红细胞溶解

Experimental investigations have indicated that thrombin formation,red blood cell lysis,and iron toxicity play a major role in ICH-induced injury,furthermore,these mechanisms may provide new therapeutic targets.

实验调查表明，凝血酶生成、红细胞溶解和铁毒性在其中起主要作用，这些机制可能为临床提供新的治疗方向。

The self-made lysing solution can lyse red blood cells completely, but not destroy leukocytes and influence the expression of surface antigens on lymphocytes, monocytes and granulocytes significantly.

自制流式细胞仪专用溶血素具有很好的红细胞溶解效果，但不破坏白细胞，且对淋巴细胞、单核细胞和粒细胞群表面抗原的表达无明显影响作用。

Any substance that can cause lysis of erythrocytes and the release of their hemoglobin.

任何能引起红细胞溶解并释放血色素的物质。

MethodsNonheparinized autohemic blood of the rat was taken out from rat"s femoral artery and injected into its caudate nucleus immediately to establish a model of intracerebral hemorrhage.The changes of edema in the ipsilateral bassal ganglia , ipsilateral cortex, contralateral bassal ganglia and contralateral cortex were measured at 1,2,3,5 and 7 days respectively after intracerebral hemorrhage. The rat"s packed red blood cells, lysed red blood cells and hemoglobins at different concentrations were injected respectively into the rat"s caudate nucleus. The changes of edema in various regions of the brain at different time were measured as above. 5U thrombin was injected into the rat"s caudate nucleus and the changes of edema in various regions of the brain at different time were measured as above.

自体股动脉取血，并采用自体未肝素化新鲜血回注法建立大鼠尾状核出血模型，观察脑出血后1，2，3，5，7天血肿同侧基底节区、血肿同侧对应的皮质区、血肿对侧对应的基底节区及血肿对侧对应的皮质区脑组织水分含量的变化；分别以自体浓缩红细胞(PRBC，50％)、溶解红细胞(LRBC，50％)、不同浓度的大鼠血红蛋白注入大鼠尾状核，并观察不同时间不同部位脑组织水分含量的变化；以5U凝血酶注入大鼠尾状核，观察不同时间不同部位的脑组织水分含量的变化。

Multiple factors participated in the process of secondary brain edema and nerve injuries,such as the hydrostatic pressure during formation of the hematoma and clot retraction, activation of blood coagulation cascade, generation of thrombin,erythrocytolysis and the toxicity of hemoglobin, the activation of the complement system, space-occupying effects, rupture of the blood-brain barrier,secondary ischemia around the hematoma, inflammatory reaction of the neurons around hematoma and cell apoptosis.

脑出血后继发水肿及神经损害有多种因素参与，血肿形成过程中的流体静力压和血凝块的回缩、凝血瀑布的激活、凝血酶的产生、红细胞溶解和血红蛋白的毒性、补体的激活、占位效应、血脑屏障的破坏、血肿周围继发缺血、血肿周围组织神经细胞炎症反应及细胞凋亡等。

The results indicated that the erythropoietic/granulopoietic ratio was markedly increased with megaloblastic morphology in all stage of erythrocyte.

结果表明：2例CDAⅠ型患者骨髓幼红细胞比例增加，各阶段细胞存在不同程度巨幼样变；原红细胞核不规则，早幼或中幼红细胞可见奶酪核，约半数晚幼红细胞有核溶解和破碎现象，晚幼红细胞核损伤有时伴胞质溶解，细胞间染色质桥少见；各阶段红细胞核膜和内质网同时出现不同程度溶解。

They might not hemolyze spontaneously in the bottle, but they did not survive after transfusion.

红细胞可能没有自然地使溶解在瓶里，但红细胞在输血后不会生存。

The effect of erythrocytes on edema was mainly at the third day after intracerebral hemorrhage, as was probably relevant to the hemoglobin released by the lysed red blood cells. Its effect on edema formation was later than that of thrombin. These results provide a theoretical basis for therapeutic intervention.

红细胞对脑水肿形成的影响主要在脑出血后第3天，可能与红细胞溶解释放血红蛋白有关，由于其对脑水肿形成的影响在时间上比凝血酶要晚，从而在理论上能为治疗干预提供可行依据。

Hemolysis was evaluated in vitro through measuring erythrocyte lyses and ferrohemoglobin freeing degree with indirect contact method.

采用溶血试验检查材料对血液红细胞的溶解作用，测定红细胞溶解和血红蛋白游离的程度。

The selfmade lysing solution can lyse red blood cells completely ,but not destroy leukocytes and influence the expression of surface antigens on lymphocytes, monocytes and granulocytes significantly.

自制流式细胞仪专用溶血素具有很好的红细胞溶解效果，但不破坏白细胞，且对淋巴细胞、单核细胞和粒细胞群表面抗原的表达无明显影响作用。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。