素因子

The recognition mechanisms of GGR and TCR to UVB-induced photodamages were summarized: Xeroderma Pigmentosum group C, the recognition factor in GGR, executed its function avoiding direct contacting with lesions; the conversion between monomer and dimer of Cockayne syndrome B protein was underlined in the recognition of TCR; ubiquitylation mediated by DNA damage binding protein played an important role in NER recognization at chromatin level; moreover, the fate of the recognition factors was also discussed.

识别因子XPC通过一种不直接识别损伤本身的机制在GGR识别过程中发挥作用；在TCR识别过程中强调了关键因子CSB单体及二聚体两种形式的转换。在染色质水平上，DDB介导的泛素化作用是NER识别过程中重要的调控要素。另外，完成使命的识别因子的最终走向也是NER途径中的一个重要环节。通过分析上述生化过程，较清楚地总结了GGR及TCR对UVB导致的光损伤的识别机制。

The main work and innovation1 In general , a image compression method has different effect to different image . Some are fit for image which has much high frequency . Some are fit for image which has much low frequency .This paper analysis the applicability of fractal algorithm . In this dissertation , an improved algorithum is given . The basic algorithum without eight change and the joint use of quantitative coding , The compression ratio and PSNR can be adjusted , and it can get more quickly speed of coding .2 To a group of exact fractal code , the decoding image can be any resolution .With this characteristic ,choose the proper domain block and range block,this paper get an algorithum which can get higher decoding PSNR and speed than the basic fractal algorithum.3 Give a new method to calculate the scale factor . The calculation of basic algorithum is complex and enormous . The factor of scale is an important variable of the basic algorithm. Now there are two methods to calculate the factor of scale .A new method was given to calculate the factor of scale. The calculation load and complexity are reduced by the new method. Compared with the basic algorithm , the method can reduce coding time.4 The basic fractal algorithum is based on the Collage theorem and contraction mapping theorem . A mathematic model based on basic fractal algorithum is given .

本文的主要工作及创新点主要包括以下几点：1一般情况下，一种图像压缩的方法对不同特点的图像，压缩效果会有所不同，本文利用分形压缩编码对不同特点的图像进行编码，分析了分形编码对不同图像的编码适用性，利用去掉8种变换的分形编码算法与简单的均匀量化编码方案相结合，得到了一种可以调节压缩比与解码质量的分形编码方案，该提高编码速度6倍以上。2分形编码的特点之一是分形解码的分辨率无关性，即对于一组分形编码可以将其解码到任意分辨率下，本文利用分形编码的这一特点，结合不同的量化编码方案，选择合适的定义域块与值域块及适当的编解码分辨率，得到了一种提高解码质量，编码速度提高12倍以上的加速算法。3比例因子是基本分形算法中的一个重要变量，目前有两种计算比例因子的方法，文中给出了一种新的求比例因子的方法，该方法简化了求比例因子的计算，从整体上减小了基本分形算法的计算量，简化了算法4分形压缩的数学基础是不动点定理与拼贴定理，本文根据基本的自动分形编码方法，建立数学模型对其进行推导，得到了用普通数学的极限理论解释分形编码的数学表达式，从而对由基本分形编码得到的解码图像中的像素点的值给出了确定的表达式。

There is also in the skin lesions of psoriasis immune globulin, complement, anti-IsA factor, anti-keratin antibodies and parakeratotic nuclei antibody, etc., these factors result in abnormal T lymphocytes in the immune cycle of separatist injury and the number of T lymphocytes in significantly reduced, such as the Con A stimulus-response is reduced, while phytohemagglutinin and pokeweed mitogen factor is a normal reaction, this phenomenon is to support T-cell subsets flawed.

在牛皮癣的皮损中还有免疫球蛋白、补体、抗IsA因子、抗角蛋白抗体及角化不全细胞核中有抗体等，这些免疫异常因子造成T淋巴细胞的周期分裂性损伤和T淋巴细胞数量明显减少，如对刀豆球蛋白的刺激反应性下降，而对植物血凝素和商陆有丝分裂因子却反应正常，这种现象支持T细胞亚群存在缺陷。

Many literatures focus on preterm prediction study and evaluate every predictor. The predictors include cervical length and the size of some of fetal organs measured by ultrasound; the level of fFN, IGFBP-1, IL investigated in cervicovaginal fluid, serum relaxin, CRP and HbA1c in mother's blood, MMP-8, MCP-1 and ITAC in amniotic fluid which correlated with infection.

