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The protein encoded by this sequence was deduced to be consisted with 213 amino acids, signal peptide sequence from 1 to 17 position, and transmembrane regions from 171 to 190 position, whose grand average of hydropathicity is computed to be 0.031, secondary structure is composed by alpha helix (57.28%), extended strand (6.57%) and random coil (36.15%), subcellular localization was cytoplasmic by CELLO v.2.5. There are some function sites predicted by PROSCAN software, such as one N-glycosylation site (151-154aa), one protein kinase C phosphorylation site (193-195aa), two casein kinase II phosphorylation sites (155-158aa and 173-176aa), and one N-myristoylation site (97-102aa).

推测编码蛋白由213个氨基酸组成,信号肽序列位于1-17aa,亲水性指数为0.031,跨膜区域位于171-190aa,二级结构由-螺旋(57.28%)、延伸主链(6.57%)和无规卷曲(36.15%)组成;亚细胞定位于细胞质,含有N-糖基化位点1个(151-154aa),蛋白激酶C磷酸化位点1个(193-195aa),酪蛋白激酶Ⅱ磷酸化位点2个(155-158aa and 173-176aa),N端酰基化位点1个(97-102aa)。

Galactosyltransferase 1 is the first cloned glycosyltransferase. It had been regarded as a house-keeping gene for a long time. In our previous investigation, it was found that GaT I was an intraction protein of SGT, and EIAF, one of the Ets family members could regulat its expression.

1,4半乳糖基转移酶是一个最早克隆的糖基转移酶,长期以来被认为是一个管家基因,本实验室以前的工作表明GalT Ⅰ是SGT的一个相互作用蛋白,Ets转录因子家族的成员EIAF可调控其基因的转录。

One such base and its attached sugar radical is called a "nucleotide."

一个这样的碱基和它附着的糖基被称为-"核糖"。

It was noted that the protein bands between 23 ku and 40 ku which bound to ulex europaeus agglutinin and lens culinaris agglutinin reduced significantly until 20 weeks when the liver mass formed, but the band at 80 ku became denser week after week during the course of rat hepatocarcinogenesis induced by N nitrosodiethylamine.

在化学诱发的大鼠肝癌过程中,分子质量在 2 3ku到 4 0ku范围内与荆豆凝集素及扁豆凝集素结合的岩藻糖糖基化蛋白显著减少,诱癌至 17~ 2 0周这些条带重新恢复,而分子质量为 80ku的条带却在诱癌过程中逐周增加。

Recent progress in regioselective synthesis of oligosaccharides with lightly protected glucosamine and galactose as acceptors was also outlined.

本文同时简述了用少保护的半乳糖和氨基葡萄糖为糖基受体合成寡糖的进展。

Abundant in hydrolyzed extensin, glycosyl trehalose and tocopheryl acetate, it gives the skin more nutrition and care and helps reduce traces of time, making the skin bright, delicate and tighter.

丰富水解伸展蛋白、糖基海藻糖和生育酚乙酸酯,给肌肤更多滋润呵护,帮助减少岁月痕迹,令肌肤明亮、细腻更紧致。

Mucins are heavily O-glycosylated glycoproteins found in mucous secretions and as transmembrane glycoproteins of the cell surface with the glycan exposed to the external environment .

黏蛋白是细胞表面的或分泌的、具有高度O-糖基化修饰的糖蛋白。

It′s death rate locates the top among gynecological malignant tumors.Mucins is a family of high-glycosylated and high-molecular weight glycoprotein,which is distributed on the surface of body epithelial cells.In cancer cells,the expression of mucins is obviously high and their structures and functions are changed.Mucins are directly implicated in the infiltration and metastasis of ovarian tumors.

黏蛋白是一类高度糖基化、相对分子质量高的糖蛋白,分布于人上皮细胞表面,在卵巢上皮性肿瘤中表达水平明显上调,出现异常表达,其结构和功能发生改变,直接参与了肿瘤的浸润和转移,因而与卵巢肿瘤的发生、发展及预后相关。

The increasing singlets of protons from acetyl group of product were treated as a reporter of the reaction progress. The reaction yields are calculated by the HR/MAS NMR.

利用四个羟基未保护的Nα-Fmoc氨基酸和七种全乙酰化糖为原料,合成了28个糖基化Nα-Fmoc氨基酸,均用高分辨魔角核磁共振技术定量。

Von willebrand factor is one glycosylated protein synthesized by blood vessel endothelial cell.Thrombomodulin is one glucoprotein which exists in blood vessel endothelial cell surface.Both of their levels are increased obviously when endotheliocyte is damaged,so they could be considered as the molecular markers reflecting endothelial injury.

血管性假血友病因子是血管内皮细胞合成的一种糖基化蛋白,血栓调节蛋白是位于血管内皮细胞表面的糖蛋白,内皮细胞损伤时,二者水平均显著升高,因此它们作为反映内皮损伤的分子标记物。

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