纤维化

Microscopically, extrahepatic biliary atresia leads to this appearance in the liver, with numerous brown-green bile plugs, bile duct proliferation, and extensive fibrosis.

显微镜下所示肝外胆管阻塞引起肝脏此种病变，有大量的棕绿色胆栓，小胆管增生、广泛的纤维化。

Microscopically, extrahepatic biliary atresia leads to this appearance in the liver, with numerous brown-green bile plugs, bile duct proliferation, and extensive fibrosis.

镜下见，肝外胆道闭锁导致肝脏大量黄绿色胆栓、假胆管增生、广泛纤维化。

Pathologic examination included: tubulointerstitial lesion which was the main pathologic presentation, tubular epithelial cell becoming flat, TEC necrosis and wither, departure between the cytoplasm and basis membrane, drops of protein in cytoplasm, broken basic membrane of TEC, inflammatory cells infiltrating in tubulointerstitium, tubulointerstitium fibrosis, plasm cell infiltration.

MM肾损害主要以小管-间质病变为主，病理表现为肾小管上皮细胞扁平，存在不同程度变性、坏死或萎缩，胞浆与基膜分离，胞浆内可见蛋白滴，甚至小管基膜断裂，间质炎性细胞浸润、纤维化，部分有淀粉样物质沉积，较少见浆细胞浸润。

This review focuses on the lately advanced progress on some important cytokines,including transforming growth factor-β,hepatocyte growth factor,immunoreactive fibronectin-γ,interleukin-10(IL-10),matrix metalloproteinases,tissue inhibitor of metalloproteinaseand augmentor of liver regeneration.

近年来肝纤维化的基因治疗选用的细胞因子主要包括转化生长因子β、肝细胞生长因子、γ-干扰素、白细胞介素-10(IL-10)、基质金属蛋白酶及其抑制剂等。

Methods Hepatic fibrosis models of rabbits were made by appling abdomen walls with the cercarias of Schistosome japonica.The rabbits were randomly categorized into four groups:normal control,4,8,12 weeks after application.The level of transforming growth factor-beta1(TGF-β1) mRNA in hepatic tissues was examined by reverse transcription polymerase chain reaction. The level of expressions of Smad3 was examined by Western blot. Meanwhile,immunohistochemistry staining was assessed by measuring type Ⅰ collagen .

日本血吸虫尾蚴腹贴法制备家兔肝纤维化模型(n =32 )，按诱导时间将动物随机分为 4、8、12周及正常对照共 4组，采用逆转录多聚酶链反应检测肝组织中转化生长因子TGF -β1mRNA表达水平，免疫组织化学法检测Ⅰ型胶原的表达，同时应用Westernblot检测Smad3蛋白的表达。

Objective Pseudomonas aeruginosais a Gramnegative bacterium that colonises the lower rspiratory tract in patients with bronchiectasis,cystic fibrosis and chronic obstructive pulmonary disease.

目的 铜绿假单胞菌(Pseudomonas aeruginosa，PA)是一种定植于支气管扩张、肺囊性纤维化和慢性阻塞性肺病病人下呼吸道的机会致病菌，可持续刺激宿主免疫反应导致进展性的气道破坏，具有多重耐药的特点，一旦感染，临床治疗十分困难。

pulmonary fibrosis;herbal medicine;prevention and treating;corticoid

肺间质纤维化；中药；预防和治疗；皮质类固醇

Key words pulmonary fibrosis;herbal medicine;prevention and treating;corticoid

肺间质纤维化；中药；预防和治疗；皮质类固醇

Results: Curcumine can effectively improve the biochemical and pathology grade.

结果：姜黄素对肝纤维化大鼠的肝胜病理分期具有明显的改善作用。

Objective: To investigate the effects of curcumine on the expresion of leptin and leptin receptor in rats with hepotic fibrosis.

目的：探讨姜黄素对实验性肝纤维化大鼠肝脏组织中瘦素以及瘦素受体表达的影响。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。