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纤维化

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Proliferation of fibroblastic cells in bone marrow,caus in g anemia and sometimes enlargement of the spleen and liver.

骨髓纤维化,骨髓纤维变性在骨髓中成纤维细胞的扩散,常引起贫血症,而且有时也会导致脾和肝的增大

ResultsMacroscopic examination showed no excrescence,thrombus formation,arm fractures and corrosion.The devices were covered with collagen fibrosis and discrete endocardial cells,apparent inflammatory infiltration in the devices and around the devices 1 month after implantation.The implants were nearly endothelialized,while the inflammatory reaction relieved gradually,with myocardial cells ingrowth at the edges of the device 3 months after implantation.The devices were completely covered with endocardium and fibrous tissue.Moreover,endothelial cells could be found on the smooth microscrew adaptor.The inflammatory reaction diminished with a few chronic inflammatory cells existing.Neovascularization and lymphatic vessels ingrowth could be observed 6 months after implantation.

结果所有封堵装置表面均没有发现赘生物、血栓形成、支架发生断裂及被腐蚀;术后1个月,封堵装置表面被胶原纤维和散在内皮细胞所覆盖,大量炎症细胞浸润,封堵装置边缘有小灶性炎症细胞浸润;术后3个月,封堵装置表面几乎被内皮细胞所覆盖,炎症细胞较1个月时明显减少,封堵装置内见纤维化,封堵装置边缘心肌细胞浸入;术后6个月,封堵装置表面完全被心内膜和纤维组织所覆盖,伞尖表面光滑并有内皮细胞上爬,炎症反应明显消散,但仍有少量慢性炎症细胞存在,装置内有新生的血管、淋巴管长入。

Objective To investigate the effects of Qing Gan Yin on collagen fibers and reticular fibers in hepatic fibrotic rats.

目的 研究中药清肝饮对大鼠肝纤维化模型胶原纤维和网状纤维的影响。

The positive expression rates of Tissue Inhibitors of Metalloproteinase-2 protein in the cases of involuting groups were significantly higher than those in proliferating group and vascular malformation groups and normal skin group (P.05). Its difference was significant. Conclusions: Matrix MetallProtinase-2 and Tissue Inhibitors of Metalloproteinase-2 may play an important role in the pathogenesis of hemangiomas through angiogenesis. They may have no effect on vascular malformation and normal skin

血管瘤退化期,TIMP-2表达明显升高,说明 TIMP-2与血管瘤纤维化、消退有关,其机制可能是一方面通过抑制MMP-2介导的基底膜降解而在内皮细胞迁移、聚集中起作用,另一方面直接抑制内皮细胞的增殖及迁移,使内皮细胞高频率调亡,细胞外基质增多,组织出现纤维化,最终导致血管瘤的退化。2、血管畸形和正常皮肤小血管中MMP-2和TIMP-2不表达或表达较弱,说明血管畸形和正常皮肤小血管中并不存在异常的血管生成,据此可以对血管性疾病进行分型、分期,并指导临床治疗。

After 6 months treatment, to observe the change of clinical symptoms, signs, hepatic function, hepatofibrosis index and B-ultrasonography. To estimate the curative effect caused by Ligan Kexian granule in terms of anti-hepatofibrosis.

观察治疗前后两组患者的症状、体征、肝功能、肝纤维化指标及B超影像学的变化,评价中药利肝克纤冲剂抗肝纤维化的疗效。

HSC may play an important role in the development and deterioration of liver fibrosis in diabetic tree shrews .

糖尿病树鼩早期肝纤维化中出现HSC激活现象,提示HSC激活在糖尿病早期肝纤维化的发生、发展中可能发挥重要作用。

To evaluate the quantitative acoustic densitometry technique in myocardial fibrosis diagnosis and to explore the effects of benazepril and valsartan on myocardial fibrosis.

目的探讨声学密度定量分析技术评估高血压心肌纤维化的价值,同时观察苯那普利和缬沙坦对高血压心肌纤维化的作用。

We focused on the expression and effect of TGF-β3 in the course of hepatic and pancreatic fibrosis, then investigated the effect of TGF-β3 on fibrosis

本文着重介绍了TGF-β3在肝脏及胰腺纤维化中的表达及其作用,以进一步了解其对纤维化疾病的影响。

Therefore, if you take this process one step further, you can hypothesise that for people in the very advanced stage of fibrosis, you might be able to reduce fibrosis in the advanced stage and make it return to a normal liver.

因此,如果进一步理解这个过程,可以假设,高纤维化程度的患者也能够减轻纤维化程度,并使它正常化。

Although LS closely correlates with fibrosis stage, it also increases in patients with inflammation which often confounds fibrosis in patients with ALD.

虽然肝脏硬度与纤维化阶段密切相关,但在炎症患者中亦有所增加。脂肪性肝炎常与酒精性肝病患者纤维化相混淆。

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