纤维化

2TGF-β1 and PDGF-B mRNA in liver tissue of liver-fibrotic rats can express increasedly, TGF-β1 and PDGF-B relate with the happening and developing of liver fibrosis closely.

肝纤维化大鼠肝组织TGF一p，和PDGF一B mRNA表达增加，TGF一pl和PDGF一B与肝纤维化的发生发展关系密切。

On experimental day （ day 0 ）, the rats were intratracheally instilled with bleomycin （ 5mg.kg -1 .body weight ）,and then treated with Angelica Sinensis 100mg.kg -1 and 200mg.kg -1 until they were killed.

按 BLM 5mg.kg -1 体重复制大鼠肺纤维化模型， 24 小时后给药，于 7 、 14 、 28 天观察肺间质纤维化形成的病理变化和肺匀浆中谷胱甘肽、透明质酸的含量变化。

Methods 30 patients with trichloroethylene medicamentous dermatitis and 30 normal persons were selected as the observation group and the control group respectively; color Doppler was used to detect the spleen thickness and longitudinal length, spleen vein and artery diameters, the maximum blood velocity and blood flow of spleen vein and artery; RIA was applied to determine the serum levels of HA, LN, PCⅢ, CⅣ and CG; relevant analysis was made on the linear relationship between serum indices of hepatic fibrosis and spleen hemodynamics of the two groups.

选择30例三氯乙烯药疹样皮炎患者作为观察组，30例同时期健康体检者作为对照组，用彩色多普勒超声仪，检测脾脏厚度及长径、脾动静脉直径、脾动静脉血流量和脾静脉最大流速SPV(下标 x。用放射免疫法检测肝纤维化指标透明质酸、层粘连蛋白、Ⅲ型前胶原、Ⅳ型胶原和甘胆酸的水平，并对观察组与对照组的脾血流动力学参数与肝纤维化指标进行相关分析。

Xiao Chai Hu Tang ;; Nitrosamines ;; Liver Cirrhosis, Experimental ;; Liver Fibrosis ;; Muridae ;; Swine ;; Serum ;; Fibrosis ;; Cells ;; Liver

小柴胡汤；；亚硝胺类；；肝硬化，实验性；；肝纤维化；；鼠科；；猪；；血清；；纤维化；；细胞；；肝

The mouse was carried out half nephric duct ligation to induce the renal interstitial fibrosis animal model,afterwards,to set up three groups,control group,sham operation group(intragastric administration with normal sodium according to 10ml/kg weight),treatment group...

采用小鼠单侧输尿管结扎法诱导肾间质纤维化的动物模型，用盐酸青藤碱治疗，并设对照组、假手术组(小鼠每日按10m l/kg体重用生理盐水灌胃，直至治疗结束)、治疗组(选用正清风痛宁缓释片按每日30mg/kg体重给小鼠灌胃，连续3周，)，检测血尿素氮、血肌酐、血清层粘连蛋白、纤维连接蛋白的含量，免疫组化法测肾脏组织转化因子β1(TNF-β1)的表达并进行肾脏病理学的观察。

Methods Routine and impulse oscillometry pulmonary function tests,including VC%,FVC% FEV1.0,FEV1.0/FVC%,PEF,FEF50,FEF25 and diffusing capacity of CO,were conducted in 35 normal subjects,38 patients with pulmonary fibrosis(Group 1) and 18 patients suffering from chronic obstructive pulmonary disease and pulmonary fibr...

方法单纯肺间质纤维化病人38例，慢性阻塞性肺疾病合并肺间质纤维化病人18例和健康人35例分别测定常规肺功能，包括肺活量、1秒量(FEV1.0)、1秒率(FEV1.0/FVC%)；呼气峰流速、50%用力呼气流速(FEF50)；25%用力呼气流速(FEF25)和一氧化碳弥散量。

The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells, especially near the hepatic centrolobular and periportal areas. Ovariectomy decreased ER level and ER mRNA expression significantly (P＜0.05). Hepatic ER and ER mRNA concentration were elevated after treatment with estrogen in both ovariectomy and sham ovariectomy fibrotic groups (P＜0.05), and the elevation of ER was correlated with a marked decrease in hepatic damage and fibrosis.

5肝脏ERα及其mRNA基因的表达分布于肝细胞及肝脏非实质细胞，特别以肝脏中央静脉和门脉周围为主；卵巢切除减少ERα及其mRNA基因的表达（P＜0.05）；雌二醇治疗在肝纤维化和卵巢切除大鼠均提高肝脏ER及其mRNA基因的表达（P＜0.05），其增加程度与肝脏组织学损伤、纤维化指标的降低程度以及肝脏胶原沉积减少相平行。

The rat im-munohepatic fibrosis model was made by intraperitoneal injection of porcine serum and treated with rhizoma sparganii and radices zedoariae. The ALT,GGT,TP, ALb, A/G, IVC,LN,HA and the pathological change of the liver were observed.

以腹腔注射猪血清制备大鼠肝纤维化模型，以ALT，GGT，TP，Alb，A/G比值，ⅣC，LN，HA及肝脏组织病理变化为指标，观察三棱、莪术对大鼠免疫性肝纤维化的影响。

The blood picture, bone marrow aspirates, marrow biopsy and reticulin fibrosis examination were performed before and after allo-BMT.

本文 1例 CML加速期合并明显骨髓纤维化患者，经 allo- BMT后，骨髓纤维化程度明显改善。

Objective To investigate the clinical characteristics of retroperitoneal fibrosis and explore the cause,diagnosis and treatment of it.

目的 加深对腹膜后纤维化的认识，探讨腹膜后纤维化的病因、诊断及治疗。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。