糖脂

Along with the fluconazole solution density rise,the experimental two kind of strain various glucose density is higher,showe d the glucose consumption are less,takes the logarithmof the medicine de nsity,discovered the logarithm the medicine density and each glucose den sity presents the linear relations;Carries on the analysis comparison to under the fluconazole function two kind of strain linear relations,disc overed the relations of the two strains has the nonuniformity.3 Compare the fluconazole induction reaiatance SC5314 strain and sens itive strain compares,its difference gene expression mainly concentrates in:The code proteinase body and the protein hydroltyic enzyme gene,in the code sugar fat metabolism process is connected the protein gene,the cell cycle correlation gene,the duplication and the translation adjustme nt correlation gene,the stress response correlation gene,the line plast ochondria correlation gene,the cell wall function related gene.4 Candida albicans SC5314 induction resiatance strain was processed b y Xianglian solution,its expression change gene mainly is:Code stress re sponse family protein gene,biomembrane relevant gene,a code proteinase body gene race,code cell cycle related protein gene,duplication and tra nslation adjustment related protein gene.5 The clinical reaiatance strain Candida albicans was processed by Xi anglian solution,its expression change gene mainly is:Codes the hot sho ck protein gene,the serine/threonine protein activating enzyme gene,the proteinase body family gene,the regulation copies and translates the ge ne.

随着氟康唑药液的浓度上升，试验的两种菌株各孔葡萄糖浓度越高，说明葡萄糖消耗越少，经过药物浓度取对数后进行分析，发现取对数后的药物浓度和每孔中葡萄糖浓度者呈现线性关系；对氟康唑作用下的两种菌株的线性关系进行分析比较，发现对两种菌株作用具有不一致性。3氟康唑诱导的耐药SC5314菌株与诱导前的敏感株相比，其差异基因表达主要集中在：编码蛋白酶体及蛋白水解酶的基因，编码糖脂代谢过程中相关蛋白的基因，细胞周期相关基因，转录及翻译调节相关基因，应激反应相关基因，线粒体相关基因，细胞壁功能相关基因。4白念珠菌SC5314诱导耐药株经香莲外洗液作用后，其表达变化的基因主要是：编码应激反应家族蛋白的基因，生物膜相关性基因，编码蛋白酶体基因一族，编码细胞周期相关蛋白基因，转录及翻译调节的相关蛋白基因。5白念珠菌临床耐药菌株经香莲外洗液作用后，其表达变化的基因主要是：编码热休克蛋白基因，丝氨酸/苏氨酸蛋白激酶基因，蛋白酶体家族基因，调控转录及翻译基因。

Objective: The purpose of our studies are gaining a better insight into the effect of genistein on mesangial cell"s phenotype change and ECM expression plus degradation under DN circumstances.We add genistein with different concentrations in high glucose cultured rat mesangial cells;feed DM rats with the single concentration genistein for different days;to explore the expression of SMemb,the mark of mesangial cell"s hypertrophy phenotype change;to examine the synthesis of Fn as well as the change of the balance between MMP-2 and TIMP-l;to comprehend its effect on renal pathological changes of DM rats and some related factors;trying toexplore the possible mechanisms.Through these studies,we will have some information about the experimental value of genistein in DN field.

目的：为了研究金雀异黄素对DN环境下大鼠MC肥大表型转换标志物SMemb和ECM分泌及降解的影响，我们拟在细胞水平以不同浓度的金雀异黄素作用于高糖培养下大鼠MC，在动物水平以同一浓度的金雀异黄素作用于DM大鼠不同时间，观察细胞表型转换标志物SMemb、ECM主要成分Fn、ECM降解酶系统基质金属蛋白酶—2(MMP-2)／基质金属蛋白酶抑制剂—1(TIMP-1)表达的变化，同时观察金雀异黄素对DM大鼠肾脏病理及影响肾脏病进展的糖脂代谢紊乱的影响，并进一步探讨金雀异黄素发挥作用的可能机制；为明确金雀异黄素在DN治疗中的地位及意义提供实验依据。

We describe herein that newly developed ether-containing ionic liquids dissolve carbohydrates,and this unique "sugar-pgilic" property allows formation of glycolipid bilayer membranes in ionic liquids.

我们描述此处新开发醚载离子液体溶解碳水化合物，这独一无二的"糖pgilic "属性允许形成糖脂双分子膜的离子液体。

5MN/m.(2) the biosurfactant was glycolipid type which was consisted of monosaccharides, disaccharides or trisaccharides group and fatty acid group which were combined by ester bond.

2产生的生物表面活性剂为糖脂类型，糖基通过酯键与不同链长的脂肪酸相连。

G. biomimetic modification of biomaterials surface for improving cells affinity, carbohydrate cluster, glycolipid and protein modifying biomaterials surface in order to enhance cells specificity recognition, self2assembly of materials to modify surface topography1

基于生物材料对细胞生长的影响，本文提出了生物材料表面生物仿生化以提高细胞亲和力，糖链团簇、糖脂质及材料表面蛋白质修饰以提高细胞特异性识别，材料表面的自组装修饰以改善表面形态等观点。

LeY is abnormally expressed by 60~90% percent of cancers of epithelial origin.

含LeY的糖蛋白或糖脂可分泌或脱落至血液中。

Some of them contain sphingomyelin and more glycosphingolipids than others but contain only low content of cholesterol.

我们认为脂筏具有多样性，糖脂丰富而胆固醇缺乏的膜微区可能是其中的一种。

Objective To study the effect of stress on plasma sialic acid level and on the immunofunction.

已证明SA是细胞膜糖蛋白和糖脂的重要结构和功能成分，是细胞膜上负电荷的来源，与细胞的转变、增殖分化，免疫调控等功能密切相关［1～3］。

Objective To investigate the mechanism of β-cell dysfunction induced by glucolipotoxicity in high fat-fed obese rats.

目的 探讨糖脂毒性引起高脂肥胖大鼠胰岛β细胞功能障碍的可能机制。

Their findings help reveal how the enzyme prepares to assemble the bacteria's sugar-coating by plucking sugars from a fat-sugar package known as lipid II.

他们的发现帮助显示酶是如何通过从名为 lipid II 糖脂包中移出糖准备组装细菌的包糖衣。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。