糖脂

The erythritol is produced industrially by Zhongshi Gerui biotechnology Co., Ltd., Zibo by means of utilizing Candida lipolyti developed by China Food Fermentation Industry Inst. And with the preservation number of CGMCC No.1431 as the high erythritol yield spawn and deep liquid fermentation of glucose. The erythritol is used as functional sweetening agent in sugar substitute for diabetics, low calorie sugar, low calorie beverage, low calorie cake, low calorie candy, low calorie milk product, etc.

具体是指淄博中食歌瑞生物技术有限公司与开发出赤藓糖醇高产菌种――解脂假丝酵母 Candida lipolytic 的中国食品发酵工业研究院合作，利用保藏编号为 CGMCC No.1431的解脂假丝酵母 Candida lipolytica 菌种，用葡萄糖深层液态发酵，工业规模制取的赤藓糖醇；作为功能性甜味剂，在下述产品中的应用：糖尿病人代用糖，低热量佐餐用糖，低热量饮料，低热量糕点，低热量糖果，低热量奶制品和低热量冰激淋或低热量雪糕或低热量冰糕。

Using peptide hydrolysis combined with amino acid analysis, sugar alcohol acetylation combining with GC/MS, fattic acid methyl esterization combining with GC/MS and other technical means it was identify carbohydrate in the bioemulsifier mainly was D-mannose, and main amino acids were glutamic acid, aspartic acid, alanine, and main fattic acids that composed lipid was hexadecanoic acid, octadecenoic acid, and octadecanoic acid.

利用肽水解结合氨基酸分析、糖醇乙酰化结合GC-MS、脂肪酸甲脂化结合GC-MS等技术手段鉴定乳化剂中糖主要为D-甘露糖；主要氨基酸为谷氨酸、天冬氨酸、丙氨酸；构成脂的主要脂肪酸为十六烷酸、十八烯酸和十八烷酸。

Water, Cyclomethicone, Glycerin, Sd Alcohol 40-B (Alcohol Denat.), Propylene Glycol, Melia Azadirachta Leaf Extract, Lecithin, Arctium Lappa Root Extract, Xylitol, Lactitol, Alpha-Glucan Oligosaccharide, Lactoferrin, Potassium Thiocyanate, Glucose Pentaacetate, Glucose Oxidase, Lactoperoxidase, Glycoproteins, Panax Ginseng Root Extract, Equisetum Arvense Extract, Hydrolyzed Milk Protein, Peg-8, Caprylyl Glycol, Sebacic Acid, Sodium Polyacrylate, Betula Alba Bark Extract, Cupressus Sempervirens Leaf Extract, Hamamelis Virginiana Extract, Avena Sativa Meal Extract, Humulus Lupulus Extract, Silk, Nylon-12, Polyacrylamide, Polymethyl Methacrylate, Butylene Glycol, Salicylic Acid, Lauryl Methacrylate/Glycol Dimethacrylate Copolymer, Tocopheryl Acetate, C13-14 Isoparaffin, Laureth-7, Triethanolamine, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Phenoxyethanol, Chlorphenesin, Benzoic Acid, Methylparaben, Fragrance, Titanium Dioxide

水，环甲硅脂，甘油，Sd Alcohol 40-B，丙二醇，印度楝树叶萃取，卵燐脂，牛蒡根萃取，木糖醇，乳糖醇，α-葡低聚糖，乳铁蛋白，硫氰酸钾，葡萄糖五乙酸酯，葡萄糖氧化酶，乳过氧化物酶，糖蛋白，人参根萃取，问荆萃取，水解牛奶蛋白，聚乙二醇-8，辛乙二醇，癸二酸，聚丙烯酸酯钠，白桦萃取，丝柏叶萃取，金缕梅萃取，燕麦萃取，啤酒花萃取，丝，尼龙－12，聚丙烯醯胺，聚甲基丙烯酸甲酯，丁二醇，水杨酸，甲基丙烯酸十二酯，醋酸盐维他命E，C13-14 异烷烃，月桂醇聚醚-7，三乙醇胺，山羊胶，丙烯酸/C10-30烷基丙烯酸聚合物，苯氧乙醇，氯苯甘醚，苯甲酸，羟苯甲酯，香料，二氧化钛

The result indicated that ZXTMN group excelled the western medicine in the aspects of ameliorating symptom and hemodynamics, adjusting sugar and lipid metabolism, and reducing urine albumin and pltaelet adhesiveness and aggreagtion. The mechanism, which ZXTMN prescription could protect renal function, probably was (1) decreasing the level of sugar and glycosylated ferrohemoglobin;(2) decreasing AR activity of erythrocyte, improving SDH activity of erythrocyte, reducing accumulation of sorbitol in the erythrocyte, thus ameliorating the polyol metabolism;(3) accommodating lipid metabolism;(4) ameliorating coagulation, gathering, thick and mucosity of patient blood.

