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红细胞减少

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Pure red cell aplasia is a rare and special type of aplastic anemia.

单纯性红细胞再障是一种罕见特殊类型的再障,血象及骨髓象中仅有红细胞减少而粒细胞及巨核细胞数正常。

Features of the related myeloproliferative disorder included isolated erythrocytosis, distinctive bone marrow morphology, and reduced serum erythropoietin levels.

相关骨髓增生碍的主要特征为:独立的红细胞增多,特征性的骨髓心态学以及血清中促红细胞生成素的减少。

Conclusion. The use of rhEPO effectively stimulated erythropoiesis in these patients and yet demonstrated no significant clinical benefit in reducing the likelihood of transfusion in neurogenic patients in this study.

本次研究中促红细胞生成素的使用显著刺激了患者的红细胞生成,但是在减少输血可能性方面并没有显著的临床获益。

It is with printing and section contrast, 124 smear have nuclear cell to decrease in, 58.9% decrease with the 66.1% positive that it is a holiday, common by accident for; of bring down of aplastic anemia, hematopoiesis printing and section cell quantity increase examine disease in, smear still has 26% decrease with the 36% negative that it is a holiday, common disease or conclusion are grow in quantity of red blood cell of lienal function hyperfunction, true sex disease, special the; such as disease of grow in quantity of the plaque that send a gender printing and section cell bring down person in, smear is accorded with rate (91.2% with 97.9%), and in the person that smear cell increases, printing and section are accorded with rate (95% with 100%) all tall.

以印片和切片为对照,124例涂片有核细胞减少中,58.9%和66.1%为假阳性减少,常见误诊疾病为再生障碍性贫血、造血减低;而印片和切片细胞量增加中,涂片仍有26%和36%为假阴性减少,常见疾病或结论为脾功能亢进、真性红细胞增多症、特发性血小板增多症等;印片和切片细胞减低者中,涂片符合率(91.2%和97.9%),以及涂片细胞增加者中,印片和切片符合率(95%和100%)均高。

The result indicated that ZXTMN group excelled the western medicine in the aspects of ameliorating symptom and hemodynamics, adjusting sugar and lipid metabolism, and reducing urine albumin and pltaelet adhesiveness and aggreagtion. The mechanism, which ZXTMN prescription could protect renal function, probably was (1) decreasing the level of sugar and glycosylated ferrohemoglobin;(2) decreasing AR activity of erythrocyte, improving SDH activity of erythrocyte, reducing accumulation of sorbitol in the erythrocyte, thus ameliorating the polyol metabolism;(3) accommodating lipid metabolism;(4) ameliorating coagulation, gathering, thick and mucosity of patient blood.

结果表明,止消通脉宁治疗组明显优于西药对照组,在改善症状,调整糖、脂代谢,减少尿白蛋白,改善血流变,降低血小板粘附和聚集等方面具有显著的疗效,分析其治疗早期DN的机制可能有以下几个方面:(1)降低血糖和糖化血红蛋白;(2)降低DN患者红细胞AR活性、提高SDH活性、减少红细胞内山梨醇积聚从而改善多元醇代谢;(3)调节脂质代谢;(4)改善DN患者血液凝、聚、浓、粘状态,抑制血小板的粘附聚集,从而改善肾脏微循环,保护肾功能。

The pre erythrocytic stage vaccines aim to prevent the development of all clinical symptoms and subsequent malaria transmission. Erythrocytic stage vaccine designed aims to induce antibodies that prevent invasion and infection of erythrocytes, to reduce morbidity and mortality by decreasing the parasite load.

作用于红细胞前期的疟疾疫苗主要是抑制疟疾的临床发作,控制疟疾的传播;作用于红细胞期的疟疾疫苗诱导宿主体液免疫系统,产生特异性抗体,抑制疟原虫侵入和感染红细胞,达到减少疟原虫虫荷,降低疟疾的发病率和死亡率。

On closer scrutiny of the presenting blood count, despite normal haemoglobin and packed-cell volume,there was microcytosis with reduced mean corpuscular volume(74.5fL;NR 80-96fL)and hypochromia(mean corpuscular haemoglobin 23pg;NR 27-32pg).

对现有血细胞计数的详细分析,我们发现虽然有正常的红细胞计数和红细胞压积,但是存在平均血细胞体积减少(74.5fL;正常值范围 80-96fL)和血红蛋白减少(平均血红蛋白含量23pg;正常值范围 27-32pg

Results Erythrocyte count, hemoglobin concentration and hematocrit of all the patients with malignant digestive tumor decreased, mean corpuscular volume and mean corpuscular hemoglobin increased, arid there was inconspicuous change in total leukocyte count. The indications of megaloblastic anemia and proliferative anemia in bone marrow hemogram were found in the patients. It was common that the percentage of neutrophils was higher and that of lymphocytes was lower than that of the normal controls.

结果 消化道恶性肿瘤患者的红细胞计数、血红蛋白、红细胞压积均减少,平均红细胞体积、平均红细胞血红蛋白量增高,均表现为巨幼细胞性贫血,骨髓象呈增生性贫血改变,而白细胞总数的变化较小,白细胞分类,中性粒细胞百分比超过正常范围与淋巴细胞百分比低于正常范围者多见,血小板数异常远较血红蛋白与白细胞为少,但36例肝癌患者中28例出现血小板减少。

Beta-thalassemia major is a serious hereditary hemolytic anemia which does great harm to human being.It is a monogenic disease characterised by a reduced synthesis of beta-globin chains,which dues to the Doint mutation or deletion of beta-globin gene and its control region.It not only decreases the hemoglobin level,but breaks the balance of alpha/beta synthesis ratio.The major cellular pathogenetic mechanisms in beta thalassemia are based primarily on the deleterious effects produced by the accumulation of the excess alpha globin chain.These excess alpha-globin chains cannot form stable tetrameric structure and deposit in erythroid cells.They cause large ineffective erythropoiesis on their own,accelerate red cells destruction,and lead to hemolysis.

地中海贫血是一种对人类健康危害严重的遗传性溶血性贫血病,是因β-珠蛋白基因及其调控序列的点突变或缺失致使β-珠蛋白肽链合成减少或完全停止,这不仅使患者血红蛋白水平降低,而且使原来在数量上与之持平的α-珠蛋白肽链相对过剩,这些相对过剩的游离α-珠蛋白肽链并不能形成稳定的四聚体,它们沉积在红细胞中导致了大量无效红细胞生成和红细胞寿命缩短,引起了严重的溶血性贫血。

When ethanol goes into the red blood cells, osmotic pressure changing causes the cell vertices moving to the center, and double-concave disc surface will be the spherical one. It results in the red blood cell volume larger and surface area smaller, causes the ratio of the surface area and volume significantly decrease, and the resistance tensile capacity of red blood cells reduced.

分析认为乙醇进入红细胞后,由于渗透压的变化将使细胞顶点向中心移动,双凹形的圆盘曲面将向球形细胞转变,导致红细胞体积变大和表面积的减少,引起红细胞表面积和容积的比值显著变小,红细胞的抗张能力降低。

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