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Xylanases are a group of enzymes that break down xylans into xylooligosaccharides, xylose and arabinose, and thus are of high potential for use in feed, paper making and food industry.

木聚糖酶以内切方式作用于木聚糖分子中β-1,4-木糖苷键,可将木聚糖水解为木二糖和木二糖以上的低聚木糖,以及少量木糖和阿拉伯糖,在饲料、造纸和食品等行业具有广阔的应用前景。

Thin-layer chromatography analysis showed that the xylanase released mainly xylobiose and xylotriose from birchwood xylan. The hydrolysis of xylotriose appeared to proceed via transglycosylation, since the xylobiose was the predominant product.

薄层层析结果显示该酶水解桦木木聚糖的主要产物是木二糖和木三糖,并且能够通过转糖苷作用将木三糖转化为木二糖。

The inhibitory effect of SCS on α-glucosidase activity is similar to those of acarbose without significantly difference.

SCS对α-葡萄糖苷酶的抑制作用与"拜糖平"的抑制效果没有显著差异;其性质属竞争性抑制,不同与其它主要的α-糖苷酶抑制剂。

Guanosine A nucleoside present in DNA and RNA and consisting of guanine linked to D-ribose via a B-glycosidic bond.

鸟苷:是存在于 DNA 和 RNA 中的一种核苷,由鸟嘌呤通过 B 糖苷键连接 D —核糖所组成。

Glucosidase deficiency disease is a rare genetic disorder in which the lysosomal enzyme α-glucosidase is markedly reduced and leads to accumulation of glycogen in various tissues. Its clinical features include massive enlargement of the internal organs, skeletal muscle weakness and hypotonia, and respiratory insufficiency.

阿法-糖苷酶缺乏之全身性糖原质病是一种少见的遗传性疾病,此病主要是因为缺乏阿法-糖苷酶而造成过多的糖原质堆积在各种组识中,导效患者在临床上会有内脏扩大、肌肉无力和呼吸不足等症状。

The monosaccharides in LBP-4 identified by GC were xylose , galactose , mannose , Rhamnose , glucose and arabinose with the molar ratio of 4. 45: 1. 20: 1. 0: 0.98: 0.90: 0.85. The content of calcium, magnesium, zinc and iron in LBP-4a were 127. 9070mg·g〓, 32. 3953mg·g〓, 0.3845mg·g〓 and 0.2930mg·g〓, respectively. The content of galacturnic acid in LBP-4a was 55. 45% while the content of protein is 3. 80%. According to IR spectra, it contains -COOH group,-NH- roup,-OH group,-NH〓 group and β-D-glucose. The backbone of sugar residues chain in LBP-4a were contained 1→6 indican bond according to periodate oxidation and the results of β-elimination reaction indicated that the chain of polysaccharides and protein were connected by O-linked chemical bond. The photograph of LBP-4a got by laser scanning confocal microscope and scanning electron microscope showed that the LBP-4a combined both with each other and with itself in its crystalloid. The crystalloid was flake and anisotropic.

由LBP-4a的红外光谱图知:LBP-4a中含有-COOH、-OH和-NH〓或-NH-基团,糖链中含有β-D-吡喃葡萄糖;高碘酸氧化实验知LBP-4a糖链中不具有连二羟基和连三羟基结构的单糖残基:具有连二羟基结构的单糖残基:具有连三羟基结构的单糖残基=57.0:16.2:1,六碳糖残基的连接中含有1→6连接的糖苷键;通过β消去反应证明LBP-4a中多糖链和氨基酸间为-O-型连接;由激光扫描共聚焦显微镜和扫描电镜对LBP-4a结晶观察结果推测:LBP-4a结晶中同时存在分子间和分子内结合的现象,LBP-4a分子相互结合时,并不是无规则的相互缠绕形成无规线团结构,而是形成片层结构,并且LBP-4a结晶可能具有各向异性的性质。

The invention discloses a 3, 5-2-0-(4-chlorobenzene chlorobenzene)-2-deoxidising- D-red-furanoside that contains alpha body and beta body. The method includes the following steps: dissolving chlorine indicant into tetrahydrofuran, quickly adding to alcoholic solutioin, whisking and reacting, after reacting, vacuuming and steaming solvent to gain mixture of alpha body and beta body, taking separation by column chromatography to gain separated alpha body and beta body.

本发明公开了一种3、5-二-O-(4-氯苯甲酰基)-2-脱氧-D-赤-呋喃糖苷,它具有式表示的α体和式表示的β体,制备方法采用在室温下,将氯糖苷溶于四氢呋喃中,然后快速加入到醇溶液中,搅拌下进行反应;反应结束,减压蒸掉溶剂,得到白色固体,将该固体用石油醚溶解,过滤除去不溶物,再次减压蒸去溶剂,得到白色α体和β体的混合物,用柱色谱法进行分离,得到单独的α体和β体。

METHODS: Based on the antitumor activity and structural feature of 8-chloroadenosine and retinoic acid, modifications were made at positions 5′ and 8,substituted cinnamoyl and benzoyl groups were bound at 8 position through amido and ester bonds, sulfonation and nitrosation at 5′-OH and its direct chlorination were conducted.

对腺苷的8位和8-Cl-腺苷的糖环羟基进行了结构改造,以酰胺键和酯键在腺苷的8位连接了具共轭基团的肉桂酰基和苯甲酰基,得到腺苷的维甲类似物;对8-Cl-腺苷的5′-羟基进行了甲磺酰化,硝基化以及氯代反应,得到了它的衍生物。

Methods Determination of DNJ by derivatization with 9-fluorenylmethyl chloroformate and followed by reversed-phase high-performance liquid chromatography and a fluorescence detector; the inhibitory curves on α-glucosidase at the enzymatic level and the activities to α-aglucosidase in vitro were observed in the everted sac experiment.

以氯甲酸药甲酯柱前衍生RP-HPLC荧光检测法对DNJ进行分析;在酶水平测定样品的α-糖苷酶抑制曲线,在离体水平用反转肠囊实验测定样品的α-糖苷酶抑制活性。

The recent synthesis progress of glycoconjugate is reviewed,including the various methods of the glycosidic bond formation by chemical synthesis and the synthesis strategies of novel complex glycoconjugates,such as glycopeptides,glycoproteins and glycolipids .

本文介绍近年来各种糖缀合物化学合成的研究进展,包括各种糖苷键的化学合成方法以及各种特殊复杂糖缀合物,如糖肽、糖蛋白、糖脂的化学合成策略。

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