糖尿病

The patients with type 2 DM have disproportionally increased PI/IRI.IRI may overestimate insulin levels in individuals with obesity,type 2 DM and IGT.

肥胖者、肥胖的IGT患者和肥胖的新诊断的2型糖尿病患者具有高胰岛素血症。2型糖尿病患者具有不成比例的前胰岛素的增高，免疫活性胰岛素常常过高估计肥胖者、2型糖尿病和IGT患者的胰岛素水平。

To make full use of our drug and bring evangel to the diabetes, we plan to search new pharmacodynamicseffect of Jin Tang Ning Capsule in symptoms like Diabetes Chronic Complications, abnormal glucose tolerance, insulin resistance. It will supply more convenience and support to the therapy of diabetes in the field of Chinese traditional medicine.

为更好的发扬我们的产品优势，为更多的糖尿病患者带来福音，我们拟从改善糖尿病慢性并发症、糖耐量异常、胰岛素抵抗等对金糖宁做进一步的药效药理和临床研究，寻找新适应症，为中药在治疗糖尿病的发展提供更多的服务与支持。

To make full use of our drug and bring evangel to the diabetes, we plan to search new pharmacodynamics effect of Jin Tang Ning Capsule in symptoms like Diabetes Chronic Complications, abnormal glucose tolerance, insulin resistance. It will supply more convenience and support to the therapy of diabetes in the field of Chinese traditional medicine.

为更好的发扬我们的产品优势，为更多的糖尿病患者带来福音，我们拟从改善糖尿病慢性并发症、糖耐量异常、胰岛素抵抗等对金糖宁做进一步的药效药理和临床研究，寻找新适应症，为中药在治疗糖尿病的发展提供更多的服务与支持。

Result: Among 40 cases of hyperpiesia, there are 32 cases with arteria carotis atherogenesis in different extent, and its incidence is 80%; Among 32 cases of cerebral vessels diseases: Twenty-one cases had arteria carotis atherogenesis, and its incidencewas 66%. Among 18 cases of diabetes complicated with hyperpiesia, 13 cases had arteria carotis atherogenesis, and its incidence was 72%; Among 6 cases of diabetes, 2 cases had arteria carotis atherogenesis, and its incidence was 33%.

结果 40例高血压患者中，32例颈动脉有不同程度的粥样斑块形成，发病率80％；32例脑血管病变患者，21例颈动脉有不同程度的粥样斑块形成，发病率66％；糖尿病合并高血压18例糖尿病患者中，13例颈动脉有不同程度的粥样斑块形成，发病率72％；6例糖尿病患者中，2例颈动脉有不同程度的粥样斑块形成，发病率33％。

Result: Among 40 cases of hyperpiesia, there are 32 cases with arteria carotis atherogenesis in different extent, and its incidence is 80%; Among 32 cases of cerebral vessels diseases: Twenty-one cases had arteria carotis atherogenesis, and its incidencewas 66%.

结果 40例高血压患者中，32例颈动脉有不同程度的粥样斑块形成，发病率80％；32例脑血管病变患者，21例颈动脉有不同程度的粥样斑块形成，发病率66％；糖尿病合并高血压18例糖尿病患者中，13例颈动脉有不同程度的粥样斑块形成，发病率72％；6例糖尿病患者中，2例颈动脉有不同程度的粥样斑块形成，发病率33％。

Most people with type 2 diabetes manage their diabetes by carefully controlling their diet, but there are some people with type 2 diabetes who also take insulin and are at risk of becoming hypo.

大多数人与2型糖尿病糖尿病管理小心控制饮食，但也有一些人与2型糖尿病的谁也采取胰岛素和有可能成为吸毒者 hypo 。

Serum levels of TIMP-1 were gradually increasing with the progression of diabetic nephropathy,The results strongly suggested that TIMP-1 may contribute to vascular remodeling during the development and progression of high blood pressure and atherosclerosis. Meanwhile, TIMP-1 may mediate remodeling of glomerular basemment membrane and glomerulos-clerosi and plays an important role in the development and progression of diabetic nephropathy.

随着糖尿病肾病的病情进展，血清中TIMP-1水平逐渐增高，提示TIMP-1可能参与了糖尿病患者动脉硬化、动脉粥样斑块的形成及高血压的血管重塑过程；TIMP-1可能介导了肾小球ECM积聚，肾小球基底膜重塑、肾小球硬化，在糖尿病肾病发生、发展过程中起着重要作用。

Results: Expression of PAI1,TIMP1 and FN in kidney of diabetic rats began to increase in the second week of diabetes; PAI1 and TIMP1mainly expressed in intracytoplasm of renal tubular epithelial cells, while FN mainly expressed in renal tubule matrix and glomerului; Their expression showed a tendency of increasing along with the progression of diabetes.

本实验以糖尿病大鼠为动物模型，动态观察糖尿病2周、4周、8周、16周大鼠肾脏PAI1、TIMP1及FN表达的变化，从ECM代谢的角度探讨PAI1和TIMP1在糖尿病肾病肾纤维化发病机制中的作用。

Ketosis and diabetic ketoacidosis was the acute complication of diabetes, but after active treatment, the nice curative effect can be acquired.

糖尿病酮症及糖尿病酮症酸中毒是糖尿病的急性并发症，但经过积极治疗能取得很好的疗效。

Our study demonstrated that decrease of lipogenesis along with increase of fatty acids oxidation of adipose tissue could be a common cause of insulin resistance in obesity and type 2 diabetes, while functional changes of other genes, such as immune regulation genes, might also be involved in the pathogenesis of obesity and type 2 diabetes.

脂肪组织中脂肪生成下降、脂肪酸氧化增加可能是肥胖及2型糖尿病中胰岛素抵抗发生的共同原因，其它基因功能的改变也可能参与了肥胖及2型糖尿病的发生，而胰岛素信号转导受阻可能是肥胖向糖尿病转化的促进因素。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。