糖脂

The lifestyle interventional technique including exercises prescription of quantified caloric consumes was used in IG but was not used in CG.The other indexes of caloric intakes and consumes,body measurement index,glucolipid metabolic index and medical costs were observed before and after 6 months in both two groups.

干预组采用定量热卡消耗运动处方在内的生活方式干预技术，对照组常规门诊治疗，随访6个月后观察热卡摄人及消耗、身体测量指标、糖脂代谢指标及医药费用。

The effect of herba TZP on glucolipide metabolism and function of islets of pancreas in experimental NIDDM diabetes mellitus.

结果显示：糖脂平能明显降低模型鼠的体重增长率，明显抑制模型鼠血清甘油三酯的升高。

The improved puberty PCOS-IR rat model has following characteristic:Retained the high androgen syndrome and/or the high LH syndrome as the endocrine characteristics;Simultaneously it had sugar fat metabolism unusual, such as the insulin resistance,the redemptive high insulin blood sickness as well as cholesterol ascension.Has the abdomen obese characteristic----In particular fat pad which around reproductive organ obvious increased;The ovary increased obviously,Ovarian cortex accumulated,the number in ovary pouch expansion graafian follicle were remarkable increased, ovulation suppression.

一、改良青春期PCOS-IR大鼠模型具有以下特征：1、保留了高雄激素血症和/或高LH血症等内分泌特征；同时有胰岛素抵抗，代偿性高胰岛素血症以及总胆固醇升高的糖脂代谢异常。2、具有腹部肥胖的特征——尤其是生殖器周围脂肪垫明显增加；3、卵巢明显增大，皮质增厚，卵巢内囊性扩张卵泡数目显著增加，排卵抑制。

PPAR γ agonist displayed obvious renoprotective action,the mechanism was complicated, it could improve the metabolism of glucose ang lipid, depress blood preasure, protect small vessels endothelium,improve the system activity of blood clotting and fibronolysis, antiinflammation, otherwise the action was more obvious with the time passed, at the early stage the effective was better,so encourage the patients to take the medicine earily; when the patients with the mediate reanl function failure, Avandia did not display significantly renoprotective action, side reaction had no difference compared to the control group,was not necessary to regulate the dose of Avandia.But because of the sample size was small, we needed a biger sample to confirm the results. We confirmed that Prol2Ala had no difference in control case,diabetic nephropathy group and diabete group,In diabetic group and diabetic nephropathy group, Ala carriers compared to noncarrier all kinds of biochemical indicators were not different,Prol2Ala did not have association with diabete and diabetic nephropathy. But because of the sample size was small, weneeded a biger sample to confirm the results.

PPARγ激动剂对糖尿病肾病具有明显的保护作用，保护作用的机制是多方面的，除了改善糖脂代谢，降低血压外，还具有保护小血管内皮，改善凝血和纤溶系统活性，抗炎症等多方面的作用，且作用随着用药时间的延长而日趋明显，在疾病的早期应用效果更佳，故提倡早期用药；对伴有慢性肾功不全的患者，罗格列酮对肾脏靶器官的保护作用显现的并不明显，但副作用与对照组无明显差异，不用根据肾功情况调整用药，但由于样本量较小，上述结论尚需大样本进行进一步证实；本实验研究得出Prol2Ala变异在健康对照组、糖尿病组及糖尿病肾病组均无显著差异，糖尿病组及糖尿病肾病组临床各生化指标与Prol2Ala变异亦无相关性，Prol2Ala与糖尿病及糖尿病肾病不相关。

Objective : To investigate in endocringical and metabolic characteristics on polycystic ovary syndrome with/without obesity.

目的：探讨肥胖与肥胖型多囊卵巢综合征在生殖内分泌、糖脂代谢方面的差异。

Pioglitazone is a thiazolidinedione that ameliorates insulin resistance and improes glucose and lipid metabolism in type 2 diabetes mellitus.

吡格列酮是一种噻唑烷二酮类药物，可以改善胰岛素敏感性并且改善2型糖尿病的糖脂代谢。

Pioglitazone is a thiazolidinedione that ameliorates insulin resistance and improves glucose and lipid metabolism in type 2 diabetes mellitus.

吡格列酮是一种噻唑烷二酮类药物，可以改善胰岛素敏感性并且改善2型糖尿病的糖脂代谢。

Compared with these of fat-fed group, the body weight, blood glucose levels after oral glucose and the glucose area under curve, 40min and 90min blood glucose levels after insulin injection subcutaneously and the glucose area under curve in the insulin tolerance test, the fasting serum insulin, insulin resistance index, serum cholesterol, triglyceride and lower density lipoprotein cholesterol decreased, the fasting serum leptin, high density lipoprotein cholesterol and C18:2 were significantly increased in N-6 PUFAs group.

n-6脂肪酸组从第1~10周体重均较高脂组明显减轻，糖负荷后血糖和糖耐量试验中葡萄糖曲线下面积、皮下注射胰岛素后40min、90min血糖及胰岛素耐量试验中葡萄糖曲线下面积、血清胰岛素、胰岛素抵抗指数、血清胆固醇、甘油三酯和低密度脂蛋白含量均较高脂组明显降低；血清瘦素水平、高密度脂蛋白、18碳2烯酸较高脂组明显升高。

Additionally, we had done some work about the modification of lipases andRAMA by sugar-esters.

五个脂肪酶和RAMA经糖脂修饰后，在有机溶剂中的催化活性均有不同程度的提高。

In vivo-induced genes spd_0300, spd_0414, spd_0622, spd_1663, spd_1719, spd_0235, spd_0873, spd_1672 regulated by transformation were screened out and they may participate in the processes such as growth regulation, temperature reception, carbohydrate metabolism, and lipoids metabolism.

筛选出受转化调控的体内诱导基因spd_0300、spd_0414、spd_0622、spd_1663、spd_1719、spd_0235、spd_0873、spd_1672，它们可能参与生长调节、温度感应、糖脂代谢等环节，表明细菌转化可通过调节某些体内诱导基因的表达来增强细菌的毒力。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。