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It is characterized by ineffective erythropoiesis and by the presence of bi- and multinucleated erythroblasts in bone marrow, with nuclei of equal size and DNA content, suggesting a cytokinesis disturbance.

它的特征是无效红细胞生成以及骨髓中存在的双核和多核幼红细胞,这些细胞含有等量的细胞核和DNA成分,提示胞浆紊乱。

VCR (0.2 g/mL) and Fe3O4 nano-magnetic ferrofluid have no harmful effects to hematogenic immunologic function. Magnatic ferrofluid can even elevate the function of leucocytes. The results can supply experimental foundation for erythrocytes to capsulate both magnetic ferrofluid and anticancer drug, and also can provide treatment pathway for anticancer drug erythrocyte carrier targeting antitum or immunity.

VCR(0.2 g/mL)和纳米级 Fe3O4 磁流体对血细胞的免疫功能都没有不良影响,甚至磁流体还可以提高血液免疫反应中白细胞的免疫功能,为红细胞包载磁流体和抗癌药物治疗肿瘤提供实验依据,为抗癌药红细胞载体靶向抗肿瘤免疫提供新的治疗途径。

Erythrocytosis can arise from deregulation of the erythropoietin axis resulting from defects in the oxygen-sensing pathway.

缺氧信号传导途径的缺陷导致的红细胞生成素轴调控异常会引起红细胞增多症的发生。

Conclusion. The use of rhEPO effectively stimulated erythropoiesis in these patients and yet demonstrated no significant clinical benefit in reducing the likelihood of transfusion in neurogenic patients in this study.

本次研究中促红细胞生成素的使用显著刺激了患者的红细胞生成,但是在减少输血可能性方面并没有显著的临床获益。

Erythropoietin is a main growth factor that regulates the erythropoiesis under the physiological conditions and after blood loss.

红细胞生成素是机体在生理条件下以及失血后调控红细胞生成的主要生长刺激因子,是目前治疗由肾功能衰竭、慢性感染、获得性免疫缺陷综合征、肿瘤或其他原因引起的贫血病的特效临床药物之一。

Methods: This paper has collected 40323 normal reference values of Middle-aged Male's red blood cell count in 353 departments in China, using the method of microscope technique, and research the geographic distribution of normal reference value of Middle-aged Male's red blood cell count, the incliner 、complexity relationship characteristic between the normal reference value of Middle-aged Male's red blood cell count and geographic factors , including height above sea level , sunshine hours yearly , mean relative humidity yearly, mean temperature yearly , precipitation yearly, etc.

收集了中国353个单位用显微镜技术法测定的40323例中年男性红细胞计数正常参考值,运用BP神经网络和GIS空间分析,研究了其与海拔高度、年日照时数、年平均相对湿度、年平均气温、年降水量等地理因素间的非线性、复杂性关系特征及红细胞计数正常参考值的地理分布。

Methods Analyzed the clinical observation and nursing from 2004 to 2008 116 examples of monge disease patients,introduced the clinical manifestation,the prevention and the remedial measure with emphasis,as well as psychology and treatment and so on nursing.

回顾性分析2004年至2008年我院116例高原性红细胞增多症患者患病期间的临床观察和护理,重点介绍高原性红细胞增多症的临床表现、预防和治疗措施,以及心理及治疗等的护理。

The result indicated that ZXTMN group excelled the western medicine in the aspects of ameliorating symptom and hemodynamics, adjusting sugar and lipid metabolism, and reducing urine albumin and pltaelet adhesiveness and aggreagtion. The mechanism, which ZXTMN prescription could protect renal function, probably was (1) decreasing the level of sugar and glycosylated ferrohemoglobin;(2) decreasing AR activity of erythrocyte, improving SDH activity of erythrocyte, reducing accumulation of sorbitol in the erythrocyte, thus ameliorating the polyol metabolism;(3) accommodating lipid metabolism;(4) ameliorating coagulation, gathering, thick and mucosity of patient blood.

结果表明,止消通脉宁治疗组明显优于西药对照组,在改善症状,调整糖、脂代谢,减少尿白蛋白,改善血流变,降低血小板粘附和聚集等方面具有显著的疗效,分析其治疗早期DN的机制可能有以下几个方面:(1)降低血糖和糖化血红蛋白;(2)降低DN患者红细胞AR活性、提高SDH活性、减少红细胞内山梨醇积聚从而改善多元醇代谢;(3)调节脂质代谢;(4)改善DN患者血液凝、聚、浓、粘状态,抑制血小板的粘附聚集,从而改善肾脏微循环,保护肾功能。

vcr (0.2 g/ml) and fe3o4 nano-magnetic ferrofluid have no harmful effects to hematogenic immunologic function.

vcr(0.2 g/ml)和纳米级 fe3o4 磁流体对血细胞的免疫功能都没有不良影响,甚至磁流体还可以提高血液免疫反应中白细胞的免疫功能,为红细胞包载磁流体和抗癌药物治疗肿瘤提供实验依据,为抗癌药红细胞载体靶向抗肿瘤免疫提供新的治疗途径。

Results: Compared with the results of Group 1 frogility of erythrocy to membrane in infectious hepatitis,liver...

结果 :白细胞计数假性增高组病人中的黄疸型肝炎、肝硬化、肝癌患者的红细胞脆性均减小,而糖尿病患者红细胞脆性增加,且与正常对照组相比均有显著性差异(P 。0 5 )。

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