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In order to further investigate the relationship of SP and ESCs, we design two level experiments —in vitro and in vivo. In vivo, firstly, We establish the nomal rat full-thickness wounds model, and employ integrin β1 keratin 19(K19)、 keratin 15(K15)、 Brdu as ESCs markers to conform the existence of ESCs in the granulation tissue of Group Capsaicin (rats were subcutaneously injected capsaicin pre-injury to damage sensory neuron and block the secretion of neuropeptides), Group Control, and Group SP (rats were injected SP in the wound postinjury). Secondly, as diabetic skin lacking of SP due to extensive pathological changes of sensory ending, we make a hypothesis:one of the main reason of unhealing wounds on diabetic patients could be insufficient SP which lead to fewer ESCs recruitment around wounds.

在此基础上,为进一步验证P物质促进表皮干细胞向肉芽组织中募集这一重要发现,本研究首先利用β1整合素、K19、K15等干细胞标记物以及干细胞慢周期性的特点,分别在体观察了正常皮肤伤口愈合过程中SP组、辣椒素组采用特异性感觉神经毒性药物辣椒素(capsaicin皮下预注射化学性除去感觉神经从而阻止神经肽分泌、对照组肉芽组织中表皮干细胞分布特点;其次,糖尿病患者皮肤存在周围末梢神经的损伤和神经肽含量的下降,这是否会导致糖尿病皮肤伤口创缘表皮干细胞募集不足,继发伤口难愈?

She is especially good at the management of the eyeground diseases, such as ocular fundus bleeding from various reasons, retinal vascular diseases (such as diabetic retinopathy, retinal vein occlusion, retinal artery occlusion, retinal vasculitis etc.) from diabetes mellitus, hypertension, or various inflammation, retinal capillary hemangioma, vitreous hemorrhage caused by various retinal diseases, optic neuritis, ischemic optic neuropathy, retinal detachment, macular diseases (such as age related macular degeneration, central serous chorioretinopathy, central exudative chorioretinopathy etc.), and other complex diseases such as uveitic diseases and glaucoma etc.

特别是对眼底病如各种原因所致眼底出血;糖尿病、高血压、各种炎症所引起的视网膜血管病如糖尿病视网膜病变、视网膜静脉阻塞、视网膜动脉阻塞、视网膜血管炎症等;视网膜血管瘤病以及其他各种视网膜病所致玻璃体出血;视神经炎、视神经缺血、视网膜脱离、黄斑部疾病如老年性黄斑变性、中浆、中渗等及其他疑难病如葡萄膜炎,青光眼等的诊治积累了大量的临床经验。

It is a original work in the world that using these ligands to coordinate with vanadyl cation to form complexes and the study of the structures along with the anti-diabetic properties, thus provide us opportunity to obtain vanadium drug with the properties of lowering blood sugar significantly and low toxicity, the research will benefit the large number of diabeticpatients, the economic and social benefit will be obvious.

上述配体与氧钒离子形成配合物及结构和抗糖尿病功能的研究在世界上属首创工作,使我们有望制备出具有显著降血糖功能且低毒性的钒类药物,为广大糖尿病患者带来福音,产生明显的经济效益和社会效益。

Doctors were gods in the Shetty household, swooping in to save his restaurateur father who suffered from chronic diabetes and fell into diabetic comas several times in the young boy's life.

对谢蒂的家庭来说,医生就是神灵;他开餐馆的父亲患有慢性糖尿病,并数次陷入糖尿病昏迷,谢蒂小时候多次目睹医生赶来拯救父亲的生命。

To study expression of uncoupling proteins homologues in retina of rats. To observe changes of mRNA expression of UCPs and MnSOD in different courses of diabetes.

检测正常大鼠视网膜中UCPs的表达类型,以及UCPs、MnSOD mRNA表达随糖尿病病程的变化,探讨糖尿病性视网膜病变发病的分子机制。

Methods The extracranial carotid arteries and proper palmar digital arteries of 80 patients with type 2 diabetic combine cerebral infarction, 30 patients with type 2 diabetic and 41 healthy collators were detected by colour-Doppler ultrasound ,the relationships between carotid IMT and risk factors of cerebrovascular disease were evaluated .

利用彩色多普勒超声对 80 例 2 型糖尿病性脑梗死患者、30 例单纯糖尿病患者及 41 例性别、年龄匹配的健康对照人群的颈动脉和指动脉进行检测,并分析颈动脉内中膜厚度与脑血管病危险因素间的关系。

Following the deep recognition of DM-2,the develop tendency of new drug study in curring DM-2 changes corresponding.That is treatment from part to all over the body,new drug from direct intervention to enhance self regulation function.

指出随着对糖尿病认识的深入发展,治疗糖尿病创新药物研究的发展趋势也发生了相应的变化,就是从局部治疗到全身综合考虑,从药物外部直接地干预到增强自身调节功能。

The treatment comparison by using Chinese TANG Kidney capsule and Western medicine TANG SHI PIN showed: the kidney capsule can lower the values of the blood sugar, blood fat, series of micro-protein un urine and carbon monoxide in plasma, thus the function of kidney can be improved, and prolong the process of deadness and hardening of the affected kidney small cell fibre.

利用该模型选择中药糖肾胶囊与西药糖适平对照治疗研究,结果显示:糖肾胶囊能降低糖尿病肾病大鼠的血糖、血脂、尿素氮、肌酐、尿系列微量蛋白及血一氧化氮等指标,从而减轻糖尿病肾病大鼠肾小球的高灌注高滤过,降低糖化血红蛋白含量,减轻非酶糖基化,改善肾功能,降低血脂、内皮素、调节血栓素、前列腺素水平,有抗脂质过氧化损伤的作用。

Objective: To observe the effects of Xiaokeping Jiaonang in treating the hyperglycaemia Jimpy mice which was caused by adrenaline and the rabbit of diabetes mellitus which was caused by alloxan; to explore the mechanism in blood rheology and Ang of biochemistry etc.

目的:观察消渴平胶囊对肾上腺素性高血糖小鼠以及四氧嘧啶性糖尿病家兔的治疗作用,探讨消渴平胶囊对肾上腺素引起的高血糖小鼠和四氧嘧啶性糖尿病家兔的治疗作用机制。

It is very important to strengthen the education of diabetic knowledge and correct nursing of foot for the prevention of diabetic foot.

加强糖尿病知识的宣教及足部正确护理,对预防糖尿病足的发生有着非常重要的意义。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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