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纤维原细胞

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Both chrysotile and crocidolite at given dose could stimulate type Ⅰ and type Ⅲ collagen gene expression by 2ES cell, suggesting that asbestos fibre itself may also contribute to collagen gene expression in asbestotic lung 〓.

一定剂量的温石棉和青石棉都可以刺激2BS细胞Ⅰ、Ⅲ型胶原基因的表达,表明石棉纤维本身也是引起石棉肺病变中胶原基因表达增加的重要原因。

As collagen in the meshwork breaks down, it is replaced and repaired by new collagen secreted by fibroblasts.

随着胶原网打破了,这是更换和修理的新的胶原纤维细胞分泌的。

Results Valvular interstitial fibroblasts were most often spindle-shaped in collagen lattice and there was no difference between normal and rheumatic mitral valve tissues.

结果 正常及病变二尖瓣组织来源的成纤维细胞在胶原凝胶中的形态改变差异无显著性,在胶原凝胶内呈长梭形。

The up-regulation of the expression of MMP-9 perhaps takes part in the accrementition and reconstitution of mesenchymal fibers (Ⅰ-type collagen dominates in mesenchymal, IOD ratio ofⅠ/Ⅲchanged). MMP-9 can facilitate inflammatory cell infiltration, aggravate the development of CAM.

2MMP-9的增高可能参与了骨骼肌间质纤维增生及其构成的改变(Ⅰ和Ⅲ型增多,Ⅰ型胶原与Ⅲ型胶原比值增高),诱导炎性细胞浸润,加重慢性酒精中毒性肌病的发生发展。

DESPRIPTION】 This product adopts natural activated Collagen Peptide as its ingredient, and combines the SAYF(skin activate and youthful factor) and micro spinning technology of elastic fiber to make the eye pact perfectly fit around the eye contour, It can quickly supplement skin moisture and provide quick penetration of nutrient substance to the stratum basale under the guide of the nutrient substance penetrating absorption principle, as well as promote the vitality of skin cells, 95% of which will efficiently absorb and reserve moisture and balance PH value to make the skin elastic and soft, and significantly improve low collagen synthesis which is related to aging. It can also efficiently prevent and reduce eyes' skin wrinkles and cutis laxa to restore the eyes' skin moist and elastic, and implement the nutrition lost because of the fluctuations in temperatures to promote the natural moisture ability of the skin around the eyes to make those skin instantly moisturized, smooth, refresh and outstanding radiant. The wrinkles and fine lines will be reduced at the same time, and the black circles will be no longer apparent.

本品采用天然的活性胶原蛋白多肽为原料,独有的SAYF融合弹性纤维的微纺技术,完美贴合眼部轮廓,可快速补充皮肤在外界所流失的水分,功效营养物质通过透皮吸收原理,快速渗透到皮肤的基底层,并渗提高皮肤细胞活力,其95%有效吸收留住水分,平衡PH值,使皮肤增加弹性和柔软性;明显改善与老化相关的胶原合成低下的现象,有效预防和减少眼部肌肤皱纹及松弛的现象,恢复润泽和弹性,同时补充眼部皮肤在各种温度不定的情况下流失的营养,提升眼周肌肤自然储水力,双眸瞬间滋润、光滑、丰盈,焕然一新,细纹与皱纹减少,黑眼圈变得不再明显。

Substantial collagenous fibril proliferation at the inner side and around the endoneurium was also observed.

电镜下,雪旺细胞出现在神经内膜管内,神经内膜管下及内膜管周围有大量胶原原纤维增生。

Methods The rat embryonic spinal cord astrocytes were cultured and identified by cellular morphology and glial fibrillary acidic protein.

体外原代培养大鼠脊髓星形胶质细胞并鉴定(胶质原纤维酸性蛋白GFAP阳性)。

Methods The active homograft bioprosthetic pediculated conduit preserved in liquid nitrogen were selected as experimental material and decellularized by sodium dodecyl sulplate containing low osmotic Tris buffer.

方法选取经液氮保存、具有活性的同种生物带瓣管道作为实验材料,用含十二烷基硫酸钠的Tris低渗缓冲液脱去同种带瓣管道存在的细胞;固定剂固定后,分别行HE染色、胶原纤维和弹力纤维染色的光镜和扫描电镜观察、摄片。

Fig 3Lots of rough endoplasmic reticula, mitochondrid an d collagen in the cytoplasm of fibroblast in control group

图3对照组的瘢痕成纤维细胞粗面内质网、线粒体丰富,形态结构正常,周围胶原纤维较多TEM×5200

Methods The changes of contents of AGEs in plasma and the abdominal aorta and changes of VSMC of the abdominal aorta were investigated with methods of fluorospectrophotometry, immunohistochemistry, computer image analysis and transmission electron microscopy on streptozotocin-induced diabetic rats. Results From the fourth week, in diabetic rats, the contents of AGEs in plasma and the abdominal aorta increased, the relative area of α-SM-actin in the abdominal aorta decreased, the density of nucleus of VSMC increased, and mitochondria and rough endoplasmic reticules in VSMC increased.

后者在早期主要是血管平滑肌细胞(vascular smooth muscle cell, VSMC)和胶原纤维增多,弹性纤维减少,动脉增厚等,引起动脉的顺应性降低,舒张功能减弱[1~3];晚期主要表现为动脉粥样硬化和动脉硬化,其中以VSMC的增生和迁移较为突出,其表型也由收缩型转化为合成型[4,5]。

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