红细胞发生

However, a form of anemia called pure red cell aplasia is a known risk of epoetins caused by the potential development of anti-erythropoietin antibodies.

但是，已知重组人促红细胞生成素可能通过生成抗促红细胞生成素抗体而导致一种称为纯红细胞再生障碍性贫血疾病的发生。

All patients presented at a young age with elevated serum Epo. Mutations at Gly-537 account for 4 of 5 HIF2A mutations associated with erythrocytosis.

所有病人在年轻时血清红细胞生成素较高，5个与红细胞增多症相关的HIF2A突变有4个是在Gly-537发生突变。

Erythrocytosis can arise from deregulation of the erythropoietin axis resulting from defects in the oxygen-sensing pathway.

缺氧信号传导途径的缺陷导致的红细胞生成素轴调控异常会引起红细胞增多症的发生。

ALAS2 expression is markedly increased during erythropoiesis to meet the demand for heme in hemoglobin production.

ALAS2基因的表达在红细胞发生过程中显著增加以满足血红蛋白合成增加时对更多血红素的需求。

From ultrastructure of RBC which co-cultured with HAP|,HAP4,HAP5,we have observed that HAPi and HAP4 can induce RBC membrane to deform and decrease stability of RBC membrane, so the particles can enter intramembrane, as a result, intracellular hydroxyapatite nanoparticles may heighten the concentration of Ca2+ and effect structure of membrane protein, membrane lipid and hemoglobin, subsequently,the deformability of RBC decreased all the better and leaded to erythrocyte aggregation. However,HAP.s uniformly dispersed around cell and didn't adhere to it,also, cytomorphosis cannot be found.

观察HAP_1，HAP_4，HAP_5与细胞作用后红细胞的超微结构中，HAP_1与HAP_4引起红细胞膜变形和膜稳定性下降，粒子进入胞内，进入胞内的HAP纳米粒子可能升高胞内Ca~(2+)浓度，从而影响膜蛋白、膜脂、血红蛋白的结构，使红细胞变形性进一步下降，最终导致聚集的发生。

An isoantigen that on exposure to its corresponding isoantibody causes agglutination of the red blood cells to which it is attached.

同种凝集原；同族凝集原一个同种抗原，在接触它相应的同种抗体的会导致与其附在一起的红细胞发生凝集

High copper also can cause the decrease of ATPase activity and membrane fluidity. These revealed that high dose copper destroied function of erythrocytic membrane and cause haematolysis, which may be one of mechanisms of the toxic effect induced by high dose copper.

高铜使红细胞渗透脆性增加，在酸性甘油溶液中的溶血速度(AGLT50)升高，细胞膜ATPase活性降低和膜流动性降低，表明高铜能够破坏红细胞膜的功能，进而使得红细胞发生溶破，这可能是高铜对羊红细胞毒性作用的机制之一。

Through the experiments on the serious exanimation alcoholism blood of fluorescence spectra of whole blood and erythrocyte induced by 407nm Xe lamp, it is shown that during the course when rabbits change from unconscious state to conscious state, the intensity of alcoholism blood of fluorescence spectra of whole blood and erythrocyte of the same concentration changes regularly.

研究了波长为407nm的非相干单色光激发严重酒精中毒的兔全血、红细胞混悬液，其荧光光谱的检测结果表明：随着酒精中毒出现昏迷到生物体征逐渐恢复的过程中，同一浓度的全血、红细胞溶液的荧光强度都发生了规律性的变化。

Objective To establish a Mycoplasm suis Kunming mouse model with blood from the Mycoplasm suis infected pigs to explore the laws, the occurrence and development and outcome, of this disease in rodents to reveal the pathogenic mechanism of Mycoplasma suis further.

目的 通过建立猪附红细胞体感染的小鼠模型，对附红细胞体在小鼠模型中的感染进行病理变化的检测，以探索该病在啮齿类动物体内的发生、发展及转归的规律，揭示附红细胞体的致病机理。

In the beginning, at the situation of high blood volume, if the blood glucose sufficient, the erythrocytic function of making ATP by glucose is normal, the free radical and the anti-free radical of the rat basicly keep balanced, erythrocytic deforming ability is not influenced greatly; while the erythrocytic function of making ATP degenerates in sport iron deficient erythrocyte formation and hemolysis, especially the former; and the vitalities of anti-free radical reduce greatly in blood, liver and Erythrocyte, the reducement of liver SOD vitality in the former and erythrocyte SOD vitality in the latter are more obvious, and the total blood SOD amounts reduce identically; The erythrocytic deforming ability reduces greatly too, but there is no obvious difference between the two groups, but the tendency of the inner-mechanism may be different needing to researching deeply later.

而长期递增的大负荷运动造成缺铁性红细胞生成或溶血发生时，红细胞利用葡萄糖制造ATP的功能下降，且前者下降更为明显；抗氧自由基活性均显著降低，HA组肝脏SOD活力和IDA组红细胞SOD活力降低更为明显，而二者血液总SOD降低一致；红细胞变形能力均显著下降，但内在机制的倾向性可能有所不同，建议进一步深入研究机理。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。