纤维化

With the higher levels of IL- 6 and IL - 8, it may promote chronicity of hepatitis and occurring on hepatocirrhosis, and worsened process of hepatitis.

IL-6和IL-8高水平的存在，可促进肝炎的慢性化和纤维化，加重肝炎的病程。

The liver fibrotic model was induced by CCl4 i.p for 5wk. Telmisartan was given at the same time model establishment in each intervened group by administration lasted for 6wk. Decollate to get the blood of all rats after 7 weeks . ALT、AST and ALB of serum was detected by automatic biochemistry equipment. Hyaluronic acid was detected by ELISA detection. Liver and spleen was obtained to calculate the index. The liver pathological changes were observed in each group of rats after HE staining to evaluate the therapeutic effect of Telmisartan; TGF-β1、PPAR-γand PDGF of liver tissue was detected by the method of immunohistochemistry respectively; The mRNA expression of TGF-β1、MMP-1、TIMP-1、α-SMA、PPAR-γand iNOS was detected by RT-PCR detection, respectively.

腹腔注射CCl4制备SD大鼠肝纤维化动物模型，连续灌胃6周，处死动物取血，检测血清ALT、AST、ALB；ELISA法测定血清透明质酸；取肝、睥，并计算肝、脾指数，组织切片HE染色后进行组织病理学疗效评估；用SP免疫组化法测定肝组织TGF-β1、PPAR-γ及PDGF蛋白表达；半定量RT-PCR方法检测肝组织TGF-β1、MMP-1、TIMP-1、α-SMA、PPAR-γ和iNOSmRNA的表达。

Results The allografts showed a typical symbol of acute rejection with excessive granulocyte infiltration around the vessel wall and myocardial interstice.

采用免疫组化半定量方法检测CTGF在心脏组织中的表达，并分析其与心肌纤维化的相关性。

Objective: To evaluate the therapeutic effects and mechanism of Huayulifei on blemycin-induced pulmonary interstitial fibrosis in rats.

目的：探讨化瘀理肺方对博莱霉素致大鼠肺间质纤维化的治疗作用及机制。

In this study, we observed the effect of mast cell tryptase on cultured human renal interstitial fibroblasts, so as to further investigate the effect of tryptase on renal fibrosis.

本实验研究肥大细胞类胰蛋白酶及蛋白水解酶抑制剂苯甲脒(benzamidine hydrochloride hydrate，BZ)对人肾成纤维细胞的影响，以探讨肥大细胞类胰蛋白酶在肾纤维化过程中的作用。

The annulus is richly innervated with painfibers, and further degeneratinon tends to be associated with more frequent and more intense episodes of pain.

无痛期间的特征是固定和僵凝，变性持续下去，纤维环和髓核的胶原结构发生变化并以纤维化及髓核碎裂告终。

RESULTS: The kwoninone has an could significantly inhibit fibro

苦参素可通过抑制成纤维细胞增殖及TGF-β1的表达而起到抗肝纤维化作用。

Over time, the fibers cause chronic inflammation, the development of pleural fibroses (a thickening of the pleural surfaces) and pleural effusions (buildup of fluid in the pleural spaces) and in many people, cancerous cell development.

随着时间的推移，这些纤维导致慢性炎症，使得胸膜纤维化和胸膜腔积液，并在大部分人中，癌细胞开始生长。

RESULTS: At 12 weeks after infusing thioacetamide, pathological section showed that hepatic lobules were destroyed; hepatic cord was disordered; liver cells had adipose degeneration, with few necrotic cells; interstitial fibrous tissues were hyperplastic, and folioles in some fibrous tissues, inflammatory cell infiltration were detected. These were the symptom of hepatic fibrosis.

结果：注射硫代乙酰胺12周时，病理切片显示肝小叶结构破坏，肝索排列紊乱，肝细胞脂肪变性，有少许坏死，间质纤维组织增生，有部分伸入小叶，有炎性细胞浸润，为肝纤维化症状。

Hepatic fibrosis ; hepatic stellate cell; platelet-derived growth factor; RNA interference ; glial fibrillary acidic protein ; gene therapy

国家自然科学；肝纤维化；肝星状细胞；血小板衍生生长因子； RNA干扰；胶质纤维酸性蛋白；基因治疗

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。