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纤维化

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ABSTRACT: Objective To investigate the protective effect of matrine and crataegus mixture on the renal interstitial fibrosis in unilateral ureteral obstruction rats.

目的 探讨中药复方苦参山楂合剂对肾间质纤维化大鼠结缔组织生长因子表达的影响以及其对肾间质纤维化的防治作用。

METHODS: Based on the comparison of serum fibrosis indices and alpha fetoprotein in 89 patients with viral hepatitis, their dynamic changes in different periods were studied dominatingly in 39 SH patients.

在比较89例病毒性肝炎患者血清肝纤维化指标及AFP水平的基础上,着重研究其中39例重型肝炎患者血清肝纤维化指标及AFP水平在不同时期的动态变化规律。

Then we discuss the equivariant fibration and several results about the ordinary fibration are generalized to the equivariant category.

此后,我们对等变纤维化进行了研究并将拓扑空间范畴中纤维化的一些结果推广到了等变拓扑空间范畴。

Objective To explore the role of expression of PTEN protein in fibrotic liver tissue during pathological process of hepatic fibrosis in rats.

目的 探讨大鼠纤维化肝组织中PTEN蛋白的定位分布及其在肝纤维化病理过程中的作用。

Objective To explore the relationship between hepatic vascular lesions and hepatic fibrotic and cirrhotic changes in chronic hepatitis.

在病毒性肝炎慢性化的过程中可出现纤维组织增生而导致肝纤维化和肝硬化。

Multiple genes are involved in the formation of hepatic fibrosis and there is a significant difference in gene expression between normal and fibrotic liver tissues.

多种基因参与肝纤维化的形成过程,肝纤维化组织与正常肝组织之间存在有明显的基因表达差异。

At end stage of fibrosis (28 day), a few weak immunostaining could be found in fibrotic lesions.

纤维化末期(28天)时,在纤维化灶内亦可见到少量分布的阳性反应区域。

Aim:To explore the clinical significance of serum fibrosis markers evaluated by histopathological findings.

目的:探讨肝纤维化血清标志物水平与病理纤维化分期的关系。

Blinded biopsies were evaluated by a histopathologist and scored according to Knodells histology activity index. Results 53.5%(54/101), 51.5%(52/101) and 31.7%(32/101) patients had a reduction of their total hepatic HAI score, necroinflammation and fibrosis scores by ≥2 points or 1 points at the end of one year of lamivudine therapy, compared with their pretreatment values, respectively.

结果 治疗后53.5%(54/101)患者肝组织学改善(治疗后HAI积分下降≥2),HAI积分由治疗前的8.0±4.7下降至治疗后5.2±3.3(t=7.358,P.01);其中51.5%(52/101)患者坏死炎症程度改善(治疗后积分下降≥2),坏死炎症积分由5.9±3.8下降至3.6±2.5;31.7%(32/101)患者纤维化程度改善(治疗后积分下降≥1),纤维化积分由2.1±1.2下降至1.6±1.2(t=3.827,P.01。

Results: Compared with sham controls, a progressive hyalinization and thicked wall of coronary arteries; perivascular fibrosis and interstitial fibrosis were observed in SAD rats.

结果:与Sham组相比,SAD大鼠心肌内冠状血管管壁呈进行性增厚、玻璃样变,管腔狭窄,血管周围纤维化和间质纤维化,心肌细胞肿胀、坏死和炎细胞浸润。

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