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糖尿病

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Michiel L. Bots of University Medical Center Utrecht and colleagues note in the journal Diabetes Care.

波茨博士在新一期《糖尿病护理》杂志中指出,尽管此前的研究已经发现,饮酒和降低人们患糖尿病的危险,这两者间具有联系;但人们对这一主题的深入探索大多都集中在男性身上,很少有研究涉及到上了年纪的女性。

Meanwhile, we have found that some strains of Lactobacillus were related to the onset and development of diabetes when we studied the relationships between gut microbiota and STZ induced diabetes model through molecular ecological methods.

此外,我们实验室在采用分子生态学的方法来研究肠道菌群与STZ诱导的ICR小鼠糖尿病之间的关系时,发现一些乳杆菌与糖尿病的发生发展存在一定的关系。

In 1980s, molecula biology technology had been applied to familial diabetic genetics, a suit of single genes about diabetes was found: insulin gene, insulin receptor gene and so on.

自上个世纪80年代以来,应用分子生物学技术进行家族性糖尿病遗传学研究发现了一系列与糖尿病相关联的单基因,即胰岛素基因和胰岛素受体基因等。

2Myocardial ultrastructure was normal in the control group,myoneme arranged disordered,the structure of typical sarcomere disappeared, mitochondrium intumesced,interstitial substance fiber hyperplasy,capillary vessel endothelial cell swelled in DG group.Myocardial ultrastructure improved slightly in rats of SM and LM groups. 3NF-κB p65 and COX-2 had a small quantity to present in the myocardium tissue of control group,while the quantity increased obviously in the diabetic group.The level of it in the group of treatment was significant lower than that in the diabetic group.There was significant difference between the two groups. Conclusion Metformin can protect against the heart injury in diabetic.

结果 1与对照组比较,DG组体重明显减轻,血糖、心脏质量指数、INS、TG、T-CH及FFA明显升高(P<0.01);应用 MT治疗后体重无明显增加,INS有所下降,心脏质量指数、血糖、TG及FFA明显降低(P<0.01);DG组心肌组织MDA明显升高,SOD明显降低(P<0.01),MT治疗后上述指标明显改善;2超微结构观察单纯糖尿病组肌丝结构明显紊乱,典型肌小节结构消失,线粒体肿胀、间质纤维增生,微血管内皮细胞肿胀等表现,而SM及LM组可见组织结构有所改善;3对照组心肌NF-κB p65及COX-2只有少量表达,单纯糖尿病组表达量明显增多(P<0.01),MT治疗后表达量明显减少(P<0.01)。

In the patients with nephric insufficiency due to clinical type-II-diabetic nephropathy, urine protein level and urine protein reduction exert influence on nephric function, unrelated with LPD.

临床期2型糖尿病肾病肾功能不全患者,与饮食中低蛋白水平无关,尿蛋白水平和尿蛋白减少对肾功能的进展有影响;在评价低蛋白饮食对糖尿病肾病肾功能的影响时,要考察到尿蛋白在其中的作用。

This paper reviewed the effect of some major neurotrophic factors on diabetic neuropathy and their application in clinical treatment.

本文对一些主要的神经营养因子对糖尿病性神经病理变性及再生作用,以及神经营养因子在临床糖尿病性神经变性的应用研究作-综述。

Compared with nondiabetic patients, diabetic patients had higher rates of infectious and noninfectious complications, as well as higher lengths of stay overall and in the intensive care unit.

相比于非糖尿病患者,糖尿病患者有较高的感染和非感染的并发症,且总体住院时间增加。

Type 2 diabetic patients show lower transcription of adiponectin mRNA in omental adipose tissue than that of non-diabetic control.

2 型糖尿病患者大网膜脂肪组织脂联素 mRNA 达显著降低,其表达水平可以作为胰岛素抵抗的重要参数;WC、TG、FBG、WHR、病程等临床指标,可间接反应 IR 的程度,而且以 WC 的参考意义最大;糖尿病的病程尤其是 5 年以上的病程也可以作为 IR 的一个重要参考指标。

Methods Diabetic rat models were prepared by giving alloxan. After administration of sodium orthovanadate for seven days, the blood glucose levels of rats were determined. The glucose tolerances of diabetic rats were evaluated by the oxidation-enzyme method, and the insulin levels were determined by radioimmunoassay.

建立四氧嘧啶诱导的糖尿病大鼠模型,对正常大鼠及糖尿病大鼠给予原钒酸钠治疗7天后,采用葡萄糖氧化酶法测定大鼠的血糖值、糖耐量,并以放射免疫法测定血清胰岛素值。

To furtherexplore the relationship beween bone mineral density and level of sex hormone in elderlymen with diabetes mellitus and the influence of diabetes mellitus on osteal metabolism.

黄萍目的:为探讨老年男性糖尿病患者的骨密度的改变以及与性激素水平的关系,更深入了解糖尿病对骨代谢的影响。

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