纤维化的

Objective: To investigate the effects of matrine on the proliferation of rat cardiac fibroblasts induced by aldosterone , and to research the mechanism of regression of heart fibrosis.

目的：研究苦参碱对醛固酮诱导大鼠心肌成纤维细胞增殖的影响，探讨其抑制心肌纤维化的机制。

There are mainly two methods in the treatment of hepatic fibrosis. One is to aimdirectly at the causes by inhibiting hepatitis virus, killing blood fluke, alcoholwithdrawal, removing iron or coin, etc. The other is to suppress fibrosis itself byinhibiting the activation of HSC and proliferation of collogen, as well as promotingthe degradation of collogen.

抗纤维化的治疗一般包括两个方面：①是针对原发病的病因治疗，如抗肝炎病毒、抗血吸虫病、戒酒、去铁和去铜等；②是针对肝纤维化本身的治疗，如抑制HSC的激活、抑制胶原的增生、促进胶原的降解等。

Chitosan is a product of depolymerization and deacetylation of chitin, which has extensive biofunction because of its complex constructions.

目的：研究几丁糖对成纤维细胞增殖及Ⅲ型前胶原mRNA表达的影响，阐明其抗纤维化的作用机制。

Objective: To evaluate the therapeutic effects and mechanism of Huayulifei on blemycin-induced pulmonary interstitial fibrosis in rats.

目的：探讨化瘀理肺方对博莱霉素致大鼠肺间质纤维化的治疗作用及机制。

Objective To investigate the effects of piperazine ferulate on TGF-β1-induced renal interstitial fibroblast activation, and to explore the mechanism of PF in the prevention of renal tubulointerstitial fibrosis.

目的 观察阿魏酸哌嗪对转化生长因子－β1(TGF-β1)诱导肾成纤维细胞表型活化的影响，探讨其抗肾间质纤维化的可能机制。

The mRNA and protein level of bFGF was measured by semiquantitative reverse transcription polymerase chain reaction and immunohistochemical technique.

目的：检测碱性成纤维细胞生长因子在心房颤动患者心房组织中的基因表达，探讨其与心房纤维化的关系。

Objective To provide a proliferation model of human oral mucosal fibroblasts for the study of repair mechanism on oral submucous fibrosis.

目的为研究口腔黏膜下纤维化的修复机制，建立体外人口腔黏膜成纤维细胞增殖模型。

These results suggested that the lung Fib were activated and produced excess HA, resulting in the excessive accumulation of HA within the lung at the stage of alveolitis during the process of pulmonary fibrosis. However, increased HA synthesis of lung Fib and increased HA levels in BALF merely reflect the intensity of alveolitis and the disease activity rather than the degree of pulmonary fibrosis.

以上结果提示：肺Fib在肺纤维化的早期肺泡炎阶段就处于活化状态，产生HA增多，导致肺内HA的过多聚积，肺Fib产生HA增多和BALF中HA水平的增高可反映肺泡炎的强度和疾病的活动性，但并不能反映肺胶原代谢或纤维化的程度。

This pattern is characterized by the combination of pro-MMP-2 and membrane type 1 (MT1)-MMP expression, which drie pericellular generation of actie MMP-2 and local degradation of normal lier matrix. In addition there is a marked increase in expression of TIMP-1 leading to a more global inhibition of degradation of fibrillar lier collagens by interstitial collagenases (MMP-1/MMP-13). These pathways play a significant role in the progression of lier fibrosis.

其降解肝正常基质，同时抑制引起肝纤维化的纤维胶原降解，这种情况的特点是前明胶酶A合成和膜型1－MMP表达，使得小叶内细胞激活MMP-2和降解当处的正常肝基质，此外血浆1型组织基质金属蛋白酶抑制剂（TIMP-1）明显升高引起广泛的抑制间隙胶原酶(MMP-1/MMP-13)对纤维肝脏胶原的降解。

Following that the living environment was being deteriorated day and day and the living level was being continuously raised,fatty liver and symptom of fibred liver that menace the health of human beings gradually become the common diseases. These diseases have some complicated characteristics.

随着生活环境的日益恶化和生活水平的不断提高，脂肪肝和肝纤维化等症逐渐成为威胁人类健康的常见疾病，其病程长，不易治愈等特点，使得寻找预防和治疗脂肪肝及肝纤维化的有效药物，一直是国内外研究的热点。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。