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With the development of the China's national economy, especially after China's having joined the WTO, the districts anear oceans are facing increasingly fierce market competition as a link used for connecting the outside word. Therefore the strategic theories have been paid more attention on the development of the districts anear oceans.

内容摘要:随着我国国民经济的发展,特别是中国加入 WTO 以后,临海地区作为一个与外界紧密连接的窗口和物字流动的纽带,面临着日益激烈的市场竞争,用战略的理论来规划临海地区的发展越来越引起人们的重视。

In this way Apollinaris established so close a connection of the Logos with human flesh, that all the divine attributes were transferred to the human nature, and all the human attributes to the divine, and the two merged in one nature in Christ.

这样,亚坡理纳建立紧密连接的标识与人的肉体,一切神圣的属性被转移到人的本质,和所有人类的属性,以神圣的,而且两国合并在一个自然在基督里。

There were rope- ladder-like patterns capillary nets around seminiferous tubules in postnatal 3 and 12 months.

2l'少}抖1」龄fl1可见支持细胞间不典型的紧密连接,24月龄纸未见到紧密连接。

But at least their research objects are highly crossed and deeply storied, closely connected as a triangular combination.

至少它们的研究对象是高度交叉的、深度分层的,或分区段紧密连接的一种类似三角形的综合体。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果:1、哇巴因作用于晶状体钠泵后,光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙,电镜下全层细胞空泡化、线粒体肿胀出现髓样结构,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后,光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离,电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后,光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整,电镜下细胞器丰富、细胞功能旺盛,RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后,光镜下晶状体质膜完整、细胞排列紧密规整,电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝,RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后,光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化,电镜下囊侧膜内有高电子密度带、细胞核仁丰富,RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后,光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏,电镜下质膜变性、线粒体肿胀,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

Results The electron microscopical observation demonstrated that intracellular lanthanum could be found,most of which entered the hepatocytes and its mitochondria. The lanthanum granules were also found to deposite in the zone of tight junctions of bile canaliculi, indicating that the tight junctions had been damaged.

结果 镧示踪标记法显示镧颗粒进入了细胞及线粒体内;毛细胆管紧密连接区也出现了致密的镧沉积,并与肝细胞间隙的镧沉积物相连,表明毛细胆管紧密连接已开放。

Our aim was to study the morphological changes of tight junctions in allografts during rejection.

我们的目标在于研究排斥发生期间移植物小肠紧密连接的形态学改变。

Objective: To investigate the effects of high glucose peritoneal dialysis solution and "Astragalus Injection" combined with peritoneal dialysis solution on tight junction of peritoneal mesothelial cells and the expression of zonula occluden-1(ZO-1) in rats.

目的:观察高糖腹膜透析液和添加不同剂量黄芪注射液的腹膜透析液对腹膜间皮细胞紧密连接形态结构和紧密连接相关蛋白封闭蛋白-1(ZO-1)表达的影响。

Blood-brain barrier in tumors and peritumoral oedematous regions had the same variations in ultrastructure.

瘤体和瘤周水肿区血脑屏障超微结构变化无明显差异,内皮肿胀,毛细血管腔狭小,胶面有稀疏的绒毛样突起,内皮为无孔型,胞质内胞饮泡较多,内皮紧密连接增长,细胞连接间隙增宽,基膜完整,胶质膜缺损。

Objective To investigate the role of the ultrastructure alteration of tight junction between capillary endothelial cells in pulmonary fibrosis.

目的探讨血管内皮细胞间紧密连接的改变在肺纤维化发生发展过程中的作用。

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