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Methods RDW values of 45 hepatic anemia,45 renal anemia and 55 diabetic anemia patients were measured by Sysmex SF3000 hemocyte analyzer and were compared with each other.45 healthy examiners were used as normal controls.

用Sysmex SF-3000全自动血细胞分析仪测定45例肝性贫血、45例肾性贫血和55例糖尿病性贫血患者的RDW值,比较三者RDW值的差异。

Along with the development of the economy and the change of people's life style, the diabetes has a morbidity rate to hoick, the outbreak rate of the diabetic foot is also increased gradually,became the main reason of amputation without trauma,and brought heavy burden for sufferer and society.

随着经济的发展和人们生活方式的改变,糖尿病患病率急剧上升,糖尿病足的发病率也逐渐增高,成为非创伤性截肢的主要原因,而且给患者和社会带来了沉重的负担。

In the experiment, an approach was made to the cause of DRP and the mechanism of it's prevention and treatmend by acupuncture. The experimental results indicated that in rat with diabetes,(1) plasma TXB2 and the ratio of TXB2 to 6-keto-PGF1α increased obviously, suggesting hyperfunction of platelet and injury to endothelial function, which tend to result in thrombosis;(2) erythrocytic filtration index increased remarkably, suggesting erythrocytic transforming and oxygen carring hypofunction, which is one of the factors leading to retinal anoxia;(3) hyperglycemia persisted, which is related to the thickening of basilar membrane of and the decrease of mural cell of retinal blood vessels;(4) serum growth hormone rose notably, which is not only one of the important factors causing basilar membrane thickening but also promotes the synthesis or Von Willebrand Factor that participates in a tendency to thrombosis.

本实验对糖尿病性视网膜病变(Diabetic Retinopathy,DRP)的成因以及针刺防治DRP的作用机理进行了探讨,实验结果表明:糖尿病大鼠(1)血浆TXB2及TXB2/6-ket0-PGF1α比值均显著升高,提示其血小板机能亢进,内皮细胞功能损伤,具有血栓形成倾向;(2)红细胞滤过指数(Filtration Index,IF)显著增高,提示其红细胞变形能力低下,携氧运行功能降低,是造成视网膜缺氧状态的因素之一;(3)呈持续高血糖状态,与视网膜血管基底膜增厚及管壁细胞减少有关;(4)血清生长激素(Growth Hormone,GH)水平明显升高,既是导致基底膜增厚的重要因素之一,又促进VWF合成,参与血栓形成倾向。

Background: Diabetic scleredema is a nonpitting, woody, peau d'orange quality of skin characters.

摘要 背景:糖尿病性硬肿症是一种无痛性、慢性、对称性皮肤会变硬变厚的病变。

Diabetic retinopathy is one of the most serious microvessel complications of diabetes,it is a main cosmopolitan blindness disease. In recent years, with the molecular biology development, the recognition of the mechanism of DR is more profound and consummate. Most researchers consider that hyperglycaemia, polyalcohol inositol metabolism abnormality, changes of hemorrheology, oxidative stress, inflammation/immune system activation, cytokines/growth factors expression or activity change and so on result in DRs onest and development.

糖尿病性视网膜病变(diabetic retinopathy, DR)是糖尿病最严重的微血管并发症之一,也是一种世界性的主要致盲眼病,近年来随着分子生物学方面的研究进展,对DR发病机制的认识进一步深入和完善,认为高血糖、多元醇肌醇代谢异常、血液流变学改变、氧化应激、炎症/免疫系统活化、细胞因子/生长因子表达或活性改变等导致DR的发生发展。

The present invention is directed to substituted propylamine derivatives of formula I or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

本发明涉及式I的取代丙胺衍生物或其医药学上可接受的盐、含有这些衍生物的组合物、和其用于预防和治疗通过单胺再摄取改善的病状的使用方法,所述病状尤其包括血管舒缩症状、性功能障碍、胃肠道和泌尿生殖道病症、慢性疲劳综合症、纤维肌痛综合症、神经系统病症和其组合,特别是那些选自由严重抑郁症、血管舒缩症状、压力性和急迫性尿失禁、纤维肌痛、疼痛、糖尿病性神经病变和其组合组成的群组的病状。

To study expression of uncoupling proteins homologues in retina of rats. To observe changes of mRNA expression of UCPs and MnSOD in different courses of diabetes.

检测正常大鼠视网膜中UCPs的表达类型,以及UCPs、MnSOD mRNA表达随糖尿病病程的变化,探讨糖尿病性视网膜病变发病的分子机制。

The motor and sensory nerve conduction velocity of the left peronaeus communis nerve was observed before and after the treatment.

对糖尿病性周围神经病变的治疗,将是改善糖尿病患者生活质量的重要环节。

Methods The extracranial carotid arteries and proper palmar digital arteries of 80 patients with type 2 diabetic combine cerebral infarction, 30 patients with type 2 diabetic and 41 healthy collators were detected by colour-Doppler ultrasound ,the relationships between carotid IMT and risk factors of cerebrovascular disease were evaluated .

利用彩色多普勒超声对 80 例 2 型糖尿病性脑梗死患者、30 例单纯糖尿病患者及 41 例性别、年龄匹配的健康对照人群的颈动脉和指动脉进行检测,并分析颈动脉内中膜厚度与脑血管病危险因素间的关系。

Objective To investigate the lipoprotein concentration and apolipoprotein 〔apo〕 polymorphism in type 2 diabetic patients and its relationship to complications.

目的 研究2型糖尿病患者的脂蛋白〔Lp〕浓度和载脂蛋白〔apo〕的多态性以及与糖尿病慢性并发症的关系。

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