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Objective: 1 To study the relationship of type 2 diabetes mellitus and osteoporosis.

目的: 一、探讨2型糖尿病患者骨密度的变化;二、探讨雌激素受体基因多态性与2型糖尿病患者BMD的关系。

Methods: First, the ulcerative surface of diabetic foot was evaluated. Then, different neotype dressings were chosen according to different conditions. By using "moist healing" theory, 48 patients with diabetic foot ulcer were studie; while another 48 patients with diabetic foot ulcer, treated with traditional therapy, were selected as controls.

首先评估糖尿病足溃疡创面,然后根据不同情况采用不同新型敷料,应用湿性伤口愈合理论对48例糖尿病足溃疡的患者进行临床研究,选取48例传统方法处理的同类患者作为对照。

Methods 68 cases of hepatogenous diabetes were examined of history tests for clinical feature and method of treatment.

对肝源性糖尿病68例患者临床表现特点、糖尿病病情与肝功能分级的关系、胰岛素抵抗与肝功能分级的关系、治疗方法进行回顾性分析。

BACKGROUND To discuss the effects of nutrition guidance for control of gestational diabetes mellitus and incidence of macrosomia.

妊娠性糖尿病(gestational diabetes mellitus,GDM)是指在妊娠后才发生或首次发现的糖尿病,世界各国报道GDM发生率为1%~14%[1]。

In 1980s, molecula biology technology had been applied to familial diabetic genetics, a suit of single genes about diabetes was found: insulin gene, insulin receptor gene and so on.

自上个世纪80年代以来,应用分子生物学技术进行家族性糖尿病遗传学研究发现了一系列与糖尿病相关联的单基因,即胰岛素基因和胰岛素受体基因等。

Furthermore, the significant risks of low birth weight among all newborns are female sex , maternal age, preterm, maternal pneumonopathy, amniotic fluid anomaly, thalassemia, interogestate smoking, interogestate drink, interogestate drug addiction, had preterm or birth weight, pre-eclampsia, nephritic disease, chronic hypertension, gestation hypertension and cervical incompetence.

其次发现不论在全体、单胞胎及双胞胎上,在早产方面,新生儿性别为男性、产妇身分为本国、产妇年龄、低出生体重、产妇心脏疾病、产妇肺病、产妇羊水异常、产妇海洋性贫血、产妇孕期抽烟、产妇孕期酗酒、产妇药瘾、产妇曾生早产或低出生体重儿、产妇糖尿病、产妇妊娠糖尿病、产妇梅毒、产妇妊娠毒血症、产妇肾脏病、产妇怀孕高血压、产妇子宫颈闭锁不全皆会增加早产的风险。

The autoimmune thyroid disease mainly involve Graves disease 、 chronic lymphocytic thyroiditis 、 atrophic thyroiditis and opthalmopathy of Graves disease . LADA combined with Graves disease can include in a type of autoimmune polyglandular syndrome type II .

成人隐匿性自身免疫性糖尿病是T1DM的一个亚型,AITD主要包括Graves病、慢性淋巴细胞性甲状腺炎、萎缩性甲状腺炎和Graves眼病。

NOD/SCID (non-obese diabetic/severe combined immunodeficient) mice are immunodeficient mice which are generated by backcrossing severe combined immunodeficient mice with non-obese diabetic mice strains.

NOD/SCID(非肥胖糖尿病/重症联合免疫缺陷)小鼠是在SCID小鼠的基础上与非肥胖性糖尿病小鼠品系回交的免疫缺陷鼠。

D. N big mouse model was successfully made by adopting single side kidney cutting with induction, then by 24 week continuos observation on the change of various values of kidney and function, through testing of immunity florescence, electro-scope and optical scope, what we can see from model group is that typical kidney small cell got hardened by knot, and discarded, and dead, also small tube withered, small cell of on base film got thick, cell capsule wall was fibred, and base film got double layered.

实验研究采用单侧肾切除加以链脲佐菌素诱导,成功地复制出糖尿病肾病大鼠模型,对其肾脏结构和功能的改变各项指标,连续进行24周动态观察,并进行免疫荧光、电镜、光镜检测,结果表明:糖尿病肾病模型组可见典型的肾小球节段硬化、废弃、坏死,有大量蛋白管型,肾小球管糖元空泡沉积及脂肪滴,肾小管萎缩,肾小球基底膜明显增厚,球囊壁纤维化,基底膜双层化,有一例结核性肉芽组织及钙化等病理变化。

Methods: A total of 56 pedigreed members were collected. 62 patients with type 2 diabetes mellitus and 82 healthy were collected as controls. HNF-1β gene exon2 from all subjects were examined by polymerase chain reaction-single strand conformation polymorphism.

运用聚合酶链反应-单链构象多态性技术检测2型糖尿病患者62例,健康献血者82例,11个糖尿病家系中56例糖尿病肾病患者的HNF-1β基因exon2片段。

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