纤维变性的

Oeeki Y reported a method of partial arterialization of portal vein with ileo-colon arteriovenous anastomosis in 1997, he thought this can prevent theliver failure caused by embolism of hepatic artery after liver operation.

但过量动脉血(门静脉内动脉血灌流量达到门静脉正常血流量的一倍以上时)灌流肝内门静脉则对肝脏有害，如导致肝内门静脉分支增宽，内膜纤维变性，以及肝细胞微粒体酶活力的改变。

November 9, 2007 — Researchers say that the integrin-transforming growth-factor beta axis is involved in the development of fibrosis and that by blocking integrin beta 6, pulmonary toxicity can be prevented and possibly even reversed. The promising preliminary results testing the new monoclonal antibody being developed by Biogen Idec were presented at plenary here at the 49th annual meeting of the American Society for Therapeutic Radiology and Oncology.

November 9， 2007—研究者表示，整合素转化生长因子β轴（integrin-transforming growth-factor beta axis）包含於发生纤维变性之中，且藉由阻断整合素β6，可以预防肺毒性甚至逆转；此一大有可为的初步结果检验了由Biogen Idec所发展的新的单株抗体，发表於美国治疗放射暨肿瘤学会第49届年会全体会议中。

Studies on the lier biopsies included assessment of fibrosis, and of steatosis.

肝活检的研究内容包括纤维化的评估和脂肪变性的评估。

The variants are not like the mutations most of us learned about in school--alterations that cause entire genes or series of genes to malfunction and that result in diseases like sickle-cell anemia and cystic fibrosis.

这些变异不同于我们大多数人从学校里了解到的基因突变——一种引起全部基因或者几种基因机能的失常，并导致像镰形血球贫血症和囊性纤维变性之类疾病的变化。

"I think that's probably going to be the way things go; we have to look at ways to improve insulin sensitivity," said Graeme McDonald, MD, senior lecturer at the University of Queensland, Australia. He added that the approach may be able to improve fibrosis in some patients, although this will need to be shown with well-conducted biopsy studies. I think it may not depend so much on the drug, but whether you're achieving with weight loss with some of the drugs like orlistat or even potentially bariatric surgery.

澳洲昆士兰大学资深讲师Graeme McDonald博士认为，这可能会成为未来的治疗方向，我们必须利用这些方法来改善胰岛素的敏感度，这样或许可以改善某些患者的纤维变性，虽然这还需要许多更完整的切片研究，但他认为除了利用像orlistat这类药物，或为患者进行减肥手术来减轻患者的体重之外，并不需要太依靠药物。

Germ-line mutations in the genes hTERT and hTR, encoding telomerase reverse transcriptase and telomerase RNA, respectively, cause autosomal dominant dyskeratosis congenita, a rare hereditary disorder associated with premature death from aplastic anemia and pulmonary fibrosis.

端粒酶逆转录酶的编码基因hTERT和端粒酶RNA的编码基因hTR发生种系突变时，可引起常染色体显性先天性角化不良，这是一种罕见的遗传性疾病，它与再生障碍性贫血和肺纤维变性所致的早产儿死亡具有相关性。

Further analysis of Lsp1 mice may suggest ways to improve wound healing and/or treat fibrotic conditions of skin and other tissue.

通过对LSP1缺乏小鼠做更多的分析研究可能为改善皮肤创伤的愈合开辟了一个新的途径，此外对治疗某些皮肤和其他组织的纤维变性类疾患也有积极的意义。

OBJECTIVE: To observe the effect of acrylamide on the degeneration and regeneration of sciatic nerve medullated fibers following crush injury of C57BL/Ola rat and C57BL/6J (6J) rat.

