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纤维细胞

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On magnification, all tumors have sharp peripheral circumscription and all tumors were confined to the upper dermis,and tumor continuity with the epidermis was noted in some cases.Some basloid aggregations associated with a palisaded alignment of the cells at the periphery of the aggregations can be seen..

镜下可见肿瘤边界清楚,大多位于真皮浅层,部分与表皮相连,可见多数基底样细胞集合,周边细胞核成栅栏样排列,绕以明显的纤维性基质以及纤维母细胞,有时在结缔组织之间可见裂隙。

ERK positive cell mainly distributed at nucleus of solitary tract, ambigous nucleus, and positive fibers and cells mainly distributed at medullary visceral zone, nucleus of solitary tract and ambigus nucleus. These positive cells formed an isolated zone from nucleus of solitary tract via medullary visceral zone to SP5, which could be seen using immunohistochemical stain. Positive cells and fibers also distributed at the projection from pneumogastric nerve to the stem.

免疫组织学染色可见,阳性细胞主要分布于延髓内脏带的孤束核和疑核、阳性纤维伴随阳性细胞分布于延髓内脏带的孤束核区和疑核、呈沿孤束核经延髓内脏带至三叉神经脊束核的弧行带;在迷走神经向脑干投射部位也可见阳性胞体和纤维的分布。

Carbon black particles had propensity to redeposit on the fiber surface or inside the fibers and those redeposited ink particles were very difficult to be dislodged. The redeposition of carbon black particles whose size ranged between 0.5μm and 3μm was the main reason for brightness loss.

水性油墨粒子易于沉积在纤维表面或细胞腔内,而且一旦油墨粒子沉积于细胞腔内便很难被去除,直径在0.5~3μm之间的水性油墨粒子再沉积于纤维表面或内部是导致白度降低的主要原因。

E and Sirus red in supersaturated picric acid solution;the amount of HA in serum was measured with the method of radiative immunity;the quantitative expression of fibrosis factor—TGF、PDGF was measured with the method of immunity histochemistry.Results:Myocardial collagen in model group increased obviously compared with normal group from the results of electron microscope、H.E、Sirus red in supersaturated picric acid solution.

腹腔注射柯萨奇B3病毒建立病毒性心肌炎慢性期心肌纤维化小鼠模型,随机分为模型对照组、通心络低剂量组、中剂量组、高剂量组,并设正常对照组,用药四周后处死动物通过透射电镜观察心肌细胞超微结构;HE染色、苦味酸天狼星红染色观察心肌胶原数量;放免法测定血清透明质酸的含量;免疫组化染色观察致纤维化细胞因子—转化生长因子和血小板衍生生长因子的定量表达。

Methods:Establish the model of myocardial fibrosis in chronic stage of viral myocarditis by injecting CVB3 into Balb/c rats,divide these rats into model group、Tong xin luo low dose group、Tong xin luo medium dose group、Tong xin luo high dose group and set up normal group,after four weeks of giving medicine execute the animals and observe the ultrastructure of myocardial cell with tramission electron microscope,the quantity of myocardial collagen was observed by staining with H.E and Sirus red in supersaturated picric acid solution;the amount of HA in serum was measured with the method of radiative immunity;the quantitative expression of fibrosis factor—TGF、PDGF was measured with the method of immunity histochemistry.

腹腔注射柯萨奇B3病毒建立病毒性心肌炎慢性期心肌纤维化小鼠模型,随机分为模型对照组、通心络低剂量组、中剂量组、高剂量组,并设正常对照组,用药四周后处死动物通过透射电镜观察心肌细胞超微结构;HE染色、苦味酸天狼星红染色观察心肌胶原数量;放免法测定血清透明质酸的含量;免疫组化染色观察致纤维化细胞因子—转化生长因子和血小板衍生生长因子的定量表达。

Most endothelial cells fell off, elastic fibre autolyze; the number of SMC decreased, some SMC nucleus contracted completely or depressed, typical apoptosis body were seen in later stage, muscle silk autolyzed and disappeared mostly; in outer layer saw much collagenic fiber, arranged unorderly; inflammation cells were seen in the aneurysm wall(hypertrophy cell et al.).

多数瘤壁的内皮细胞溶解脱落,不连续,弹力纤维自溶;动脉瘤血管壁均可见SMC明显减少,较多SMC染色质边聚、固缩,部分SMC核全部固缩或出现不规则凹陷,SMC核胞浆或胞核部分出现脱落或裂解成碎片,晚期可见典型的凋亡小体出现,肌丝大都自溶消失:外膜可见大量的胶原纤维,排列较紊乱;瘤壁还可见炎性细胞浸润。

The fibrous capsulae were formed. From the exudate to the collagenous fibrous hyperplasia stage the inflammatory cells were gradually decreased, while the fibroblasts were constantly increased in the pathological tissue of the middle ear.

从渗出期到胶元纤维增生期,中耳病变组织中炎细胞逐渐减少,炎性渗出物逐渐消散,而纤维母细胞始终增生明显。

Objective To report 1 case with cardial malignant fibrohistiocytoma, and discuss its clinical pathological features based on literature review.

目的 报告1例罕见的心脏恶性纤维组织细胞瘤,结合文献复习,讨论心脏恶性纤维组织细胞瘤的临床病理特点。

We hypothesized that MCP-1 may mediate fibrotic remodeling through recruitment of mononuclear cells and direct effects on fibroblasts.

我们由此推测MCP-1可能通过单核细胞的趋化作用以及直接作用于纤维母细胞来介导纤维化心肌重塑。

Results: Compared with sham controls, a progressive hyalinization and thicked wall of coronary arteries; perivascular fibrosis and interstitial fibrosis were observed in SAD rats.

结果:与Sham组相比,SAD大鼠心肌内冠状血管管壁呈进行性增厚、玻璃样变,管腔狭窄,血管周围纤维化和间质纤维化,心肌细胞肿胀、坏死和炎细胞浸润。

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