纤维化

Results: Expression of PAI1,TIMP1 and FN in kidney of diabetic rats began to increase in the second week of diabetes; PAI1 and TIMP1mainly expressed in intracytoplasm of renal tubular epithelial cells, while FN mainly expressed in renal tubule matrix and glomerului; Their expression showed a tendency of increasing along with the progression of diabetes.

本实验以糖尿病大鼠为动物模型，动态观察糖尿病2周、4周、8周、16周大鼠肾脏PAI1、TIMP1及FN表达的变化，从ECM代谢的角度探讨PAI1和TIMP1在糖尿病肾病肾纤维化发病机制中的作用。

Histologically, there were scanty lymphocytic infiltrate and marked fibrosis around hair follicles, especially the isthmus and infundibulum portion, without lichenoid inflammation its she papillary dermis.

组织学可见在毛囊周围，特别是上半部，有少量的淋巴球波浸润及明显的纤维化，而真皮乳突层内并没有大量苔癣样发炎的现象。

Objective: To evaluate the effects and possible mechanism of HMG-COA reductase inhibiter simvastatin on interstitial fibrosis of unilaterd ureteral obstruction rats and the influence of simvastatin on the process.

目的：本实验主要研究经甲基戊二酰辅酶A还原酶抑制剂辛伐他汀对单侧输尿管梗阻大鼠肾间质纤维化的影响及可能机制。

Methods 48 rats were randomly divided into saline control groups and silica instillation groups, and silicosis model was established in rats.

48只大白鼠随机分为二氧化硅灌注组和生理盐水对照组，制作大鼠硅肺纤维化模型。

The possible substrates of AF Begets AF in clinic are LAiD and blocking of the interatrial conduction et al.

慢性快速心房起搏房颤连缀模型犬有显著心房纤维化的病理改变和心房电重构。

Objective To explore the role of intercellular adhesion molecule-1 (ICAM-1) in experimental liver fibrosis.

目的 探讨细胞间黏附分子-1(ICAM-1)的表达及其在实验性肝纤维化发生中的作用。

In the reticular pattern there are too many lines, either as a result of thickening of the interlobular septa or as a result of fibrosis as in honeycombing.

在这个类型中，有很多线影。可能是小叶间隔增厚或是在蜂窝肺中的纤维化下面先上图，再解释。

The JHU researchers prospectively examined changes in fibrosis stage between paired liver biopsies in 67 coinfected patients. Of the 67 subjects, six were excluded due to cirrhosis on the first biopsy. The median age of group was 44 years, and 75% of the subjects were men. A total of 86% had CD4+ cell counts of less than 200 cells/mm3, and the same number of subjects were receiving antiretroviral therapy. Twenty-seven percent of the patients abused alcohol. The median time between biopsies was 2.84 years (interquartile range, 2.05 - 3.41 years).

JHU研究人员前瞻性地检验67位共同感染病患成对肝脏切片的纤维化严重度变化，在67位受试者中，6位因在第1次肝脏切片时就已经是肝硬化而被排除；受试者平均年龄为44岁，而且75%的受试者为男性；86%患者的CD4+细胞计数低於200 cellsmm3，而且同样数目的受试者接受抗反转录病毒药物治疗；27位病患有酗酒的习惯；切片之间的平均时间为2.84年（四分位数中距为2.05－3.41年）。

RAFE at all doses administrated interruptedly by gastric tube above 13 w caused chronic renal tubulo-interstitium fibrosis.The renal injury in functions and tissue forms in rats were similar with AA closely.The results showed that AA was the main toxic composition of RAFE.

RAFE小、中、大剂量灌胃给药13周以上可致大鼠慢性肾小管-间质纤维化，其肾功能和肾组织形态表现上与马兜铃总酸所致肾损伤相似，结果提示马兜铃酸是RAFE主要毒性成分。

In recent years, phenotypic changes of cells are found to be important in renal sclerosis and interstitial fibrosis.

近年来，研究发现细胞表型转化在肾硬化和间质纤维化过程中有重要作用。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。