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红斑狼疮

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Results Among 4913 TRUST tests,57 occur the biological false positive reactions,the most occur the lepra,about 31.82% of the lepra patients,secondly RA 17.78%;systemic LE 17.02%,hepatitis 5.43%,scleroderma 3.33%,dermatomyositis 3.13%,activity tuberculosis 1.82%.

结果 4913例TRUST试验,57例发生生物学假阳性反应,麻风发生率最高,占麻风病例的31.82%,依次为类风湿关节炎17.78%,系统性红斑狼疮17.02%,变应性血管炎6.67%,乙型肝炎5.43%,硬皮病3.33%,皮肌炎3.13%,活动性肺结核1.82%,孕妇0.68%,正常人0.08%。

Results Among 4913 TRUST tests,57 occur the biological false positive reactions,the most occur the lepra,about 31.82% of the lepra patients,secondly RA 17.78%;systemic LE 17.02%,hepatitis 5.43%,scleroderma 3.33%,dermatomyositis 3.13%,activity tuberculosis 1.82%.

结果 4913例TRUST试验,57例发生生物学假阳性反应,麻风发生率最高,占麻风病例的31.82%,依次类风湿关节炎17.78%,系统性红斑狼疮17.02%,变应性血管炎6.67%,乙型肝炎5.43%,硬皮病3.33%,皮肌炎3.13%,活动性肺结核1.82%,孕妇0.68%,正常人0.08%。

In order to investigate the relationship between systemic lupuserythematosus and the complicated infection, we analysed 109 cases of SLE inpatients with complicated infection.

为探讨系统性红斑狼疮与各种病原体感染的关系,对109例SLE住院病人合并感染情况进行了分析。

Objective:To study the hematology abnormality in systemic lupuserythematosus and progressive systemic sclerosis.

目的:研究系统性红斑狼疮及系统性硬化症的血液学异常情况,进一步指导诊断及鉴别诊断。

Inspection of the oral mucosa may faciltate diagnosis of such diseases as pharyngitis, tonsillitis, mucositis, oral candidiasis or oral ulcerations, each of which may present clues to such diseases as SLE, HIV infection, herpes simplex, leukemia, megaloblastic anemia, or Behcet's disease.

检查口腔粘膜有助于咽炎、扁桃体炎、粘膜炎、口腔白色念珠菌病或是口腔溃疡的诊断,从而为系统性红斑狼疮、艾滋病、单纯疱疹、白血病、恶性贫血或 Behcet 病等疾病提供线索。

In this review data on the use of rituximab is presented from 92 studies involving 1197 patients with the following diseases: systemic lupus erythematosus, idiopathic thrombocytopenic purpura, anti-neutrophil cytoplasmic antibody associated vasculitis, Grave's disease, autoimmune hemolytic anemia, pemphigus vulgaris, hemophilia A, cold agglutinin disease, Sjogren's syndrome, graft vs. host disease, thrombotic thrombocytopenic purpura, cryoglobulinemia, IgM mediated neuropathy, multiple sclerosis, neuromyelitis optica, idiopathic membranous nephropathy, dermatomyositis, and opsoclonus myoclonus.

本综述资料总结了92项共1197例患者应用利妥昔的研究,包括系统性红斑狼疮、特发性血栓性血小板减少性紫癜,抗中性粒细胞抗体相关性血管炎、甲状腺功能亢进、自身免疫性溶血性贫血、寻常型天疱疮、甲型血友病、冷凝集素病、干燥综合征、移植抗宿主疾病、血栓性血小板减少性紫癜、IgM介导性神经病、多发性硬化、视神经脊髓炎、特发性膜性肾病、皮肌炎和眼肌阵挛性肌阵挛。

CD40/CD40L interactions were also shown to play a significant role in the maintenance of autoimmunity,High-level expression of CD40L and CD40have been detected on monocytes/macrophages from patients with active sgstemic lupus erythematosus,rheumatoid arthritis and other autoimmune diseases,indicating that the expression of CD40/CD40L on monocytes/macrophages could account for the formation of synovitis and osteoclasia.

CD40/CD40L是免疫细胞间的重要信号转导途径,单核巨噬细胞表达CD40与CD40L,分泌许多促炎性因子,参与类风湿关节炎滑膜炎形成、骨和软骨破坏。在系统性红斑狼疮、类风湿关节炎和其他自身免疫病中已检测出高水平表达的CD40与CD40L。

Objective To investigate the clinical features of osteonecrosis of the femoral headin patients with systemic lupus erythematosus.

摘 要:目的探讨系统性红斑狼疮并发无菌性股骨头坏死的临床特点。

On the other hand, most patients with papulosquamous subtype of SCLE developed systemic LE manifestions.

目的探讨两型亚急性皮肤型红斑狼疮患者病情演变的差异。

Two patients with generalized herpes zoster complicated with tumor and 3 patients with dermatomyositis, bullous pemphigoid and systemic lupus erythmatosus respectively, who did not respond to routine treatments were treated successfully by high-dose intravenous gammaglobulin.

采用大剂量静注丙球冲击疗法治疗2例伴发肿瘤的泛发性带状疱疹患者,常规治疗效果欠佳的皮肌炎、大疱性类天疱疮和系统性红斑狼疮患者各1例,剂量为0.4/共5天,并辅以中等剂量的皮质类固醇激素。

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