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纤维化

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Results:(1) CR 0%,PR 35.4%,MR 52.1%,effective rate 35.4%.(2) 40 cases show obvious focus fibrosis at 2nd stage operation.Postoperative pathological analysis conformed a widespread inflammatory cell infiltration and fibroplastic proliferation.

结果:①CR0%,PR35.4%,MR52.1%,有效率35.4%;②40例行2期手术,术中见病灶周围明显纤维化,术后病理证实病灶周围炎性细胞浸润和纤维组织增生。

We hypothesized that MCP-1 may mediate fibrotic remodeling through recruitment of mononuclear cells and direct effects on fibroblasts.

我们假设MCP-1 可能通过单核细胞的复原和成纤维细胞的影响造成间接的纤维化重构。

We hypothesized that MCP-1 may mediate fibrotic remodeling through recruitment of mononuclear cells and direct effects on fibroblasts.

我们由此推测MCP-1可能通过单核细胞的趋化作用以及直接作用于纤维母细胞来介导纤维化心肌重塑。

Objective: To explore the effect and happening mechanism of hdrochloric acid kukoline for the treatment of renal interstitial fibrosis,to supply some according for clinic how to resist glomeruli and nephric tubule interstitial fibrosis.

目的:探讨盐酸青藤碱在治疗肾间质性纤维化中的作用及其发生机制,为临床如何阻止、防止肾小球和肾小管间质纤维硬化提供借鉴。

Renal interstitial fibrosis ; LN ; FN ; Metaplasia factor ; Hdrochloric acid kukoline

肾间质性纤维化;层粘连蛋白;纤维连接蛋白;组织转化因子;盐酸青藤碱

Consistent findings in lung biopsies of AP patients included endothelialitis of pulmonary vessels, active fibrosis, lymphangitic inflammatory infiltrates rich in plasma cells and histiocytes with or without nodule formation, and fibrinous pleuritis.

这6例肺穿的其他共同特征包括肺血管内皮炎、纤维化、淋巴管炎细胞浸润(其内富于浆细胞和组织细胞,伴或不伴淋巴滤泡形成)、纤维素性胸膜炎。

Objective:To study the effect of spironolactone inhibiting proliferation on cultured myocardiac myofibroblasts and explore its possible mechanisms.

目的:研究螺内酯对培养的心肌成纤维细胞增殖的作用,揭示螺内酯抑制心肌纤维化的可能机制。

RESULTS: The extract of Aml could reduce the abnormally high levels of ALT and AST. Examined by light microscope , the degeneration and necrosis level of hepatocytes and the distribution of collagen fibrosis were markedly increased in the model group. The pathological changes and the c ollagen fibrosis associated with hepatic fibrosis decreased significantly in the prophylactically treated groups.

结果: 蓍草提取物预防给药能降低 CCl 4所致大鼠血清中异常增高的 ALT 、 AST 含量,光镜下观察肝纤维化模型组大鼠肝细胞严重变性、坏死,胶原纤维明显增加,蓍草预防各组大鼠肝细胞病理损伤得到明显改善。

Sixty six male Sprague-Dawley rats were randomly divided into control group,and 5 model hepatic fibrosis groups perfused alcoholic,maize oil and pyrazole for 2 weeks,4 weeks,8 weeks, 12 weeks and 16 weeks (11 rats in each group) respect...

结果 与对照组比较,酒精灌胃 4周、8周、12周、16周组大鼠OPN、α SMA表达显著增强并且肝内胶原纤维含量显著增加。正常肝组织中几乎不表达OPN ,在酒精性肝纤维化大鼠模型的建立过程中,从第四周开始中央静脉。。。

Key words] chronic Leukemia;myelofibrosis;reticulin fibre;m egakaryocyte.bone marrow biopsy

关键词]慢性白血病;骨髓纤维化;网硬蛋白纤维;巨核细胞;骨髓活组织检查

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