早产的预测是研究热点，大量文献分别从超声测量学角度，包括宫颈长度，胎儿某内脏的测量；宫颈阴道分泌物中多项指标，如胎儿纤维结合蛋白、磷酸化及脱磷酸化胰岛素样生长因子连接蛋白-1、白细胞介素的测定；血生化分析，如血清松弛肽、C反应蛋白、糖化血红蛋白含量的变化及羊水化验与感染有关的一些因子，如快速基质金属蛋白酶8、单核细胞趋化蛋白-1、γ干扰素诱导T细胞α趋化因子等，阐述各指标对早产的预测价值。

Affect of kwoninone on fibroblastic proliferation, morphology and expression of TGF-β1

论文天下提供的免费论文，内容包括苦参苦参素纤维细胞增殖细胞增殖形态学因子生长因子β1 转化生长因子

The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser CTCF, and kruppel-like zinc finger protein; two members of the ADAMs (a disintegrin and metalloprotease domain) family; two members of integrin family; several proteins involved in the signal transduction, cell-cycle control, chromatin remodeling and transcription repression; and also some proteins of cell skeleton and some with unknown functions.

鉴定出 的蛋白包括多个与转录调控相关的锌指蛋白，如锌指蛋白198、263、14、224、zf6、转录抑制因子cTcF样蛋白、幻肚pple样锌指蛋白等：两个含金属蛋白酶结构域和整合素结合结构域的家族成员ADAM28和ADAM17；两个整合素家族成员pZ整合素和含十个EGF样结构域的整合素；与细胞信号转导通路有关的蛋白；与细胞周期调控有关的蛋白；与染色体重塑和基因转录抑制有关的蛋白；细胞骨架蛋白以及其他功能未明的蛋白等。

Interleuk in 2 (IL-2) is an important cytokine released from activated T lymphocytes, which activated lymphokine actived killer cells and natural killer cells , and promoted cytokine production of helper T Cells and natural killer cells , and stimulated T cell growth in vitro and so on . It plays a important role in body immune regulator.

白细胞介素2主要是由激活的T淋巴细胞产生的一类重要的细胞因子，具有激活淋巴因子活化的杀伤细胞和自然杀伤细胞，刺激T辅助细胞和自然杀伤细胞产生细胞因子和促进细胞因子的繁殖以及刺激T细胞在体外生长等功能，因此它是在免疫调节中有重要作用。

Methods Blood samples of fifty-two patients who underwe n t open heart surgery with CPB were collected from right internal jugular vein at p oints as pre-CPB, rewarming, aortic declamping, 6 hours and 24 hours after CPB. Cytokines, iNOS, S-100 and NSE were assayed accurately. In addition, its corre lation between them were also analysed.

方法于 CPB前、复温即刻、主动脉开放和 CPB后 6、2 4小时采集 5 2例心脏病患者颈内静脉血，检测 S- 10 0蛋白和 NSE的浓度，并将其与炎性细胞因子白细胞介素- 6 (IL- 6 )、白细胞介素- 8(IL- 8)、肿瘤坏死因子-α和诱导型一氧化氮合成酶的浓度变化进行相关性分析。

Methods Explore the optimal concentration of phurbol-12-myristate-acetate and calcium ionophore (A23817) inducing time, and optimal concentration of biotinyl sheep anti mouce IgG (bio-SAM-IgG) and horse radish peroxidasestreptavidin. The CD4(superscript +) cell enriched from peripheral blood mononuclear cells using solid phase anti-CDs monoclonal antibodies were induced by PMA and A23817 under influence of monensin and harvested in vary hours.

从健康人外周血单个核细胞中富集CD4细胞，加入莫能霉素，用不同浓度的佛波醇酯和钙离子载体(A23817)诱导CD4细胞不同时间，比较其胞内表达白细胞介素－2(IL-2)/白细胞介素－4(IL-4)的细胞百分率，确定最适诱生条件；用不同稀释度的IL-2McAb、IL-4McAb、不同浓度的生物素化羊抗鼠IgG(bio-SAM IgG)和辣根过氧化物酶标记的链霉亲和素作棋盘配比试验，确认McAb、bio-SAM IgG和HRP-SA的最适浓度，根据上述结果建立了检测细胞内细胞因子的BSA-ICC法。

Other measured markers, including stress hormones(cortisol,adrenocorticotropic hormone, growth hormone) in serum,lymphocyte subsets in peripheral circulation,cytokines(interleukin-1β,tumor necrosis factorαand interleukin-10) and glutamine in serum,seemed to be not effective to estimate the role of GI of the sports drinks in current study.

6本研究的其它测试指标，包括血清应激激素(皮质醇、促肾上腺皮质激素和生长激素)、外周血循环中淋巴细胞亚群(T细胞、B细胞和自然杀伤细胞)、血清细胞因子(白细胞介素-1β、肿瘤坏死因子α和白细胞介素-10)和谷氨酰胺似乎对评价运动饮料的GI的作用没有效果。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。