目的：观察丙烯酰胺对捻挫损伤后C57BL/Ola鼠和C57BL/6J(6J)鼠坐骨神经有髓纤维变性和再生的不同病理过程。

RESULTS: During 10 - 12 weeks, in cuntrol group: The defect area was repaired by white and soft tissue that had no resistance to press. The repaired tissue was still lower than the surrounding articular surface with clear boundary. By histological observation, it was found that the defect was repaired by the mechanism similar to inflammatory reaction and the defect is ultimately filled by the hyperplasia of hyaline degenerative fibrous tissues. In filling group: the defect was repaired by semi-transparent, smooth, textured tissues with polish that had resistance to press as well as elasticity. The repaired tissue was almost similar to the shape of the surrounding cartilage,difficult to be distinguished. After histological observation, it was found that there was no inflammatory reaction, but active hyperplasia of inner bonetissue and cartilage tissues; a lot of osteoid tissues and trabeculation were found. Newlborn cartilage was fused with surrounding cartilage tissue and connected with surrounding tissues.

结果：10～12周，对照组：缺损区由白色、质软、按压无阻抗的组织修复，修复组织仍低于周围关节面，边界仍清晰可辨，组织学以类似炎症反应的机制修复缺损，最终以透明变性的纤维组织的增生来填补缺损部位；填充组：缺损区由半透明状、质韧光滑有光泽，按压有阻抗并有弹性的组织修复，修复组织与周围软骨外形上已基本相似，不易区分，组织学未见有炎症反应的过程，内骨组织和软骨组织增生活跃，并可见大量类骨组织和骨小梁形成，新生软骨和周围软骨组织融合，并与周围组织连接。

Detail Contents: Genetic disorders -- Immune deficiencies -- Breast cancer -- Colon cancer -- Melanoma -- Cystic fibrosis -- Hemophilia -- Liver disease -- Cardiovascular disease -- Muscular dystrophy -- Alzheimer's disease -- Parkinson's disease -- Huntington's disease -- Viruses: the cornerstone of gene therapy -- Viruses are living crystals -- Viral genomes may be RNA or DNA -- Viruses evolved from plasmids -- Viruses know how to infect cells -- The virus as a gene vehicle -- Viruses used in gene therapy -- Ashi DeSilva: a promising start -- Clinical trials defined -- Cells of the immune system -- Adenosine deaminase -- Preliminary research -- Clinical procedure for ADA gene therapy -- The DeSilva clinical trial -- Jesse Gelsinger: down to earth -- Ornithine transcarbamylase -- Preliminary research -- Clinical procedure for OTC gene therapy -- The Gelsinger clinical trial -- The investigation -- Concluding remarks -- Future prospects -- Safer vehicles -- Reducing immune rejection of the vector -- Improved risk assessment -- Redesigning human anatomy and physiology -- Ethics of gene therapy -- The Belmont report -- Clinical trials -- Physiological enhancement -- Cosmetic applications -- Legal issues -- Regulatory agencies -- The Gelsinger legal trial -- International regulation -- Resource center -- Eucaryote cell primer -- Recombinant DNA primer -- The human genome project -- X-linked severe combined immunodeficiency (SCID-X1)-- Alzheimer's disease -- Huntington's disease.

细节内容︰遗传疾病-免疫的缺乏-乳腺癌-结肠癌-黑瘤-囊性纤维变性-血友症-肝疾病-心血管疾病-肌营养不良-早老性痴呆病-帕金森疾病-亨廷顿疾病-病毒︰基础的基因治疗-病毒在活著水晶--病毒的基因可能是RNA或者DNA --病毒从plasmids被逐步形成--病毒知道怎样感染细胞--作为一辆基因车辆的病毒--基因治疗使用的病毒-Ashi DeSilva︰有希望开始-临床试验确定--细胞的这免疫系统-Adenosine deaminase-初步研究-临床程式给埃达基因治疗--这DeSilva临床试验-婕西Gelsinger︰到地球-Ornithine transcarbamylase-初步研究-临床程式给OTC基因治疗-- Gelsinger临床试验-调查-达成评论-前景-更安全的车辆--矢量的降低免疫的拒绝-改进风险估计-重新设计人解剖学和生理学--伦理学的基因治疗-那些贝拉蒙特报告-临床试验-生理提升-美容应用-法律问题-协调机构-- Gelsinger 合法审讯-国际管理-资源中心人物-Eucaryote信元第一-Recombinant DNA 入门--人类基因工程-- X 连结的严重的结合的免疫缺陷(SCID-X1)-早老性痴呆病--亨廷顿的疾病。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。