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Methods: The mice for experiment were immunizied with subcutaneous injection of type Ⅱ collagen to induce arthritis after ovariectomy. Severity of joint swelling, radioimmunoassay of serum estradiol (E2),osteocalcin and tumor necrosis factor, and pathological changes of joint, including changes on synovia, articular cartilage and bone, were observed once weekly.

切除小鼠卵巢后,Ⅱ型胶原皮下注射以诱导关节炎;每周1次观察小鼠的关节肿胀程度;组织切片光镜下观察小鼠滑膜、关节软骨及骨的改变;放射免疫法检测小鼠血清雌二醇、骨钙素、肿瘤坏死因子的变化。

Upon thrombogenic and inflammatory challenges, P-selectin is rapidly expressed, by exocytosis, on activated platelets and stimulated endothelial cells.

当细胞受到凝血酶原或炎症因子刺激后,P-选凝素会迅速地通过外排表达在活化的血小板和内皮细胞的表面。

Groups of 16,20mg significantly increased the level of hormones of serum, such as insulin,growth hormone, triiodothyronine(T3),thyronine(T4except the group of 16mg),insulin-like growth factor-1 (IGF-1),but there was no significant effect on the level of serum glucose.3 , All dosage can significantly increase the crude protein(except the group of 20mg) and significantly decrease crude fat (p.05);and they had significanteffect on some parameters of body stature, such as length of body slope, length of chest bone, girth of chest, pelvic breadth, metatarsus length, metatarsus girth.

不同剂量的G98均能提高肉鸡的激素水平,其中16、20mg/Kg的两个剂量组能显著性提高血清中胰岛素、生长激素、类胰岛素生长因子-1(IGF-1)、三碘甲腺原氨酸(T_3)、甲状腺素(T_4,16mg/Kg剂量组除外)的水平;但对血糖水平没有显著性影响。

And then,the soluble target protein was purified with Ni-NTA column,and its C-terminal was sequenced with mass spectrum analysis.13 amino acids of C-terminal is identical to the Plasmodium falciparum TCTP when blasted in GenBank. Plasmodium falciparum ; Translationally controlled tumor protein ; Cloning expressing

虽然报道认为TCTP具有钙结合、金属内环境稳定、细胞内信号传导、作为IgE依赖性组胺释放因子、作为青蒿素类药物受体蛋白(Bhisutthibhanet al。,1998)和在约氏恶性疟原虫青蒿类药物抗性系中过表达等功能,但其具体生物学功能尚待进一步研究阐明

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1 (IGF-1) and the intervention effect of HMGcoA reductase inhibitor, atovastatin and immune supppressor, rapamycin.

目的:探讨氧化低密度脂蛋白,胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1(IGF-1) and the intervention effect of HMG-coA reductase inhibitor, atovastatin and immune supppressor .rapamycin.

目的:探讨氧化低密度脂蛋白,胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Endothelial celllineage was identified by von Willebrand factorexpression and Ulex europous agglutinin I binding capacity.

用von Willibrand因子表达及Ⅰ型凝集素结合能力鉴定内皮细胞。

Endothelial celllineage was identified by von Willebrand factorVwfexpression and Ulex europous agglutinin IREA-I binding capacity.

用von Willibrand因子vWF表达及Ⅰ型凝集素UEA-I结合能力鉴定内皮细胞。

Urotensin II is a potent vasoconstrictive peptide and involves in hypertension and atherosclerosis.

加压素是一种血管收缩促进因子,可能参与高血压和冠状动脉硬化症的形成。

Aim: To study the effects of angiotensin receptor antaganist-valsartan on vascular hypertrophy、vasomotion function and aorta vascular smooth muscle cell EGF precursor mRNA expression in spontaneously hypertensive rats.

目的:本文探讨血管紧张素受体拮抗剂-缬沙坦对自发性高血压大鼠血管结构、功能以及主动脉血管平滑肌表皮生长因子前体 mRNA表达的影响。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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