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纤维组织形成

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The operative area was examined with light microscope, electronic microscope, and the proliferating cell nuclear antigenwas detected. Results In CsA group, intraocular pressure was significantly lower than that in NS group(P<0.05), and more functional filtering blebs were observed. Less fibroplasia and proliferative cells, less bioblast and less active caryotin in fibrocyte were found in CsA group than that in NS group. No serious mcomplicaton was found in both group.

结果 环孢霉素A组眼压控制多较理想,与对照组间的差异有统计学意义(P<0.05),大多数形成功能性滤过泡,光镜下见极少量纤维组织增生,电镜下见纤维细胞线粒体少,染色质功能不活跃,增殖细胞阳性率低,与对照组差异有统计学意义(P<0.05),且没有浅前房、视网膜损害等严重并发症。

At 1st, 7th,14th,and 30th day after surgery, filtering blebs, intraocular pressure, cornea and ocular fundus were observed.the operative area was examined with light microscope, electronic microscope, and the proliferating cell nuclear antigenwas detected. results in csa group, intraocular pressure was significantly lower than that in ns group(p<0.05), and more functional filtering blebs were observed. less fibroplasia and proliferative cells, less bioblast and less active caryotin in fibrocyte were found in csa group than that in ns group. no serious mcomplicaton was found in both group.

结果 环孢霉素a组眼压控制多较理想,与对照组间的差异有统计学意义(p<0.05),大多数形成功能性滤过泡,光镜下见极少量纤维组织增生,电镜下见纤维细胞线粒体少,染色质功能不活跃,增殖细胞阳性率低,与对照组差异有统计学意义(p<0.05),且没有浅前房、视网膜损害等严重并发症。

An animal model of benign esophageal stenosis as a result of cauterization is reliable, and it is characterized by inflammatory response, which is replaced gradually by granulation tissue mid fibrosis.

通过局部烧灼的方法可以建立稳定的犬食管良性狭窄模型,其病理表现主要为肉芽组织形成及纤维化。

The formation of excessive fibrous tissue,as in a reparative or reactive process.

纤维变性多余的纤维组织的形成,如在恢复或反应过程中

RESULTS: Four weeks following repair, CT showed that callus formation appeared in coronal skull defects. 3D reconstruction still demonstrated some defects. Hematoxylin and eosin staining displayed defects were fibrous connective tissue, with the presence of chondroid tissues.

结果:修复后4周,冠状位CT显示颅骨缺损区可见骨痂形成,三维重建仍显示有缺损;标本苏木精-伊红染色显示缺损为纤维结缔组织,并有软骨样组织形成,Mallory三色染色标本呈淡蓝色。

BACKGROUND: Fibration and scar formation are major factors for surgical failure following glaucoma filtration. Although there are so many drugs and methods to inhibit scar formation, they are not ideal.

背景:青光眼滤过后,滤过道的纤维化与瘢痕组织形成,是手术失败的主要原因,虽然抑制青光眼滤过术后瘢痕形成的药物和给药方法很多,但多不理想。

What was observed under a light microscope included: tumor cells were mulberry and micropapillary shaped or were of glandule tubular arrangement; there was obvious interspace between cancer nest and neighboring areas; micropapillary was empty of fiber blood vessel axes, with micropapillae floating freely in spongy spaces and separated by fibrous septa.

光镜下特征性表现为肿瘤细胞呈桑椹状、微乳头状或小腺管样排列,癌巢与周围间质形成明显的空隙,微乳头缺乏纤维血管轴心,每个微乳头细胞团和周边的纤维组织均存在无细胞的间隙样结构;瘤细胞CerbB-2、CgA和EMA。

There were more fibroblasts, the collagen increased in model control group. After 30 days, the fibroblasts of model control group were hyperemic, scattered red blood cells could be found, and capillaries were proliferated. Fibrous tissue arranged in rows in the acupotomology intervention group and the blockade control group.

造模后30 d模型对照组成纤维细胞增生,可见红细胞散在分布,有增生的毛细血管;针刀干预组与封闭对照组可见纤维组织排列成行;针刀干预组较其他各组胶原纤维形成减少,瘢痕面积小。

Fig 1 At the experimental side, two weeks after operation (HE ×100) Many pieces of cartilage cells and spindle-shaped mesenchymal cells were found, by light microscope Fig 2 At the experimental side, twelve weeks after operation (HE ×100) Medullary cavity had formed, which contained hemoblasts and adipocytes, but the trabculae was not typical, by light microscope Fig 3 At the experimental side, twenty-four weeks after operation (HE ×100) The typical cancellous bone had formed, by light microscope Fig 4 At the control side, twenty-four weeks after operation (HE ×100) A large part of CXB was degraded, resorbed and replaced by fibrous tissue, but there was'not any new formed bone, by light mocroscope

图1 实验侧术后2周(HE ×100)镜下可见很多软骨细胞条索和团块生成及大量梭形间充质细胞图2 实验侧术后12周(HE ×100)镜下可见有髓腔形成,内含有造血和脂肪细胞,骨小梁尚不典型图3 实验侧术后24周(HE ×100)镜下可见形成典型的松质骨结构图4 对照侧术后24周(HE ×100)镜下可见大部分CXB被降解吸收,为纤维组织替代,无新骨形成

By histological examination, it was found that in HAC group, there were granulation tissue, fibrous tissue and newly formed vessels grew into the pores and the osteoblasts formed osseous trabeculae.

组织学显示在不同阶段,多孔HAC植片标本有肉芽组织、纤维组织和新生血管向微孔中生长及成骨细胞形成的骨小梁。

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