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Being diabetic longer is easier suffered from chronic syndrome and then engendering diabetes gangrene and acrodynia gangrcne that is mostly reflecting on erura.

糖尿病并发症主要是血管并发症,高血压是慢性并发症发展的重要危险因素,糖尿病病程越长,慢性并发症越容易发生,形成糖尿病性;责疡和肢端坏疽,以下肢最为多见。

Methods:All of 40 male Sprague-Dawley rats were divided into 3 groups:control group(group A, n = 10), diabetic group for 4 weeks(group B, n = 14), and diabetic group for 12 weeks(group C, n = 16). The diabetes model was established by the injection of STZ. After some weeks erection function was examined by apomorphine injection. The content of NF-κB in the erectile tissue was evaluated by immunohistochemistry staining. At the same time the activity of NF-κB was detected by electrophoretic mobility shift assay.

将成年雄性SD大鼠40只分为3组:A组为正常对照组(10只),B组为糖尿病4周组(14只),C组为糖尿病12周组(16只),采用腹腔注射STZ法制作糖尿病模型。B组大鼠于4周后,A组、C组大鼠于12周后通过注射阿朴吗啡后评价勃起功能,并取阴茎海绵体组织免疫组化EnVision法分析NF-κB的分布与表达,同时采用电泳迁移率变动分析法进行NF-κB 活性检测。

Methods All of 40 male Sprague-Dawley rats were divided into 3 groups: control group (group A, n=10), diabetic group for 4 weeks (group B, n=14), and diabetic group for 12 weeks (group C, n=16). The diabetes model was established by the injection of STZ. After some weeks erection function was examined by apomorphine injection. The content of NF-κB in the erectile tissue was evaluated by immunohistochemistry staining. At the same time the activity of NE-κB was detected by electrophoretic mobility shift assay.

将成年雄性SD大鼠40只分为3组:A组为正常对照组(10只),B组为糖尿病4周组(14只),C组为糖尿病12周组(16只),采用腹腔注射STZ法制作糖尿病模型。B组大鼠于4周后,A组、C组大鼠于12周后通过注射阿朴吗啡后评价勃起功能,并取阴茎海绵体组织免疫组化EnVision法分析NF-κB的分布与表达,同时采用电泳迁移率变动分析法进行NF-κB活性检测。

Accompanied with the long course of diabetes, the chanciness of macroangiopathy was increasing.type 2 diabetes mellitus, high blood pressure, macroangiopathy

2型糖尿病合并高血压患者大血管病变与糖尿病病程有关,糖尿病病程越长则发生大血管病变的危险性增加。

should take seriously in diabetic education diabetic sufficient precaution protects manage education, enhance a patient to be opposite the protective consciousness of sufficient ministry, the educational guidance strength of knowledge of appropriate to choice, dress footgear in increasing pair of diabetics to nurse in sufficient ministry, in order to decrease diabetic sufficient happening.

在糖尿病教育中要重视糖尿病足的预防护理教育,增强患者对足部的保护意识,加大对糖尿病患者在足部护理中对选择、穿着合适鞋袜知识的教育指导力度,以减少糖尿病足的发生。

There were no significant difference between diabetics in hospital and diabetics who had participated diabetes education in gender,age,marital status,occupation, education level and the form of medical expenses.It is suggested that the two groups come from the same patients. 2.According to the result of content validity and retest reliability,questionnaire of compliance has a good validity and reliability.According to the result of consistence test,collection validity,discrimination validity and construct validity,SF-36 has a good validity and reliability.3.We used self paired comparison to analyze the data of the treatment compliance from the patients who had participated diabetes education and the patients in hospital who hadn\'t participated diabetic education.The results suggest that the treatment compliance of patients is improved as the number of times that these patients participated diabetes education was increased.The treatment compliance of the patients in hospital is improved just in a short-term period,who hadn\'t participated diabetes education.

研究结果1、住院糖尿病患者与参加健康教育的糖尿病患者在性别、年龄、婚姻、职业、文化程度、医疗用度承担形式上均无统计学差异,说明两组人群来自同一整体。2、根据内容效度和重测信度的结果证实允从性问卷具有良好的信度和效度;根据内部一致性检验、集合效度、区分效度和结构效度的结果证实SF-36量表具有良好的信度和效度。3、对参与健康教育的糖尿病患者进行的允从性跟踪调查结果进行自身配对前后比较,并与未参加健康教育的住院糖尿病患者的允从性得分进行比较,发现糖尿病患者治疗允从性随着参加健康教育次数的增多而进步;未参加教育的住院患者治疗允从性在进院和刚出院的短期内有一定进步,但随后逐渐下降至进院前水平。

RESULTS The blood glucose level in treatment group was decreased, and there were significantly difference compared with control group; the extract of Amomum Xanthoides had protective effects on β-cells in pancreatic islets and improved morphology of β-cells in pancreatic islets in diabetic rats.

结果]糖尿病治疗组大鼠血糖明显降低,与糖尿病对照组比较有显著性差异;砂仁提取物对糖尿病大鼠胰岛β细胞具有明显的保护作用,并可改善胰岛β细胞超微结构变化。

Tongluofangji could improve the antioxidative ability, inhibit lipid peroxide and protect the aorta thoracica endothelia in diabetic rats,and further proved diabetic angiopathy belongs to Luobing.Tongluofangji would be a new kind of drugs for the prophylaxis and treatment of the diabetic chronic complication.

通络方剂能提高糖尿病大鼠机体抗氧化能力,抑制脂质过氧化,对糖尿病所致的大鼠血管内皮损害具有一定的保护作用,进一步证明糖尿病血管病变属于络病范畴,通络方剂有望成为糖尿病慢性并发症的防治药物。

Objective:To study the differences in the types of cerebral infarction,blood coagulation function and outcomes between the infracted patients with and without diabetes mellitus.

目的:探讨脑梗死合并2型糖尿病与单纯脑梗死之间的血脂水平、凝血功能及预后的差异。方法:将70例脑梗死合并2型糖尿病病人设为糖尿病组,62例单纯脑梗死病人设为非糖尿病组,两组均给予相同的抗凝、抗血栓、脱水、降压和改善微循环等治疗。

RESULTS: According to the documents, the stagnant blood symptoms was the important etiopathogenisis and pathogenesis of the disease, the promoting blood flow method was the important treatment According to the retrospective clinical observation, we found that the patients had stagnant blood symptoms According to picture of the tongue and pulse tracings indicated the stagnant blood symptoms which occupied 94%/76%.

结果: 通过古代和现代文献的调研,提示瘀血是糖尿病肾病的重要的病因病机,活血化瘀法是从古至今治疗糖尿病贤病必不可少的重要治法。通过对糖尿病贤病的回顾性临床观察,我们发现患者不同程度瘀血的证候特点,其中具有瘀血表现的舌象和脉象比较普遍,分别占94%和76%,中医诊断的重要手段,从糖尿病贤病患者、舌、脉表现,提示了瘀血是糖尿病贤病的重要临床徵象。

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