中的细胞在出生后产生,它们接受从前脑olivary核团发出的攀援纤维的主要神经投射,以及从内颗粒细胞发出的平行纤维的神经投射。

Results Histologically, the tumor was composed of mildly cellular benign-appearing spindle-shaped cells and bands of hyalinized collagen in varying proportions from area to area, and a typical patternless archite...

结果镜下见肿瘤组织由不同比例的纤维母细胞和胶原构成,纤维母细胞分化良好,形态多样,散乱穿梭于胶原蛋白束之间或环绕在玻璃样变的血管周围,伴有局灶性致密区域;胶原成分发生玻璃样变,局部呈轮辐状或瘢痕状排列。

The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells, especially near the hepatic centrolobular and periportal areas. Ovariectomy decreased ER level and ER mRNA expression significantly (P<0.05). Hepatic ER and ER mRNA concentration were elevated after treatment with estrogen in both ovariectomy and sham ovariectomy fibrotic groups (P<0.05), and the elevation of ER was correlated with a marked decrease in hepatic damage and fibrosis.

5肝脏ERα及其mRNA基因的表达分布于肝细胞及肝脏非实质细胞,特别以肝脏中央静脉和门脉周围为主;卵巢切除减少ERα及其mRNA基因的表达(P<0.05);雌二醇治疗在肝纤维化和卵巢切除大鼠均提高肝脏ER及其mRNA基因的表达(P<0.05),其增加程度与肝脏组织学损伤、纤维化指标的降低程度以及肝脏胶原沉积减少相平行。

RESULTS: The extract of Aml could reduce the abnormally high levels of ALT and AST. Examined by light microscope , the degeneration and necrosis level of hepatocytes and the distribution of collagen fibrosis were markedly increased in the model group. The pathological changes and the c ollagen fibrosis associated with hepatic fibrosis decreased significantly in the prophylactically treated groups.

结果: 蓍草提取物预防给药能降低 CCl 4所致大鼠血清中异常增高的 ALT 、 AST 含量,光镜下观察肝纤维化模型组大鼠肝细胞严重变性、坏死,胶原纤维明显增加,蓍草预防各组大鼠肝细胞病理损伤得到明显改善。

Results The BMC surrounding tumor mass and strands showed multi-layered or dissolution, pseudopodia were seen extended from tumor cells, and contained numerous microvesicles.

瘤细胞伸出伪足样突起,且胞浆内含大量微泡,该处基膜消失,胶原原纤维溶解,肿瘤细胞围绕血管部位的血管基膜增厚,纤维组织增生。

The results are unsure for experimental use;The rabbit's corneas that were removed with upper-half of corneal limbal epithelium lamella and erased the center corneal epitheliums were transparent with intact corneal epithelium;In the approach,the corneal and limbal epitheliums were burned with a cotton swab socked in 1 mol/L NaOH,there were 4 rabbits' corneal stroma happened perforation or ulcer and symblepharon,and the other one presented corneal epithelium phenotype.This is an applicable method to create the pathological model of corneal limbal stem cell total deficiency.

结果表明,处理后4周,全周角膜缘上皮板层手术切除,中央角膜上皮层用1 mol/L NaOH擦除的5只试验家兔角膜表面全部血管化、结膜化,未发生睑球粘连,角膜基质胶原纤维完整未见溃疡、穿孔等病变,细胞印迹学检查为结膜表型,可作为实验性角膜缘干细胞移植的病理模型;全周角膜缘上皮板层手术切除,中央角膜上皮用生理盐水擦除的5只试验家兔,有2只为结膜表型,另3只为角膜表型,观察期内结果不稳定;半周角膜缘上皮板层手术切除,中央角膜上皮层用生理盐水擦除的5只试验家兔,角膜表面透明,全部为角膜表型;直接用1 mol/L NaOH擦除角膜缘和中央角膜上皮的试验家兔,有4只角膜基质胶原纤维断裂、溶解,并伴有严重的溃疡、穿孔、睑球粘连等病变,不能用于移植试验,另1只角膜表面透明,未见结膜和新生血管长入,细胞印迹学检查为角膜表型。

Type II cells were mainly distributed in layer V of cortex. It appeared that these cells receive the CRF immunostaining fibers terminals afferent from other cells rather than synthesize CRF by themselves. It is probable that type II cells receive afferent fibers from both extracortex and type I cells within layers II -III cortex. Considered that Type I cells morphologically are inhibitory interneuron, we presumed that type I in layer II -III could inhibit activity of type II cells in layer V.

CRF阳性Ⅱ型细胞主要分布在皮层第Ⅴ层,形态学特征显示这类细胞更像是接收来自其它神经元的CRF纤维投射而非自身分泌CRF,证据显示Ⅱ-Ⅲ层CRF神经元纤维可进入第Ⅴ层,考虑到皮层的CRF神经元形态上为抑制性中间神经元,这些结果提示Ⅱ-Ⅲ层CRF神经元能够抑制第Ⅴ层神经元的活动。

In nevi, the elastic fibers were preserved between nests and often around individual melanocytes.

痣的细胞巢之间保留有弹性纤维,弹性纤维常围绕在单个黑色素细胞周围。

The effects of gastrodine on the expression of glial fibrillary acidic protein, the transuding amount of lactic dehydrogenase, and the activity of nitric oxide synthase in cultured astrocytes of young rats with lesions caused by simulated cerebral ischemia and reperfusion, were determined in this experiment.

观察天麻素对脑缺血再灌注损伤星形胶质细胞胶原纤维酸性蛋白表达、乳酸脱氢酶漏出量以及一氧化氮合成酶活性的影响。结果:天麻素大、小剂量组GFAP纤维样改变减轻,强阳性反应细胞数减少;LDH漏出量下降;NOS活性减弱。

Incubated with cytochalisin B for 4 hours, F-actin bunddles disrupted, confluent ECs monolayer has a complete detachment from the coverslips. So, there is a suggestion that the F-actin in ECs is essential for endothelial adherence under shear stress.

Northcrn杂交结果表明外源性纤维连接蛋白有促进EC肌动蛋白表达的作用,结合F-actin染色及FN受体染色结果,本文认为用纤维连接蛋白作为细胞种植的促粘附物质有助于内皮细胞粘附结构的形成。

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