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纤维组织形成

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All 7 cases were characterized by deposition of dystrophic or psammatous calcifications accompanied with chronic inflammatory cells infiltration in the stroma. In some cases, there was formation of germinal centers.

特徵性形态学表现为在胶原化的纤维组织间可见散在的钙化灶或砂砾小体,间质内伴有多少不等的淋巴细胞和浆细胞浸润灶,部分病例中可见生发中心形成。

At the time of infectious enteropathy intestinal bacteria invades biliary system from portal vein. The chronic inflammation and bile duct wall fibrosis hyperplasia are then formed.

在感染性肠病时,肠内细菌从门静脉侵入胆道系统,形成慢性炎症,胆管壁纤维组织增生,使胆管壁缩窄。

Begin from acute edema, hyperplasy and reparative process accompanied by acute inflammation , subsiding edema, scarification and mussy pigment in turn were found in the photocoagulative spots ; CNV begins to emerge 1w after photocoagulation, and continuely develop during 1w~4w, the growth of CNV displayed the most productive during the time of 1w to 2w, while there is no difference between 3w and 4w, From 4w to 12w, fibrous tissue was mainly seen to increase within CNV membrane.

结果1。氪激光光凝后激光斑从急性水肿开始,依次经历急性炎症、水肿消退、斑痕化和色素化的增生修复过程;1w开始形成CNV,1w~4w随时间迁延CNV持续发展,以1w~2w CNV生长最为旺盛,3w、4w之间差异不明显,4w之后至12w主要表现CNV膜内纤维组织增加。2。

Antibodies against col Ⅲ reacted strongly in the entire pterygial stroma. Conclusions Components of ECM are changed in the pterygium: the sub-epithelial connective tissues and vessels are more prominent in the pterygia than in normal conjunctiva tissues, and abnormal fibers are visible only in the deeper subepithelial connective tissues. This study documents the overexpression of LN and col Ⅲ. They may play roles in cellular adherency, migration and angiogenesis. Also this study documents the overexpression of MMP3 which may degrade ECM in the pathogenesis of the pterygium.

结论翼状胬肉组织中ECM的成分较正常球结膜发生改变,有大量的弹性纤维变性、胶原纤维增生及新生血管形成;col Ⅲ在翼状胬肉组织中表达增加,LN及胶原纤维可能对翼状胬肉中血管形成、细胞粘附和迁移及ECM重建起作用;MMP-3在翼状胬肉组织中表达增加,其对ECM成分的降解作用可能有助于翼状胬肉的形成和向角膜中央侵袭。

Microscopically, this bile duct in a case of sclerosing cholangitis is surrounded by marked collagenous connective tissue deposition.

显微镜下可见硬化性胆管炎的胆管被大量的纤维组织包绕而形成了胆管阻塞。

Results The results revealed that the bone defect in the experimental group had excellent repair than that seen in the control and blank group, both bone union and the period of bone mature were earlier than that seen in the control and blank groups. There was fibration in the blank group at 12th week.

结果实验组骨生成情况优于对照组,无论是骨连接发生时间还是骨成熟时间,实验组均较对照组提前2周左右,同期骨生成量也明显多于对照组,而空白组缺损内主要形成纤维组织。

The advantages of dual grafts for bridging defects are as follows:(1) mechanical fixation is better than fixation by a single onlay bone graft;(2) the two grafts add strength and stability;(3) the grafts form a trough into which cancellous bone may be

双侧植骨桥接骨缺损的优点包括:①机械固定作用比单侧贴附植骨更好;②双侧植骨可增加强度和稳定性;③双侧的植骨可形成一骨槽,可在其中压紧松质骨;④与单侧植骨不同,双侧植骨在愈合过程中可防止挛缩的纤维组织危害移植的松质骨。

The adantages of dual grafts for bridging defects are as follows:(1) mechanical fixation is better than fixation by a single onlay bone graft;(2) the two grafts add strength and stability;(3) the grafts form a trough into which cancellous bone may be packed; and (4) during healing the dual grafts, unlike a single graft, preent contracting fibrous tissue from compromising transplanted cancellous bone.

双侧植骨桥接骨缺损的优点包括:①机械固定作用比单侧贴附植骨更好;②双侧植骨可增加强度和稳定性;③双侧的植骨可形成一骨槽,可在其中压紧松质骨;④与单侧植骨不同,双侧植骨在愈合过程中可防止挛缩的纤维组织危害移植的松质骨。

Results Compared with normal group, the normal hepatic lobules in model group were disappeared and fibroplasias and pseudolobule formed.

结果 与正常组比较,模型组大鼠出现肝小叶损害,纤维组织增生,假小叶形成,肝

Marston, MD, from the University of North Carolina School of Medicine in Chapel Hill, and colleagues."Dermagraft is a bioengineered dermal substitute that laboratory data suggest has two principal modes of action. It provides living, human dermal fibroblasts that deposit matrix proteins and facilitate angiogenesis. It also provides a preformed collagen matrix, receptors, and bound growth factors that facilitate the migration of the patients' epithelial cells that close the wound."

Marston医师及同事表示,针对治疗慢性溃疡的生理失能的患者,还需要更多有效的疗法,而人工皮肤就是一种生物工程皮肤代用品,这一项实验室数据显示两种最重要的功能模式,它提供活体人类皮肤纤维组织母细胞,储存母体蛋白质并促进血管新生,另外它也提供预先形成的胶原母体、接受器及束缚成长因子,帮助病患的上皮细胞移动,使伤口愈合。

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