结果表明，止消通脉宁治疗组明显优于西药对照组，在改善症状，调整糖、脂代谢，减少尿白蛋白，改善血流变，降低血小板粘附和聚集等方面具有显著的疗效，分析其治疗早期DN的机制可能有以下几个方面：（1）降低血糖和糖化血红蛋白；（2）降低DN患者红细胞AR活性、提高SDH活性、减少红细胞内山梨醇积聚从而改善多元醇代谢；（3）调节脂质代谢；（4）改善DN患者血液凝、聚、浓、粘状态，抑制血小板的粘附聚集，从而改善肾脏微循环，保护肾功能。

This thesis conclude 4 parts: 1 、 The change and effecting factors of plasma adiponectin level in old subjects with abnormal glucose tolerance; 2、 The distribution of adiponectin receptors in Wistar rat; 3、 The effect of fat-fed and pioglitazone on mRNA expression of adiponectin with its receptors...

本研究共包括以下四部分内容：1、老年糖耐量异常人群中脂联素的改变及其影响因素；2、脂联素受体mRNA在Wistar大鼠体内的分布；3、高脂饲养以及吡格列酮对大鼠脂肪组织脂联素及其受体表达的影响；4、吡格列酮对不同浓度脂肪酸培养的HepG2细胞脂联素受体mRNA表达的影响。

Methods: 1. Rats in the study were divided into six groups: normal control group, hyperlipidemia group (fed with high-cholesterol diet), atherosclerosis group (vitamin D〓 intramuscular injection, endothelium denudate and fed with high-cholesterol diet with vitamin D〓), L-arginine group (besides treatment as atherosclerosis group, 2.25％ L-arginine was added in the drinking water), chitosan group (besides treatment as atherosclerosis group, 5％ chitosan was added in the diet), simvastatin group (besides treatment as atherosclerosis group, 0.03％ simvastatin was added in the diet). The study lasted 90 days.

1。实验大鼠分为6组：正常对照组、高脂血症组、动脉粥样硬化组(维生素D〓肌肉注射加动脉球囊损伤手术加含维生素D〓的高脂饲料饲养)、L-精氨酸组(动脉粥样硬化组基础上饮水中加入2.25％L-精氨酸)、几丁糖组(动脉粥样硬化组基础上饲料中加入5％几丁糖)、辛伐他汀组(动脉粥样硬化组基础上饲料中加入0.03％辛伐他汀)，90天后取标本检测。2。

Objective To make high glucose and hyperlipidemias models and study on relation between disturbance of lgucose and lipide metabolism and DM.

目的通过高糖、高脂血症动物模型，观察糖、脂代谢紊乱对机体的影响及与糖尿病的关系。

The treatment comparison by using Chinese TANG Kidney capsule and Western medicine TANG SHI PIN showed: the kidney capsule can lower the values of the blood sugar, blood fat, series of micro-protein un urine and carbon monoxide in plasma, thus the function of kidney can be improved, and prolong the process of deadness and hardening of the affected kidney small cell fibre.

利用该模型选择中药糖肾胶囊与西药糖适平对照治疗研究，结果显示：糖肾胶囊能降低糖尿病肾病大鼠的血糖、血脂、尿素氮、肌酐、尿系列微量蛋白及血一氧化氮等指标，从而减轻糖尿病肾病大鼠肾小球的高灌注高滤过，降低糖化血红蛋白含量，减轻非酶糖基化，改善肾功能，降低血脂、内皮素、调节血栓素、前列腺素水平，有抗脂质过氧化损伤的作用。

Compared with these of fat-fed group,the body weight,blood glucose levels after oral glucose and the glucose area under curve,40min and 90min blood glucose levels after insulin injection subcutaneously and the glucose area under curve in the insulin tolerance test,the fasting serum insulin,insulin resistance index,serum cholesterol,triglyceride and lower density lipoprotein cholesterol decreased.

n-6脂肪酸组从第1~10周体重均较高脂组明显减轻，糖负荷后血糖和糖耐量试验中葡萄糖曲线下面积、皮下注射胰岛素后40 min9、0 min血糖及胰岛素耐量试验中葡萄糖曲线下面积、血清胰岛素、胰岛素抵抗指数、血清胆固醇、甘油三酯和低密度脂蛋白含量均较高脂组明显降低

Objective:To make animal models of "high glucose"and "hyperlipidemia" and observe the effects of high glucose and hyperlipidemia on rats.Method:Vascular function detection,tissue culture and radioactivity analysis methos were used.

复制高糖、高脂血症动物模型，采用血管功能检测、组织培养及放射免疫分析方法观察高糖、高脂对大鼠机体的综合影响并探讨其发病机制及治疗原则。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。