纤维原细胞

The adventitia is the outermost layer of the artery and typically consists of a loose matrix of elastin, smooth muscle cells, fibroblasts, and collagen.

动脉外膜是动脉的最外层，典型上，包含了疏松的弹力蛋白基质、平滑肌细胞、纤维母细胞、以及胶原。

But when passing the age of 20~25, the productive rate of making collagen by main cells in derma will decrease. Consequently, the skin will turn loose and wrinkles will show out when the collagen produced is less than it lost.

但自20～25岁后，真皮层中制造胶原蛋白的纤维母细胞制造能力会逐渐降低，当胶原蛋白的制造赶不上流失的速度时，肌肤就开始出现松垮或皱纹现象。

The process of EMT is induced in epithelial cells to lose its cell-to-cell adhesion and transform to mesenchymal-like cells.

同时，近端肾小管的纤维母细胞亦经类似 EMT 之机制而转变成纤维原母细胞，此也是造成肾病变的因素。

E and Sirus red in supersaturated picric acid solution;the amount of HA in serum was measured with the method of radiative immunity;the quantitative expression of fibrosis factor—TGF、PDGF was measured with the method of immunity histochemistry.Results:Myocardial collagen in model group increased obviously compared with normal group from the results of electron microscope、H.E、Sirus red in supersaturated picric acid solution.

腹腔注射柯萨奇B3病毒建立病毒性心肌炎慢性期心肌纤维化小鼠模型，随机分为模型对照组、通心络低剂量组、中剂量组、高剂量组，并设正常对照组，用药四周后处死动物通过透射电镜观察心肌细胞超微结构；HE染色、苦味酸天狼星红染色观察心肌胶原数量；放免法测定血清透明质酸的含量；免疫组化染色观察致纤维化细胞因子—转化生长因子和血小板衍生生长因子的定量表达。

Methods:Establish the model of myocardial fibrosis in chronic stage of viral myocarditis by injecting CVB3 into Balb/c rats,divide these rats into model group、Tong xin luo low dose group、Tong xin luo medium dose group、Tong xin luo high dose group and set up normal group,after four weeks of giving medicine execute the animals and observe the ultrastructure of myocardial cell with tramission electron microscope,the quantity of myocardial collagen was observed by staining with H.E and Sirus red in supersaturated picric acid solution;the amount of HA in serum was measured with the method of radiative immunity;the quantitative expression of fibrosis factor—TGF、PDGF was measured with the method of immunity histochemistry.

腹腔注射柯萨奇B3病毒建立病毒性心肌炎慢性期心肌纤维化小鼠模型，随机分为模型对照组、通心络低剂量组、中剂量组、高剂量组，并设正常对照组，用药四周后处死动物通过透射电镜观察心肌细胞超微结构；HE染色、苦味酸天狼星红染色观察心肌胶原数量；放免法测定血清透明质酸的含量；免疫组化染色观察致纤维化细胞因子—转化生长因子和血小板衍生生长因子的定量表达。

RESULTS: HE stained cells were fusiform-shaped with pseudopodia, round or oval nucleus. The cytoplasm was blue after stained with the toluidine blue. The immunohistochemical test revealed that there existed positive expression of type Ⅰ collagen in the cells. In the presence of 10% calf serum, IGF-Ⅰ significantly improved cell proliferative activity in a dose-dependent manner within effective dose range.

结果：苏木精－伊红染色细胞多为梭形，有伪足伸出，细胞核为圆形或椭圆形；甲苯胺蓝染色，胞浆为深蓝色；免疫细胞学方法检测表明纤维环细胞有Ⅰ型胶原表达；在体积分数为0.1的血清条件下，胰岛素样生长因子Ⅰ能提高细胞的增殖活性，并且在有效浓度范围内呈剂量效应关系。

It suggests that the supraspinous ligaments in the patients with ossification of the ligament flavum also have an obvious tendency of ossification.

结果：胸椎黄韧带骨化症患者棘上韧带内胶原纤维增生、肿胀，出现了大量的纤维软骨细胞，甲苯胺蓝染色呈强异染性。

Patented Matrixyl 盿nd type 3 of collagen of skin. Activate fibrocytes to create more collagen that will make your skin look younger and suppler.

专利成分 Matrixyl 可强化第一型、第三型胶原蛋白，可激活纤维母细胞合成更多的胶原蛋白，使肌肤有弹性。

Patented Matrixyl formula could strengthen the type1and type 3 of collagen of skin. Activate fibrocytes to create more collagen that will make your skin look younger and suppler.

专利成分 Matrixyl 可强化第一型、第三型胶原蛋白，可激活纤维母细胞合成更多的胶原蛋白，使肌肤有弹性。

Matrixyl could strengthen the type1 and type3 of collagen of skin, and then activate fibrocytes by creating more collagen. Therefore, Matrixyl will improve the loose skin and wrinkles at the same time. Make your skin look younger and suppler.

Matrixyl 是专门针对抗皱所设计的专利配方，可使第一型、第三型的胶原蛋白更健全具有支撑力，并激活真皮层中纤维母细胞，促进胶原蛋白增生，改善细纹与肌肤松弛的问题。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