素因子

Methods This study consisted of 125 patients with gastric cancer who were divided into two groups: cachectic and noncachectic.

目的 探讨胃窦癌病人血清细胞因子白细胞介素1、IL6 和IL8的水平与恶病质发生的关系。

Histidine and carnosine post-treatments significantly up-regulated the expression of catalase mRNA, and down-regulated mRNA expression of IL-6 and TNF-alpha.

随著组胺酸或肌的摄取浓度增加，会向上调控增加过氧化氢mRNA的表现，并向下调控介白素-6和肿瘤坏死因子-alpha的mRNA表现。

However, it is not known how orthodontic force influences the function of cementoblast and what is the relationship between the function change of cementoblast with root resorption. So we studied the effect of mechanical stimuli on root resoption by examining the expression OPG and RANKL and exploring the related signal transduction pathway in cementoblast. Methods: Cementoblasts OCCM30 were cultured in DMEM with 10% FBS for 48 hours and starved in DMEM with no FBS for 24 hours, then subjected to mechanical strain by four-point bending system with tension and compression stress at 2000μstrain at 0.5Hz frequency. The flow cytometry was used to examine the cell cycle and proliferation activity after 3h, 6h, 12h, 24h loading respectively. OPG and RANKL mRNA were analysed with real time quantitive RT-PCR after the same loading period as FCM.

本课题利用四点弯曲力学加载系统，采用流式细胞术、实时荧光定量PCR、Western免疫印迹等方法，研究体外培养的成牙骨质细胞株OCCM-30在不同力学环境中增殖活性的变化，以及其表达骨保护素和破骨细胞分化因子的mRNA的变化，探讨应力刺激对成牙骨质细胞表达破骨细胞分化调控蛋白的影响，并通过对应力刺激下成牙骨质细胞分裂原活化蛋白激酶家族中的ERK1/2、P38MAPK活性的变化及其与OPG、RANKL基因表达变化关系的研究，对力学刺激调节破骨细胞分化调控蛋白的相关上游信号转导通路进行初步探讨。

A number of studies have suggested that apoptosis and its regulation plays an important pathogenic role in the chemoresistance of human melanoma.

现有研究已证实凋亡及其调节因子是决定恶性黑素瘤耐药的重要机制。

Methods: A total of 80 patients in coronary heart disease with normal cholesterolemia were selected and randomly to Xuezhikang group and pravastatin group . Xuezhikang was given 0.6 Bid po. pravastatin was given 40mg Qd po.adiponectin and TNF-α of all patients were analyzed at baseline,12 weeks after given Xuezhikang and pravastatin in trail patients.

入选80例血脂正常冠心病患者随机分为血脂康组和普伐他汀组，血脂康组给予血脂康0.6日二次口服，普伐他汀组给予普伐他汀40mg 日一次口服，在用药前及用药12周后分别测定血清脂联素及肿瘤坏死因子水平。

Tissue composition analysis, nutrient enrichment and starvation treatments, bioassay and in situ extracellular alkaline phosphatase activity determination showed that growth of Sargassum duplicatum, Codium edule and Ulva latuca were limited by phosphorus during the early growth period while nitrogen during the fast growth period. Growth of Enteromorpha linza, Gracilaria coronopifolia and Laurencia papillosa were limited by phosphorus.

南湾及眺石海水优养化可能是造成大型海藻单位面积生物量明显增加的原因，藻体营养分析、室内营养盐添加与不添加处理、bioassay及insitu 细胞外磷酸分解酵素活性证明重缘叶马尾藻、食用松藻及大石莼的营养盐限制因子在初期是磷而快速生长期是氮而浒苔、伞房龙须菜及乳头凹顶藻是磷。

Objective: To study the effect of Crocin on the expression of VEGF-C in transitional cell carcinoma of bladder T24 cell. Methods: 24 cells were treated with Crocin.

目的：研究藏花素对膀胱移行细胞癌T24细胞血管内皮生长因子C(Vascular endothelial growth factor， VEGF-C)表达水平的影响。

As a new messenger factor,carbon monoxide can activate soluble guanyl cyclas,relax angio-smooth muscle,prevent platelet from aggregation and inhibit angio-smooth muscle cells proliferation,therefore it can maintain normal blood stream in coronary artery.

一氧化碳是一种新的信使因子，通过激活可溶性鸟苷酸环化酶，舒张血管平滑肌，抑制血小板聚集和抑制血管平滑肌细胞增殖，从而恢复冠状动脉的正常血流。血红素氧合酶通过其抗动脉粥样硬化作用对冠状动脉起保护作用。

objectivein order to study il-1βand tgf-β1 have what effects on sd rat chondrocyte cell.methondsdifferent dosis of il-1βand tgf-β1 was used to deal chondrocyte cell 48 hours.then aggrecan and collagen ii of those celluar and the control group were detected by immune-histochemistry.

目的：研究人白细胞介素-1β（il-1β）和转化生长因子-β1(tgf-β1)对体外培养的sd大鼠肋软骨细胞功能的影响。

The treatment group was given Qizhengxiaotong Emplastrum(0.75 g/kg),and the model group and blank group were given normal saline solution(0.5 mL/each)externally for 5 days on 10th day after the establishment of ...

末次给药后测量各组小鼠的痛行为，包括机械性痛觉超敏和热刺激痛觉过敏；将小鼠股骨进行X线摄片，影像学评估骨破坏；用免疫组化法检测各组局灶皮肤组织肿瘤坏死因子α、内皮素-1(ET-1)、白介素-1β(IL-1β)水平及脊髓后角P物质受体、c-fos及GFAP阳性反应神经元的表达。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。