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纤维组织形成

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The results demonstrated that TGF-β1 can induce phenotypic transition at suitable concentration and time,it plays an important role of local constitution plerosis and cicatrization of human subconjunctival local tissue remodeling after leision.

结论一定浓度和剂量的TGF-β1能显著诱导HTCF表型转化为肌成纤维细胞,在人Tenon囊组织局部组织损伤修复及瘢痕形成中具有重要作用。

Mass morphological observation: Nasal and sinus cavity got clean within 1 to 2 weeks postoperatively. Operative cavity had the De-mucous reaction from 4 to 6 weeks, such as mucous edema, vesicles, granulation tissue, mini-polyps, fibrous hyperplasia, and adhesion or regenerated diseases may appear in this stage.

结果: (1)对鼻内窥镜术腔大体形态学观察:术后1—2周术腔分泌物较多,残余渗血形成干硬血痂,粘膜表面纤维素渗出物形成模样结构,组织粘膜充血水肿;术后4—6周术腔分泌物减少,术腔可见小囊泡、肉芽、纤维结缔组织增生等病变。

Results: Local high temperatures(>70℃)were observed in pig's kidney, liver in vivo. The pathologic changes of target tissues after FEP were necrosis, liquidizatin and fibrosis.

结果:FEP可在活体猪肾、肝等组织内形成一大于70℃的局限性高温区,FEP后靶组织的病理过程为坏死、液化、纤维化。

e-PTFE was implanted into the pitting area after subcuntaneous disjunction. Results: 15 cases were followed for about 3 and 6 momths after implant of e-PTFE, including cases with saddle nose, pitting deformity of orbit, congenital lip cleft with depressed soft tissue around pyriform opening, parbial defect of helix. In these cases, satisfaction rate is evaluated as high as 97.9%, unexpected tissue response was not shown in this clinical trail.Conclusion: Depended on this clinical trail, we believe local e-PTFE manufactured by Shanghai Suo-kang Medical Implants Co., Ltd.

由于e-PTFE的组织相容性好,在80年代初期一些发达国家已经应用于整形美容外科[1],尤其应用于隆鼻术、面部凹陷畸形的整复、唇线增高、唇加厚、鼻唇沟过深的整形美容术、耳廓缺损等手术中,学者们认为e-PTFE排斥反应的发生率低,弹性和硬度与软组织相似,周围组织细胞能够长期进入移植物内,不形成纤维囊,在整形美容外科领域有重要的应用价值。

In this report, immunohistochemistry and in situ hybridization techniques were perfected to examine the expression of bFGF, fibroblast growth factor receptor-I and bFGFmRNA of cultured HEP-2 laryngo-tumor cell and 803 gastro-tumor cell and of the solid tumor tissue formed by implanting the cultured cells into subcutis of nude mice, intending to elucidate the correlation between the expression level and the tumor formation.

本研究建立了免疫组化和原位杂交的检测方法,通过对体外培养的HEP-2喉癌细胞和803胃癌细胞和这两株细胞在裸鼠皮下形成的实体瘤组织中bFGF,纤维细胞生长因子受体-1(fibroblast growth factor receptor-1,FGFR-1)和bFGFmRNA的检测试图揭示三者在体外和体内表达以及与肿瘤形成的关系,从而为这方面的研究提供更多的材料。

The histological findings of the primary tumor and metastatic lymph nodes demonstrated massive cancer cell degeneration such as pycnosis and vacuolation, xanthogranulomatous inflammation and dense fibrosis. The effect of NAC was judged to be grade 2 histologically.

组织学检查发现肿瘤原发灶和转移的淋巴结癌细胞大量退化如核固缩和空泡形成,黄肉芽肿炎以及密集的纤维化,经组织学判定NAC的疗效为2级。

However, the molecular mechanisms underlying premature aging up 8-MOP/UVA are as yet unknown. In our studies, dermis of the non-lesion back skin of vulgar psoriatic patients who had been treated by PUVA and the cultured foetus dermic fibroblasts were selected to be observed.

本课题以PUVA治疗寻常型银屑病患者背部非皮损区真皮及培养的胎儿真皮成纤维细胞为对象,采用HE染色、Verhoeff染色、电镜、酶组织化学、免疫组织化学、原位杂交、流式细胞计数仪、三引物PCR、PCR-SSCP技术及PCR产物直接测序等技术和方法,研究了8-MOP/UVA对皮肤光老化形成的影响及芳维A酸乙酯的拮抗作用。

4Histological examination of the capsular bags: It could be seen in group 4 that a small amount of LECs at the capsular equator proliferated and migrated to the posterior capsule, forming a thin soemmering ring in the periphery of the capsular bags, forming thin fibromembrane which embodied monolay metaplastic fibroblast-like cells in the center of the capsular bags, or with no cells or cortical material in the center of the capsular bags.

囊袋组织学检查:HSV-TK+GCV组可见少量赤道部晶状体上皮细胞(lens epithelial cells, LECs)增殖并向后囊膜迁移,在囊袋外周部形成稀薄的soemmering环,在中央部无细胞和皮质,或仅形成单细胞层纤维膜。

Results: No fiber layer and inflammatory tissues around any inserted implants were founded. New-grown osteoid tissue appeared faster in Bio-Ti implants than pure titanium and matured bone tissues comprise bone trabecula and Haversian canals appeared in 6 weeks, while at least 12 weeks needed to form matured bone tissue in control groups.

结果:所有种植体周围没有发现明显炎症组织或形成纤维层,Bio-Ti种植体组新生类骨组织生长较快,并于6w时已形成含有骨小梁及哈弗氏小管结构的较成熟骨组织,对照组12w时新生骨组织基本成熟。

Consistent findings in lung biopsies of AP patients included endothelialitis of pulmonary vessels, active fibrosis, lymphangitic inflammatory infiltrates rich in plasma cells and histiocytes with or without nodule formation, and fibrinous pleuritis.

这6例肺穿的其他共同特征包括肺血管内皮炎、纤维化、淋巴管炎细胞浸润(其内富于浆细胞和组织细胞,伴或不伴淋巴滤泡形成)、纤维素性胸膜炎。

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