纤维化

As long as the process is persistent and chronic, myocardial damage caused by any reason would induce MF of which results are refractoriness and arrhythmia in the end.

无论何种原因引起的心肌损害，只要病变持续和病程慢性化，终将导致心肌纤维化，其后果是难治性心衰和心律失常。

Influence of ganfujian granule on collagen sediment and hepatocyte proliferation were examined by Picric acid Sirus red staining and immunohistochemical staing methods, and analyzed by computer image analysis technique.

建立DEN诱导大鼠肝硬化模型，同时给予肝复健冲剂进行干预，应用天狼红-苦味酸特染法、免疫组化染色法及计算机图像分析技术检测中药对DEN致大鼠肝纤维化过程胶原沉淀及肝细胞增殖特性的影响。

The alveolitis and pulmonary fibrosis were examined by HE staining. The serum HYP was examined .The expression of CTGF was tested by immunohistochemical assay.

HE染色检测肺组织肺泡炎及肺纤维化程度；测定血清羟脯氨酸的含量；免疫组化染色检测CTGF的表达。

Methods: 60 SD rats were divided into 4 groups randomly, the nomal group, the model group, QZHJ group, and the hydrocortisone group. Rats were sacrificed in bdtch on the 3rd, 7th and 21st day after treatment, then the concentration of interleukin-8(IL-8) in bronchoalveolar lavage fluid and the content of transforming growth factor-β1 (TGF-β1) of lung tissue were deected, while the severity of alveolitis and fibrosis were measured.

将60只健康SD大鼠随机分为正常组、模型组、芪术合剂组和强的松组，经气管滴入博莱霉素复制肺纤维化大鼠模型，并分组予以治疗，于治疗后第3、7、21日分批处死大鼠，每组每次6只；用免疫组化法观察肺组织转化生长因子-β1的表达，并测定支气管肺泡灌洗液中中性粒细胞和白介素－8的水平。

The result showed that the experimental group can restrain thephosphorylation activity of P38MAPK and down-regulate the amount ofⅢtypecollagen hyaluronic acid and IL-6, improve the degree of alveolitis and pulmonaryfibrosis, decrease the expression of TGF-β1 in the lung tissue compared with themode group at all times.

研究结果显示：在各个时间点，肺痹汤各剂量组较模型组可以抑制P38MAPK磷酸化活性和下调Ⅲ型胶原透明质酸和IL-6细胞因子含量，改善肺泡炎及肺纤维化的程度，降低TGF-β_1在肺组织中的表达。

Jq Ez6_{0An outbreak of highly pathogenic avian influenza caused by H5N1 virus occurred in Vietnam, Japan and Korea, commencing in December, 2003. By February, 2004, it has been distributed widely in Asia and brought heavy losses. H5N1 are ball-like RNA viruses, birds can shed them via respiratory system, ocular secretions and feces, sometimes transferred to human and cause lethal infection. H5N1 patients have prominent features of reactive hemophagocytic syndrome,bronchiolar inflammation, necrosis of bronchial epithelium and organizing,diffuse alveolar damage with interstitial fibrosis.

2003年12月，H5N1型禽流感病毒在越南、日本和韩国爆发，到2004年2月，该病毒已在亚洲广泛蔓延并带来了巨大损失。H5N1是球型RNA病毒，禽类间可通过呼吸系统、眼分泌物和粪便传播，也可传染人类甚至导致死亡。H5N1感染者的特征是反应性噬血细胞综合征、细支气管炎症、支气管上皮坏死和机化、弥漫性肺泡病变和间质纤维化。

Extracellular matrix increased in the wall,resulting in collagenic and fiberous changes.

管壁细胞外基质增多，致管壁胶原化和纤维化。

Germ-line mutations in the genes hTERT and hTR, encoding telomerase reverse transcriptase and telomerase RNA, respectively, cause autosomal dominant dyskeratosis congenita, a rare hereditary disorder associated with premature death from aplastic anemia and pulmonary fibrosis.

分别编码端粒末端转移酶反转录酶和端粒酶RNA的hTERT和hTR基因的种系突变导致常染色体显性先天性角化不良，它是一种罕见的因为再生障碍性贫血和肺纤维化而早亡的遗传性疾病。

The Ganzhiping capsule composed of Jianghuang Chishao Haizao Fuling and compositon E has the efficiency of soothing the liver to regulate the flow of vital energy, strengthen the spleen by oozing wet firmly of invigorating blood circulation etc. It can effectively prevent and cure the fatty liver and acute liver-damage and chronic hepatitis cause to liver fibrination in clinic.

肝脂平胶囊是由姜黄、赤芍、海藻、茯苓和提取物E提取研制而成，具有疏肝理气、活血化瘀、软坚散结、健脾渗湿的功效，可有效的预防和治疗临床上的脂肪肝和急性肝损伤及慢性肝炎引起的肝纤维化等症。

The thickness of alveolar wall, the areas of mesenchyma in lung tissue were measured by HE staining. Immunohistochemical evaluation was to detect the expression of TNF-α, TGF-β1, FN protein.

灌药后第7、14、28天分组处死动物，提取肺组织，HE染色行肺泡炎、肺纤维化程度分级及免疫组化测定肺组织TNF-α、TGF-β_1、FN蛋白表达。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。