纤维化的

Objective To investigate the effect of hepatocyte growth factor on expression of matrix metalloproteinase13, tissue inhibitors of metalloproteinase-1 and transforming growth factor β-1 in experimental hepatic fibrosis in rats and its possible mechanism.

目的 研究肝细胞生长因子对实验性肝纤维化大鼠的基质金属蛋白酶13(MMP-13)，抑制因子1(TIMP-1)，转移生长因子β1表达的影响，探讨HGF抗肝纤维化作用的可能机制。

In this dissertation, key technologies in ethanol production from lignocellulosic biomass including pretreatment, enzymatic hydrolysis of cellulose and hemicellulose, ethanol fermentation from hexose and pentose, and comprehensive utilization of lignocellulosic feedstock were investigated.

本文对木质纤维原料的预处理、纤维素和半纤维素的水解糖化、利用己糖、戊糖发酵乙醇、以及木质纤维原料的综合利用等关键技术进行了系统研究。

Pathologically, it showed palisaded granulomas containing degenerated collagen, predominantly lymphohistiocytic infiltration with scattered eosinophils leading to dermal fibrosis.

在病理下可发现有栅栏状排列的组织球围绕著变性的胶原纤维，而浸润的发炎细胞主要由淋巴球、组织球与散在性的嗜伊红球至后续的真皮层纤维化。

It is indicated that the direct kidney electrotransfer of hHGF gene was effective in preventing renal function injury and interstitial fibrosis of the transplanted kidney. It is relation of transfection of hHGF gene into the rat renal with reimplantation of the kidney suppressed tubulointerstitial injury and subsequent fibrosis in context of induced inchemia.

hHGF基因转染治疗对减轻移植肾的肾功能损伤和肾间质的纤维化具有远期效果，这种远期效果可能与hHGF基因对移植肾早期缺血再灌注损伤的保护作用及抗纤维化作用有关。

Objective:The aims of the present study were to determine the expression of transformation growth factor β 1 (TGF β 1) mRNA and TGF β 1 protein in the peripheral blood and its relation to serum levels of procollagen type Ⅲ N terminal peptide in the patients with cirrhosis.

转化生长因子-β1(TGF-β1)在一些体外和体内的研究中均显示能刺激胶原和细胞外基质的合成，同时又可通过抑制ECM降解以加强纤维的发生，在肝纤维化中起重要作用。

The alveolitis and pulmonary fibrosis were examined by HE staining. The serum HYP was examined .The expression of CTGF was tested by immunohistochemical assay.

HE染色检测肺组织肺泡炎及肺纤维化程度；测定血清羟脯氨酸的含量；免疫组化染色检测CTGF的表达。

Methods: 60 SD rats were divided into 4 groups randomly, the nomal group, the model group, QZHJ group, and the hydrocortisone group. Rats were sacrificed in bdtch on the 3rd, 7th and 21st day after treatment, then the concentration of interleukin-8(IL-8) in bronchoalveolar lavage fluid and the content of transforming growth factor-β1 (TGF-β1) of lung tissue were deected, while the severity of alveolitis and fibrosis were measured.

将60只健康SD大鼠随机分为正常组、模型组、芪术合剂组和强的松组，经气管滴入博莱霉素复制肺纤维化大鼠模型，并分组予以治疗，于治疗后第3、7、21日分批处死大鼠，每组每次6只；用免疫组化法观察肺组织转化生长因子-β1的表达，并测定支气管肺泡灌洗液中中性粒细胞和白介素－8的水平。

The results showed that ZBC can improve the rats mental state, diet, hair, increase their body weight,decrease remarkably ALT, AST, and GGT activity, raise ALB content and A/G, decrease the levelof serum HA, LN, PC III and IV-C, and decrease Hyp content of liver tissue, restrain mRNA expression of III collagen, relieve remarkably the inflammalion damage, fatly degeneration of the liver cells, and reduce the collagen fibre of the liver.

枳鳖胶囊可明显改善肝纤维化大鼠的精神状态、饮食、毛色泽，增加其体重；显著降低血清AST、ALT、GGT，显著升高血清ALB、A／G；降低血清HA、LN、PCⅢ、Ⅳ-C和肝组织Hyp含量；明显减轻大鼠肝细胞损害、肝脏脂肪变性和胶原纤维增生的程度；抑制Ⅲ型胶原mRNA的表达。

We hypothesized that MCP-1 may mediate fibrotic remodeling through recruitment of mononuclear cells and direct effects on fibroblasts.

我们假设MCP-1 可能通过单核细胞的复原和成纤维细胞的影响造成间接的纤维化重构。

The amphiphiles, 4-8, can not form reverse bilayers in organic solvent, which result in that the molecular interactions unable to meet the need for hydrophile-lypophile balance, so that they crystallize and exhibit no gelling abilities. The mono-chained L-alanine derivatives, 1-3, can self-assemble into bilayer aggregates, through intermolecular hydrogen bonding and homochiral effect in a number of organic liquids, which are juxtaposed and interlocked by van der Waals interaction, and finally gelate the organic liquids.

单链酰基化L-丙胺酸两亲物1-3在一些低极性的有机溶剂可以通过分子间氢键相互作用及同手性聚集作用形成有序的反双分子膜结构，这些有序反双分子膜结构单元依靠vander Waals力相互作用可以平行排列且相互之间进行连结形成长纤维状的聚集体，纤维状聚集体在有机介质中可以进一步相互连结形成三维网状结构，进而胶凝有机溶剂。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。