糖尿病

Methods All of 40 male Sprague-Dawley rats were divided into 3 groups: control group (group A, n=10), diabetic group for 4 weeks (group B, n=14), and diabetic group for 12 weeks (group C, n=16). The diabetes model was established by the injection of STZ. After some weeks erection function was examined by apomorphine injection. The content of NF-κB in the erectile tissue was evaluated by immunohistochemistry staining. At the same time the activity of NE-κB was detected by electrophoretic mobility shift assay.

将成年雄性SD大鼠40只分为3组：A组为正常对照组（10只），B组为糖尿病4周组（14只），C组为糖尿病12周组（16只），采用腹腔注射STZ法制作糖尿病模型。B组大鼠于4周后，A组、C组大鼠于12周后通过注射阿朴吗啡后评价勃起功能，并取阴茎海绵体组织免疫组化EnVision法分析NF-κB的分布与表达，同时采用电泳迁移率变动分析法进行NF-κB活性检测。

Poorly controlled gestational diabetes is associated with an increase in the incidence of preeclampsia,polyhydramnios,fetal macrosomia,birth trauma,operative delivery,and neonatal hypoglycemia.

控制不好的糖尿病期糖尿病与先兆子痫，羊水过多，巨大儿，产伤，手术分娩，和干细胞糖尿病足低糖血症的发生率升高有关。

More than 6 million people worldwide have taken Avandia since it came on the market in 1999 to treat Type 2, the most common form of diabetes and the one linked with obesity.

型糖尿病是最常见的一种糖尿病，与肥胖相关，自从文迪雅1999年上市治疗Ⅱ型糖尿病，已经有600百万以上的患者服用。

More than 6 million people worldwide hae taken Aandia since it came on the market in 1999 to treat Type 2, the most common form of diabetes and the one linked with obesity.

型糖尿病是最常见的一种糖尿病，与肥胖相关，自从文迪雅1999年上市治疗Ⅱ型糖尿病，已经有600百万以上的患者服用。

Accompanied with the long course of diabetes, the chanciness of macroangiopathy was increasing.type 2 diabetes mellitus, high blood pressure, macroangiopathy

2型糖尿病合并高血压患者大血管病变与糖尿病病程有关，糖尿病病程越长则发生大血管病变的危险性增加。

"Our goal now is to identify a marker in the blood that will enable us to distinguish diabetes associated with pancreatic cancer from the far more common type 2 diabetes, so we are able to screen patients with new-onset diabetes to detect pancreatic cancer before it spreads," said lead investigator Dr. Suresh Chari, M.D., a gastroenterologist at the Mayo Clinic.

美国Mayo诊所的消化科专家、首席研究员Suresh Chari博士指出："我们现在的目标是鉴别一种血液中的指标，这种指标能够帮助我们区别与胰腺癌相关的糖尿病以及常见的普通2型糖尿病，这样我们就能够对新发糖尿病患者，在扩散之前就进行筛查胰腺癌。"

University of Central Florida biomedical scientists led by Professor Henry Daniell found insulin might someday be grown in genetically modified plants and then be used to prevent diabetes before symptoms appear or to treat the disease in its later stagesDaniell's research team genetically engineered tobacco plants with the insulin gene and then administered freeze-dried plant cells to five-week-old diabetic mice as a powder for eight weeks.

在弗罗里达中央大学，由Henry Daniell教授带领的生物医学学家们发现胰岛素可以在转基因植物中生产，以用来在症状出现之前预防糖尿病或在疾病晚期治疗糖尿病。Daniel的研究小组将胰岛素基因通过基因工程技术重组到烟草植物之中，再将经过冷冻干燥过的植物细胞用作粉剂喂食五周大的糖尿病鼠8周。

Sixty SD rats were with rosiglitazone group, ty1e 2 diabetes mellitus (T2DM) model group, T2DM with rosiglitazone group arid T2DM will; decimeter wave group.

将60只SD大鼠随机分为4组，即正常对照组、糖尿病模型组、糖尿病罗格列酮治疗组和糖尿病分米波治疗组。

So far, It is accepted that insulin secretion function defection and insulin resistance is the feature of T2DM.

糖尿病的发病机制十分复杂，迄今为止，认为糖尿病是一个涉及多因素异质性疾病，胰岛素分泌缺陷和胰岛素抵抗在整个糖尿病的发展过程中起重要作用。

RESULTSdiabetic rats showed typical symptoms involving elevated serum glucose and weight loss (2)The rats in DM+VaD group reacted slower and made more error numbers in Y-maze than the rats in VaD group did, with a prolonged total reacting time in a whole day.(3)More neurons with serious damages, such as edema, ischemia or pyknosis could be found in DM+VaD group than in VaD group. More disarrangement of cone neurons, obvious glia proliferation, and more neuron apoptosis were found in CA area of hippocampus. CONCLUSIONS (1)2-VO in STZ-induced diabetic rats succeeded in establishing VaD animal models.(2) The cognitive dysfunction induced by VaD rats had been deteriorated by diabetes mellitus.(3)Morphology evidences proved that diabetes mellitus aggravated brain damages induced by VaD.PART II Effect of diabetes mellitus on the cholinergic nervous systemin CA1 area of hippocampus of VaDOBJECTIVE To estimate the role of cholinergic nervous system in hippocampus during the process of cognitive dysfunction aggravated by diabetes mellitus in DM+VaD group. METHODS Observe the changes of ChAT protein by immunohistochemistry stain. Chose three rats randomly from each group at each pointat two week, four week, and eight week, then sepa

经腹腔注射链脲佐菌素诱导慢性实验性糖尿病，1周后永久性结扎双侧颈总动脉(2-VO)制作VaD模型记录术后2周、4周和8周各组大鼠的体重及血糖；应用Y-迷宫检测空间定向学第二军医大学博士论文中…丈摘…要1ia；一色恤~﹁染澎糕行HE染色观察组织病理学孪叱；胶质细胞原纤维酸性蛋白protellZ，Cf冰尸标记观察星形胶质细舱的激活情况、橄声软公点娜育票票众糯黑橄居端粗默孺篇筑价井袱第二部分糖尿病对血管性痴呆大鼠海马c心区胆碱能神经系统的影响探讨海马CAI区胆碱能神经系统在糖尿病加重确D一大鼠认知障碍中所实验动物及分组同第一部分，应用免疫组织化学染色方法现察海马CAI{介狱牛第晕军l袭拔常博粗{论义

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。