紫癜的

Fluorescein isothiocyanate labeled polyclonal goat antihuman immunoglobulin antibody was added, and flow cytometer was used to detect bead-platelet-associated autoantibodies-antihuman immunoglobulin antibody complex. Results The fluorescene ratio of four monoclonal antibodies was significantly different (P .01) between the idiopathic thrombocytopenic purpura patients and either the non-ITP patients or the normal controls. If the upper limit of normal control was set as cutoff value, ratios of greater than 1.37, 1.24, 1.48, and 1.19 were considered positive for the four monoclonal antibodies respectively. The flow cytometric bead assay had an overall sensitivity of 73.17% and a specificity of 94.29%.

结果 特发性血小板减少性紫癜组4种单抗荧光强度比值与非ITP血小板减少组和正常对照组有显著性差异（P＜0.01）；若将ITP组患者4种单抗荧光强度比值分别大于正常对照组上限1.37、1.24、1.48和1.19判断为阳性，则流式微球技术检测血小板特异性自身抗体的敏感性为73.17%，特异性为94.3%；4种单抗联合检测总体敏感性明显高于改良间接单抗特异的血小板抗原固定试验（P＜0.05，且大于各单个抗体检测敏感性。

Objective The study of relationship among idiopathic thrombocytopenic purpura,virus infection and platelet-associated autoantibody in different age children.

目的 探讨不同年龄组的儿童特发性血小板减少性紫癜与病毒感染及血小板相关抗体的关系。

Purpura, angioedema, and facial swelling were not seen, but dermographism was present in 1 patient. Six patients had fever, 7 had polyarthritis, and 6 had leukocytosis. Seven patients had associated systemic diseases: adult-onset Still disease (3 patients), systemic lupus erythematosus (3 patients), and Schnitzler syndrome (1 patient).

没观察到紫癜，血管性水肿和额面水肿，但是有1名患者有皮肤划痕现象，6名患者有发热，7名有多发性关节炎，还有6名有患者有白细胞的增多。7名患者与全身性疾病有关：成人发病的斯蒂尔病（3名），全身性系统性红斑狼疮（3名）和薛尼兹勒氏综合症（1名）。

Methods: iEstablishing the animal model of HSP :Gliadin being taken as food antigen,meanwhile reticuloendothelial system being blocked by India ink,these two methods were applied to make mouse under the condition of clearance deficiency in reticuloendthelial system...

1。建立过敏性紫癜实验动物模型：以麦胶蛋白作为饮食抗原，加用印度墨水封闭网状内皮系统的动物造模方法，使模型小鼠在网状内皮系统清除功能缺陷的前提下，持续抗原刺激粘膜免疫系统，建立HSP实验动物模型。

It is important to differentiate immune thrombocytopenia from nonimmune thrombocytopenia because of the different clinical treatment, but untill now there is no satisfactory laboratory tests could be used.

非免疫性血小板减少性紫癜，是指由非免疫因素引起的血小板减少，如化疗后骨髓抑制、急性白血病、脾功能亢进以及恶性肿瘤骨髓转移等引起的血小板减少。

The expression of CD11b was measured by flow cytometry in 12 patients and normal controls, and plasma levels of elastase by ELISA in 20 patients and normal controls.

采用ELISA法检测20例过敏性紫癜患者活动期及缓解期血浆弹性蛋白酶水平的变化，并与20例正常人进行比较。

Recent studies suggest that ITP is related to the abnormal activation and apoptosis of T/B cells which lead to failure of immune tolerance.

特发性血小板减少性紫癜是以血小板在网状内皮系统中被巨噬细胞过度破坏为特征的自身免疫性疾病。

In spleens from HIV-infected patients with thrombocytopenic purpura, these characteristics were unaffected.

HIV感染合并血小板减少性紫癜患者的脾脏中，这些特征不受影响。

Result: The observation group have less time for disappearing of symptoms such as purpura,bellyache, arthralgia and urinary protein than those in the other group(P.01).And the recured rate was obviousby lower in obsewation grap.

结果：观察患儿皮肤紫癜、腹痛、关节痛及尿蛋白消失时间和住院时间明显低于对照组(均P.01)；观察组的复发率明显低于对照组(P.01)。

Methods:The 62 patients with HSP from 1999 to 2002 were randomly divided into the heparin calcium treatment group (32 cases) and the non-heparin calcium treatment group (30 cases). At the same time, 25 cases of non-HSP belonged to the normal control group. Alb, 13 2-MG and IgG of urine were monitored constantly.

将62例过敏性紫癜患儿随机分成肝素钙治疗组(32例)和对照治疗组(30例)，另设非HSP对照组25例，追踪监测尿微量白蛋白，尿β2-微球蛋白(β2-MG)，尿免疫球蛋白G，从而判断肾损害的情况。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。